3JXT
Crystal structure of the third PDZ domain of SAP-102 in complex with a fluorogenic peptide-based ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Disks large homolog 3 | polymer | 104 | 11145.4 | 2 | UniProt (Q62936) Pfam (PF00595) | Rattus norvegicus (rat) | Synapse-associated protein 102, SAP102, PSD-95/SAP90-related protein 1 |
| 2 | C, D (C, D) | Voltage-dependent calcium channel gamma-2 subunit | polymer | 7 | 873.0 | 2 | UniProt (O88602) | Neuronal voltage-gated calcium channel gamma-2 subunit, Stargazin | |
| 3 | E (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 4 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 340 | Chemie (HOH) |
Sequence modifications
A, B: 393 - 493 (UniProt: Q62936)
C, D: 101 - 106 (UniProt: O88602)
| PDB | External Database | Details |
|---|---|---|
| Ser 390 | - | expression tag |
| Gly 391 | - | expression tag |
| Ser 392 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ace 100 | - | insertion |
| 4db 101 | Arg 318 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 24036.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 59.0 | |
| All* | Total formula weight | 24095.7 |
