5NBU

Crystal structure of native alpha-1-antitrypsin with seven stabilising mutations

Summary for 5NBU

• Entry DOI: 10.2210/pdb5nbu/pdb
• Descriptor: Alpha-1-antitrypsin, GLYCEROL, OXAMIC ACID, ... (4 entities in total)
• Functional Keywords: serpin, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 42702.60

Authors

Huntington, J.A.,Pomowski, A.,Johnson, D.J.D. (deposition date: 2017-03-02, release date: 2018-03-21, Last modification date: 2024-01-17)

• Primary citation: Johnson, D.J.D.,Pomowski, A.,Huntington, J.A.; CRYSTAL STRUCTURE OF THE Z VARIANT OF ALPHA-1-ANTITRYPSIN REVEALS STRUCTURAL AND DYNAMICAL CHANGES AND SUPPORTS A C-TERMINAL DOMAIN SWAP MECHANISM OF POLYMERIZATION; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.67 Å)