PDB: 501 resultsInfo pagesStatus searchChemie searchBIRD

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7YYN	Mammalian Dicer in the dicing state with pre-miR-15a substrate Descriptor: 59-nt precursor of miR-15a, Isoform 2 of Endoribonuclease Dicer Authors: Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J. Deposit date: 2022-02-18 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (6.21 Å) Cite: Structural and functional basis of mammalian microRNA biogenesis by Dicer. Mol.Cell, 82, 2022
7ZPI	Mammalian Dicer in the "dicing state" with pre-miR-15a substrate Descriptor: 59-nt precursor of miR-15a, Endoribonuclease Dicer Authors: Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J. Deposit date: 2022-04-27 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (5.91 Å) Cite: Structural and functional basis of mammalian microRNA biogenesis by Dicer. Mol.Cell, 82, 2022
1ZBH	3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease Descriptor: 3'-5' exonuclease ERI1, 5'-R(*CP*CP*GP*GP*CP*UP*CP*UP*UP*UP*UP*CP*AP*GP*AP*GP*CP*CP*GP*G)-3', ADENOSINE MONOPHOSPHATE, ... Authors: Cheng, Y, Patel, D.J. Deposit date: 2005-04-08 Release date: 2006-09-26 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural basis for 3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease, a human nuclease that also targets siRNA To be Published
1ZBU	crystal structure of full-length 3'-exonuclease Descriptor: 3'-5' exonuclease ERI1, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION Authors: Cheng, Y, Patel, D.J. Deposit date: 2005-04-08 Release date: 2006-09-19 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.998 Å) Cite: Structural basis for 3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease, a human nuclease that also targets siRNA To be Published
4RBY	First X-ray structure of RNA containing guanosine phosphorodithioate Descriptor: 5'-R(*CP*GP*CP*(2SG)P*AP*AP*UP*UP*AP*GP*CP*G)-3', STRONTIUM ION Authors: Pallan, P.S, Egli, M. Deposit date: 2014-09-13 Release date: 2015-09-16 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.19 Å) Cite: Crystal Structure, Stability and siRNA Activity of Phosphorodithioate-Modified RNAs To be Published
4RC0	X-ray structure of RNA containing guanosine phosphorodithioate Descriptor: 5'-R(*CP*GP*CP*GP*AP*AP*UP*UP*(A2M)P*(2SG)P*CP*G)-3' Authors: Pallan, P.S, Egli, M. Deposit date: 2014-09-13 Release date: 2015-09-16 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.13 Å) Cite: Crystal Structure, Stability and siRNA Activity of Phosphorodithioate-Modified RNAs To be Published
4RBZ	X-ray structure of RNA containing adenosine phosphorodithioate Descriptor: 5'-R(*CP*GP*CP*GP*(A2M)P*(ADS)P*UP*UP*AP*GP*CP*G)-3' Authors: Pallan, P.S, Egli, M. Deposit date: 2014-09-13 Release date: 2015-09-16 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.18 Å) Cite: Crystal Structure, Stability and siRNA Activity of Phosphorodithioate-Modified RNAs To be Published
4O41	Amide linked RNA Descriptor: AMIDE LINKED RNA, STRONTIUM ION Authors: Pallan, P.S, Egli, M. Deposit date: 2013-12-18 Release date: 2014-07-09 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs. Nucleic Acids Res., 42, 2014
2X1O	Gelsolin Nanobody Descriptor: GELSOLIN NANOBODY Authors: Van Den Abbeele, A, Declercq, S, De Ganck, A, De Corte, V, Van Loo, B, Srinivasan, V, Steyaert, J, Van De Kerckhove, J, Gettemans, J. Deposit date: 2010-01-03 Release date: 2011-01-12 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.34 Å) Cite: A Llama-Derived Gelsolin Single-Domain Antibody Blocks Gelsolin-G-Actin Interaction. Cell.Mol.Life Sci., 67, 2010
2X1P	Gelsolin Nanobody Descriptor: GELSOLIN NANOBODY Authors: Van Den Abbeele, A, Declercq, S, De Ganck, A, De Corte, V, Van Loo, B, Srinivasan, V, Steyaert, J, Van De Kerckhove, J, Gettemans, J. Deposit date: 2010-01-03 Release date: 2011-01-12 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.1 Å) Cite: A Llama-Derived Gelsolin Single-Domain Antibody Blocks Gelsolin-G-Actin Interaction. Cell.Mol.Life Sci., 67, 2010
2X1Q	Gelsolin Nanobody Descriptor: GELSOLIN NANOBODY Authors: Van Den Abbeele, A, Declercq, S, De Ganck, A, De Corte, V, Van Loo, B, Srinivasan, V, Steyaert, J, Van De Kerckhove, J, Gettemans, J. Deposit date: 2010-01-03 Release date: 2011-01-12 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.06 Å) Cite: A Llama-Derived Gelsolin Single-Domain Antibody Blocks Gelsolin-G-Actin Interaction. Cell.Mol.Life Sci., 67, 2010
3TIX	Crystal structure of the Chp1-Tas3 complex core Descriptor: CHLORIDE ION, Chromo domain-containing protein 1, POTASSIUM ION, ... Authors: Schalch, T, Joshua-Tor, L. Deposit date: 2011-08-22 Release date: 2011-11-16 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.9001 Å) Cite: The Chp1-Tas3 core is a multifunctional platform critical for gene silencing by RITS. Nat.Struct.Mol.Biol., 18, 2011
