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5SYE
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BU of 5sye by Molmil
Near-atomic resolution cryo-EM reconstruction of doubly bound Taxol- and peloruside-stabilized microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kellogg, E.H, Nogales, E.
Deposit date:2016-08-10
Release date:2017-02-01
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures.
J. Mol. Biol., 429, 2017
5AA4
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BU of 5aa4 by Molmil
Crystal structure of MltF from Pseudomonas aeruginosa in complex with cell-wall tetrapeptide
Descriptor: MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE F, [6-[[(2~{R})-1-azanyl-1-oxidanylidene-propan-2-yl]amino]-6-oxidanylidene-5-[[(4~{R})-5-oxidanyl-5-oxidanylidene-4-[[(2~{S})-2-[[(2~{R})-2-oxidanylpropanoyl]amino]propanoyl]amino]pentanoyl]amino]hexyl]azanium
Authors:Dominguez-Gil, T, Acebron, I, Hermoso, J.A.
Deposit date:2015-07-23
Release date:2016-10-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Activation by Allostery in Cell-Wall Remodeling by a Modular Membrane-Bound Lytic Transglycosylase from Pseudomonas aeruginosa.
Structure, 24, 2016
7JUR
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BU of 7jur by Molmil
Crystal Structure of KSR2:MEK1 in complex with AMP-PNP, and allosteric MEK inhibitor Trametinib
Descriptor: Dual specificity mitogen-activated protein kinase kinase 1, Kinase suppressor of Ras 2, MAGNESIUM ION, ...
Authors:Khan, Z.M, Dar, A.C.
Deposit date:2020-08-20
Release date:2020-09-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Structural basis for the action of the drug trametinib at KSR-bound MEK.
Nature, 588, 2020
7JUX
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BU of 7jux by Molmil
Crystal Structure of KSR1:MEK1 in complex with AMP-PNP, and allosteric MEK inhibitor Trametinib
Descriptor: Dual specificity mitogen-activated protein kinase kinase 1, Kinase suppressor of Ras 1, MAGNESIUM ION, ...
Authors:Khan, Z.M, Dar, A.C.
Deposit date:2020-08-20
Release date:2020-09-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:Structural basis for the action of the drug trametinib at KSR-bound MEK.
Nature, 588, 2020
3AS4
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BU of 3as4 by Molmil
MamA AMB-1 C2221
Descriptor: MamA, SULFATE ION
Authors:Zeytuni, N, Davidov, G, Zarivach, R.
Deposit date:2010-12-09
Release date:2011-07-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Self-recognition mechanism of MamA, a magnetosome-associated TPR-containing protein, promotes complex assembly
Proc.Natl.Acad.Sci.USA, 108, 2011
3AS5
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BU of 3as5 by Molmil
MamA AMB-1 P212121
Descriptor: MAGNESIUM ION, MamA
Authors:Zeytuni, N, Davidov, G, Zarivach, R.
Deposit date:2010-12-10
Release date:2011-07-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Self-recognition mechanism of MamA, a magnetosome-associated TPR-containing protein, promotes complex assembly
Proc.Natl.Acad.Sci.USA, 108, 2011
3ASH
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BU of 3ash by Molmil
MamA D159K mutant 1
Descriptor: MamA, SULFATE ION
Authors:Zeytuni, N, Levin, M, Davidov, G, Zarivach, R.
Deposit date:2010-12-11
Release date:2011-07-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Self-recognition mechanism of MamA, a magnetosome-associated TPR-containing protein, promotes complex assembly
Proc.Natl.Acad.Sci.USA, 108, 2011
3ASG
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BU of 3asg by Molmil
MamA D159K mutant 2
Descriptor: MamA
Authors:Zeytuni, N, Levin, M, Davidov, G, Zarivach, R.
Deposit date:2010-12-11
Release date:2011-07-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Self-recognition mechanism of MamA, a magnetosome-associated TPR-containing protein, promotes complex assembly
Proc.Natl.Acad.Sci.USA, 108, 2011
5ZIL
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BU of 5zil by Molmil
Crystal structure of bacteriorhodopsin at 1.29 A resolution
Descriptor: 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, RETINAL
Authors:Hasegawa, N, Jonotsuka, H, Miki, K, Takeda, K.
