2RIW
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![BU of 2riw by Molmil](/molmil-images/mine/2riw) | The Reactive loop cleaved human Thyroxine Binding Globulin complexed with thyroxine | Descriptor: | 3,5,3',5'-TETRAIODO-L-THYRONINE, Thyroxine-binding globulin | Authors: | Zhou, A, Wei, Z, Stanley, P.L.D, Read, R.J, Stein, P.E, Carrell, R.W. | Deposit date: | 2007-10-12 | Release date: | 2008-10-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins J.Biol.Chem., 286, 2011
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2V95
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![BU of 2v95 by Molmil](/molmil-images/mine/2v95) | Structure of Corticosteroid-Binding Globulin in complex with Cortisol | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN | Authors: | Klieber, M.A, Muller, Y.A. | Deposit date: | 2007-08-21 | Release date: | 2007-09-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Corticosteroid-Binding Globulin: Structural Basis for Steroid Transport and Proteinase-Triggered Release J.Biol.Chem., 282, 2007
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5NCW
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![BU of 5ncw by Molmil](/molmil-images/mine/5ncw) | Structure of the trypsin induced serpin-type proteinase inhibitor, miropin (V367K/K368A mutant). | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ... | Authors: | Goulas, T, Ksiazek, M, Garcia-Ferrer, I, Mizgalska, D, Potempa, J, Gomis-Ruth, X. | Deposit date: | 2017-03-06 | Release date: | 2017-05-24 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A structure-derived snap-trap mechanism of a multispecific serpin from the dysbiotic human oral microbiome. J. Biol. Chem., 292, 2017
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2VH4
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![BU of 2vh4 by Molmil](/molmil-images/mine/2vh4) | Structure of a loop C-sheet serpin polymer | Descriptor: | TENGPIN | Authors: | Zhang, Q, Law, R.H.P, Bottomley, S.P, Whisstock, J.C, Buckle, A.M. | Deposit date: | 2007-11-19 | Release date: | 2008-01-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | A Structural Basis for Loop C-Sheet Polymerization in Serpins. J.Mol.Biol., 376, 2008
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5M3X
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![BU of 5m3x by Molmil](/molmil-images/mine/5m3x) | |
2VDX
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![BU of 2vdx by Molmil](/molmil-images/mine/2vdx) | |
5OM6
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![BU of 5om6 by Molmil](/molmil-images/mine/5om6) | |
2VDY
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![BU of 2vdy by Molmil](/molmil-images/mine/2vdy) | Crystal structure of the reactive loop cleaved Corticosteroid Binding Globulin complexed with Cortisol | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN | Authors: | Zhou, A, Wei, Z, Read, R.J. | Deposit date: | 2007-10-13 | Release date: | 2008-05-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The S-to-R Transition of Corticosteroid-Binding Globulin and the Mechanism of Hormone Release. J.Mol.Biol., 380, 2008
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5NBU
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![BU of 5nbu by Molmil](/molmil-images/mine/5nbu) | |
5OM8
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![BU of 5om8 by Molmil](/molmil-images/mine/5om8) | |
5OM5
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![BU of 5om5 by Molmil](/molmil-images/mine/5om5) | |
5OM2
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![BU of 5om2 by Molmil](/molmil-images/mine/5om2) | Crystal structure of Alpha1-antichymotrypsin variant DBS-I1: a drug-binding serpin for doxycycline | Descriptor: | (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin | Authors: | Schmidt, K, Muller, Y.A. | Deposit date: | 2017-07-28 | Release date: | 2018-05-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5NCS