6WXQ	Crystal structure of CRISPR-associated transcription factor Csa3 complexed with cA4 Descriptor: CRISPR-associated transcription factor Csa3 (Type I-A), GLYCEROL, cyclic tetraadenylate Authors: Xia, P, Dutta, A, Parashar, V. Deposit date: 2020-05-11 Release date: 2021-11-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural basis of cyclic oligoadenylate binding to the transcription factor Csa3 outlines cross talk between type III and type I CRISPR systems. J.Biol.Chem., 298, 2022
1YTU	Structural basis for 5'-end-specific recognition of the guide RNA strand by the A. fulgidus PIWI protein Descriptor: 5'-R(P*AP*GP*AP*CP*AP*G)-3', 5'-R(P*UP*GP*UP*C)-3', MAGNESIUM ION, ... Authors: Ma, J.B, Yuan, Y.R, Meister, G, Pei, Y, Tuschl, T, Patel, D.J. Deposit date: 2005-02-11 Release date: 2005-04-05 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein. Nature, 434, 2005
4WYQ	Crystal structure of the Dicer-TRBP interface Descriptor: Endoribonuclease Dicer, Poly(UNK), RISC-loading complex subunit TARBP2 Authors: Wilson, R.C, Doudna, J.A. Deposit date: 2014-11-18 Release date: 2014-12-17 Last modified: 2019-12-25 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Dicer-TRBP Complex Formation Ensures Accurate Mammalian MicroRNA Biogenesis. Mol.Cell, 57, 2015
4OLB	Crystal Structure of Human Argonaute2 Bound to Tryptophan Descriptor: 5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*U)-3', Protein argonaute-2, TRYPTOPHAN Authors: Schirle, N.T, MacRae, I.J. Deposit date: 2014-01-23 Release date: 2014-02-05 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.899 Å) Cite: The crystal structure of human Argonaute2. Science, 336, 2012
4OLA	Crystal Structure of Human Argonaute2 Descriptor: 5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*U)-3', ISOPROPYL ALCOHOL, PHENOL, ... Authors: Schirle, N.T, MacRae, I.J. Deposit date: 2014-01-23 Release date: 2014-02-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The crystal structure of human Argonaute2. Science, 336, 2012
5JRE	Crystal structure of NeC3PO in complex with ssDNA. Descriptor: 9-METHYL-9H-PURIN-6-AMINE, ADENINE, NEQ131, ... Authors: Gan, J, Zhang, J. Deposit date: 2016-05-06 Release date: 2016-09-28 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural basis for single-stranded RNA recognition and cleavage by C3PO Nucleic Acids Res., 44, 2016
5JRC	Crystal structure of NeC3PO in complex with ssRNA. Descriptor: CALCIUM ION, NEQ131, ssRNA Authors: Zhang, J, Gan, J. Deposit date: 2016-05-06 Release date: 2016-09-28 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural basis for single-stranded RNA recognition and cleavage by C3PO Nucleic Acids Res., 44, 2016
5JR9	Crystal structure of apo-NeC3PO Descriptor: NEQ131 Authors: Zhang, J, Gan, J. Deposit date: 2016-05-06 Release date: 2016-09-28 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural basis for single-stranded RNA recognition and cleavage by C3PO Nucleic Acids Res., 44, 2016
5W6V	The Structure of human Argonaute-1 in complex with the hook motif of human GW182 Descriptor: Protein argonaute-1, RNA (5'-R(P*AP*AP*UP*AP*UP*UP*AP*AP*AP*A)-3'), Trinucleotide repeat-containing gene 6A protein Authors: Elkayam, E, Faehnle, C.R, Joshua-Tor, L. Deposit date: 2017-06-17 Release date: 2017-07-26 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.828 Å) Cite: Multivalent Recruitment of Human Argonaute by GW182. Mol. Cell, 67, 2017
7Y8P	Crystal structure of 4'-selenoRNA duplex Descriptor: COBALT HEXAMMINE(III), RNA (5'-R(*GP*GP*AP*(IKS)P*(ILK)P*(IKS)P*GP*AP*GP*UP*CP*C)-3') Authors: Kondo, J, Minakawa, N, Ohta, M, Takahashi, H, Tarashima, N. Deposit date: 2022-06-24 Release date: 2023-05-03 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Synthesis and properties of fully-modified 4'-selenoRNA, an endonuclease-resistant RNA analog. Bioorg.Med.Chem., 76, 2022
4TXD	Crystal structure of Thermofilum pendens Csc2 Descriptor: Csc2, ZINC ION Authors: Hrle, A, Conti, E. Deposit date: 2014-07-03 Release date: 2014-08-27 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.818 Å) Cite: Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family. Rna Biol., 11, 2014
3VEM	Structural basis of transcriptional gene silencing mediated by Arabidopsis MOM1 Descriptor: Helicase protein MOM1 Authors: Nishikura, T, Petty, T.J, Halazonetis, T, Paszkowski, J, Thore, S. Deposit date: 2012-01-09 Release date: 2012-03-07 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural Basis of Transcriptional Gene Silencing Mediated by Arabidopsis MOM1. PLOS GENET., 8, 2012
3PJA	Crystal structure of human C3PO complex Descriptor: Translin, Translin-associated protein X Authors: Huang, N, Zhang, H. Deposit date: 2010-11-09 Release date: 2011-05-11 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3 Å) Cite: Structure of C3PO and mechanism of human RISC activation. Nat.Struct.Mol.Biol., 18, 2011

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