Deposit date:2018-03-16
Release date:2018-10-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:X-ray structure analysis of bacteriorhodopsin at 1.3 angstrom resolution.
Sci Rep, 8, 2018
7M18
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BU of 7m18 by Molmil
HeLa-tubulin in complex with cryptophycin 1
Descriptor: Cryptophycin 1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Eren, E.
Deposit date:2021-03-12
Release date:2021-09-08
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action.
J.Biol.Chem., 297, 2021
7M20
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BU of 7m20 by Molmil
18-mer HeLa-tubulin rings in complex with Cryptophycin 1
Descriptor: Cryptophycin 1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Eren, E.
Deposit date:2021-03-15
Release date:2021-09-08
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action.
J.Biol.Chem., 297, 2021
7LXB
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BU of 7lxb by Molmil
HeLa-tubulin in complex with cryptophycin 52
Descriptor: Cryptophycin 52, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Eren, E.
Deposit date:2021-03-03
Release date:2021-09-08
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action.
J.Biol.Chem., 297, 2021
5EGL
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BU of 5egl by Molmil
The structural and biochemical characterization of acyl-coa hydrolase from Staphylococcus aureus in complex with Butyryl Coenzyme A, Coenzyme A, and Coenzyme A disulfide
Descriptor: Acyl CoA Hydrolase, Butyryl Coenzyme A, COENZYME A, ...
Authors:Khandokar, Y.B, Srivastava, P.S, Forwood, J.K.
Deposit date:2015-10-27
Release date:2016-11-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structural and biochemical characterization of acyl-coa hydrolase from Staphylococcus aureus
To Be Published
5ZIN
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BU of 5zin by Molmil
Crystal structure of bacteriorhodopsin at 1.27 A resolution
Descriptor: 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, RETINAL
Authors:Hasegawa, N, Jonotsuka, H, Miki, K, Takeda, K.
Deposit date:2018-03-16
Release date:2018-10-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:X-ray structure analysis of bacteriorhodopsin at 1.3 angstrom resolution.
Sci Rep, 8, 2018
5UPN
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BU of 5upn by Molmil
Crystal structure of BhGH81 mutant in complex with laminaro-tetraose
Descriptor: 1,2-ETHANEDIOL, BH0236 protein, PHOSPHATE ION, ...
Authors:Pluvinage, B, Boraston, A.B.
Deposit date:2017-02-03
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The quaternary structure of beta-1,3-glucan contributes to its recognition and hydrolysis by a multimodular family 81 glycoside hydrolase
Structure, 2017
5EC6
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BU of 5ec6 by Molmil
The apo crystal structure of haemoglobin receptor HpuA from Kingella denitrificans
Descriptor: GLYCEROL, HpuA
Authors:Wong, C.T, Garnett, J.A, Hare, S.A.
Deposit date:2015-10-20
Release date:2015-11-04
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural analysis of haemoglobin binding by HpuA from the Neisseriaceae family.
Nat Commun, 6, 2015
7JWL
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BU of 7jwl by Molmil
Crystal Structure of Pseudomonas aeruginosa Penicillin Binding Protein 3 (PAE-PBP3) bound to ETX0462
Descriptor: CHLORIDE ION, ETX0462 (Bound form), Peptidoglycan D,D-transpeptidase FtsI
Authors:Mayclin, S.J, Abendroth, J, Horanyi, P.S, Sylvester, M, Wu, X, Shapiro, A, Moussa, S, Durand-Reville, T.F.
Deposit date:2020-08-25
Release date:2021-05-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Rational design of a new antibiotic class for drug-resistant infections.
Nature, 597, 2021
5ES7
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BU of 5es7 by Molmil
Crystal structure of the F-A domains of the LgrA initiation module soaked with FON, AMPcPP, and valine.
Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, Linear gramicidin synthetase subunit A, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, ...
