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1Q94
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BU of 1q94 by Molmil
Structures of HLA-A*1101 in complex with immunodominant nonamer and decamer HIV-1 epitopes clearly reveal the presence of a middle anchor residue
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-11 alpha chain, ...
Authors:Li, L, McNicholl, J.M, Bouvier, M.
Deposit date:2003-08-22
Release date:2004-06-01
Last modified:2020-02-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of HLA-A*1101 complexed with immunodominant nonamer and decamer HIV-1 epitopes clearly reveal the presence of a middle, secondary anchor residue.
J.Immunol., 172, 2004
3BXN
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BU of 3bxn by Molmil
The high resolution crystal structure of HLA-B*1402 complexed with a Cathepsin A signal sequence peptide, pCatA
Descriptor: Cathepsin A signal sequence octapeptide, GLYCEROL, HLA-B*1402 extracellular domain, ...
Authors:Kumar, P, Vahedi-Faridi, A, Saenger, W, Uchanska-Ziegler, B, Ziegler, A.
Deposit date:2008-01-14
Release date:2009-02-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.864 Å)
Cite:Structural basis for T cell alloreactivity among three HLA-B14 and HLA-B27 antigens
J.Biol.Chem., 284, 2009
1PY4
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BU of 1py4 by Molmil
Beta2 microglobulin mutant H31Y displays hints for amyloid formations
Descriptor: Beta-2-microglobulin precursor
Authors:Rosano, C, Zuccotti, S, Mangione, P, Giorgetti, S, Bellotti, V, Pettirossi, F, Corazza, A, Viglino, P, Esposito, G, Bolognesi, M.
Deposit date:2003-07-08
Release date:2004-05-04
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:beta2-microglobulin H31Y variant 3D structure highlights the protein natural propensity towards intermolecular aggregation
J.Mol.Biol., 335, 2004
3BZE
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BU of 3bze by Molmil
The human non-classical major histocompatibility complex molecule HLA-E
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain E, ...
Authors:Hoare, H.L, Sullivan, L.C, Ely, L.K, Beddoe, T, