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3JXT

Crystal structure of the third PDZ domain of SAP-102 in complex with a fluorogenic peptide-based ligand

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Disks large homolog 3polymer10411145.42UniProt (Q62936)
Pfam (PF00595)
Rattus norvegicus (rat)Synapse-associated protein 102, SAP102, PSD-95/SAP90-related protein 1
2C, D
(C, D)
Voltage-dependent calcium channel gamma-2 subunitpolymer7873.02UniProt (O88602)Neuronal voltage-gated calcium channel gamma-2 subunit, Stargazin
3E
(A)
ACETATE IONnon-polymer59.01Chemie (ACT)
4F, G, H, I
(A, B, C, D)
waterwater18.0340Chemie (HOH)
Sequence modifications
A, B: 393 - 493 (UniProt: Q62936)
PDBExternal DatabaseDetails
Ser 390-expression tag
Gly 391-expression tag
Ser 392-expression tag
C, D: 101 - 106 (UniProt: O88602)
PDBExternal DatabaseDetails
Ace 100-insertion
4db 101Arg 318engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight24036.7
Non-Polymers*Number of molecules1
Total formula weight59.0
All*Total formula weight24095.7
*Water molecules are not included.

239149

PDB entries from 2025-07-23

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