Authors:Reimer, J.M, Aloise, M.N, Schmeing, T.M.
Deposit date:2015-11-16
Release date:2016-01-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.805 Å)
Cite:Synthetic cycle of the initiation module of a formylating nonribosomal peptide synthetase.
Nature, 529, 2016
5WNJ
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BU of 5wnj by Molmil
Crystal structure of murine receptor-interacting protein kinase 4 (Ripk4) D143N in complex with lestaurtinib
Descriptor: CHLORIDE ION, Lestaurtinib, Receptor-interacting serine/threonine-protein kinase 4
Authors:Huang, C.S, Hymowitz, S.G.
Deposit date:2017-08-01
Release date:2018-05-09
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity.
Structure, 26, 2018
5Z8K
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BU of 5z8k by Molmil
Crystal structure of an aminotransferase in complex with product-1
Descriptor: (1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside, C-6' aminotransferase, PYRIDOXAL-5'-PHOSPHATE
Authors:Hong, S.K, Cha, S.S.
Deposit date:2018-01-31
Release date:2019-01-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.759 Å)
Cite:Complete reconstitution of the diverse pathways of gentamicin B biosynthesis.
Nat. Chem. Biol., 15, 2019
5CSY
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BU of 5csy by Molmil
Disproportionating enzyme 1 from Arabidopsis - acarbose soak
Descriptor: 1,2-ETHANEDIOL, 4-alpha-glucanotransferase DPE1, chloroplastic/amyloplastic, ...
Authors:O'Neill, E.C, Stevenson, C.E.M, Tantanarat, K, Latousakis, D, Donaldson, M.I, Rejzek, M, Limpaseni, T, Smith, A.M, Field, R.A, Lawson, D.M.
Deposit date:2015-07-23
Release date:2015-11-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Dissection of the Maltodextrin Disproportionation Cycle of the Arabidopsis Plastidial Disproportionating Enzyme 1 (DPE1).
J.Biol.Chem., 290, 2015
5SYC
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BU of 5syc by Molmil
Near-atomic resolution cryo-EM reconstruction of peloruside-stabilized microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kellogg, E.H, Nogales, E.
Deposit date:2016-08-10
Release date:2017-02-01
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures.
J. Mol. Biol., 429, 2017
5UFS
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BU of 5ufs by Molmil
X-Ray Crystal Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with triamcinolone acetonide and SHP coregulator fragment
Descriptor: Ancestral Glucocorticoid Receptor2, SHP NR Box 1 Peptide, Triamcinolone acetonide
Authors:Weikum, E.R, Ortlund, E.A.
Deposit date:2017-01-05
Release date:2017-04-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.118 Å)
Cite:Structural Analysis of the Glucocorticoid Receptor Ligand-Binding Domain in Complex with Triamcinolone Acetonide and a Fragment of the Atypical Coregulator, Small Heterodimer Partner.
Mol. Pharmacol., 92, 2017
5EDE
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BU of 5ede by Molmil
human PDE10A in complex with 1-(4-Chloro-phenyl)-3-methyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid (tetrahydro-furan-2-ylmethyl)-amide at 2.2A
Descriptor: 1-(4-chlorophenyl)-3-methyl-~{N}-[[(2~{R})-oxolan-2-yl]methyl]thieno[2,3-c]pyrazole-5-carboxamide, GLYCEROL, MAGNESIUM ION, ...
Authors:Joseph, C, Rudolph, M.G.
Deposit date:2015-10-21
Release date:2016-03-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Real-World Perspective on Molecular Design.
J.Med.Chem., 59, 2016
5ZIM
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BU of 5zim by Molmil
Crystal structure of bacteriorhodopsin at 1.25 A resolution
Descriptor: 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, RETINAL
Authors:Hasegawa, N, Jonotsuka, H, Miki, K, Takeda, K.
Deposit date:2018-03-16
Release date:2018-10-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:X-ray structure analysis of bacteriorhodopsin at 1.3 angstrom resolution.
Sci Rep, 8, 2018

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