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![BU of 5ncs by Molmil](/molmil-images/mine/5ncs) | Structure of the native serpin-type proteinase inhibitor, miropin. | Descriptor: | Serpin | Authors: | Goulas, T, Ksiazek, M, Garcia-Ferrer, I, Mizgalska, D, Potempa, J, Gomis-Ruth, X. | Deposit date: | 2017-03-06 | Release date: | 2017-05-24 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A structure-derived snap-trap mechanism of a multispecific serpin from the dysbiotic human oral microbiome. J. Biol. Chem., 292, 2017
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2QUG
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![BU of 2qug by Molmil](/molmil-images/mine/2qug) | Crystal structure of alpha-1-antitrypsin, crystal form A | Descriptor: | Alpha-1-antitrypsin | Authors: | Hansen, G, Morton, C.J, Pearce, M.C, Feil, S.C, Adams, J.J, Parker, M.W, Bottomley, S.P. | Deposit date: | 2007-08-05 | Release date: | 2008-08-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Preventing serpin aggregation: The molecular mechanism of citrate action upon antitrypsin unfolding. Protein Sci., 17, 2008
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5OM3
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![BU of 5om3 by Molmil](/molmil-images/mine/5om3) | Crystal structure of Alpha1-antichymotrypsin variant DBS-I5: a MMP14-cleavable drug-binding serpin for doxycycline | Descriptor: | (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, Alpha-1-antichymotrypsin, DI(HYDROXYETHYL)ETHER | Authors: | Schmidt, K, Muller, Y.A. | Deposit date: | 2017-07-28 | Release date: | 2018-05-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5OM7
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![BU of 5om7 by Molmil](/molmil-images/mine/5om7) | |
2WY1
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![BU of 2wy1 by Molmil](/molmil-images/mine/2wy1) | |
2WXW
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![BU of 2wxw by Molmil](/molmil-images/mine/2wxw) | |
2WXX
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![BU of 2wxx by Molmil](/molmil-images/mine/2wxx) | |
2WY0
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![BU of 2wy0 by Molmil](/molmil-images/mine/2wy0) | Crystal structure of mouse angiotensinogen in the oxidised form with space group P6122 | Descriptor: | 1,2-ETHANEDIOL, ANGIOTENSINOGEN, SODIUM ION | Authors: | Zhou, A, Wei, Z, Carrell, R.W, Read, R.J. | Deposit date: | 2009-11-11 | Release date: | 2010-10-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | A Redox Switch in Angiotensinogen Modulates Angiotensin Release. Nature, 468, 2010
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2WXZ
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![BU of 2wxz by Molmil](/molmil-images/mine/2wxz) | |
1BY7
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![BU of 1by7 by Molmil](/molmil-images/mine/1by7) | |
1BR8
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![BU of 1br8 by Molmil](/molmil-images/mine/1br8) | IMPLICATIONS FOR FUNCTION AND THERAPY OF A 2.9A STRUCTURE OF BINARY-COMPLEXED ANTITHROMBIN | Descriptor: | PROTEIN (ANTITHROMBIN-III), PROTEIN (PEPTIDE) | Authors: | Skinner, R, Chang, W.S.W, Jin, L, Pei, X.Y, Huntington, J.A, Abrahams, J.P, Carrell, R.W, Lomas, D.A. | Deposit date: | 1998-08-26 | Release date: | 1998-09-02 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Implications for function and therapy of a 2.9 A structure of binary-complexed antithrombin. J.Mol.Biol., 283, 1998
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1D5S
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![BU of 1d5s by Molmil](/molmil-images/mine/1d5s) | CRYSTAL STRUCTURE OF CLEAVED ANTITRYPSIN POLYMER | Descriptor: | P1-ARG ANTITRYPSIN | Authors: | Dunstone, M.A, Dai, W, Whisstock, J.C, Rossjohn, J, Pike, R.N, Feil, S.C, Le Bonneic, B.F, Parker, M.W, Bottomley, S.P. | Deposit date: | 1999-10-11 | Release date: | 2000-04-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Cleaved antitrypsin polymers at atomic resolution. Protein Sci., 9, 2000
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1DVN
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![BU of 1dvn by Molmil](/molmil-images/mine/1dvn) | |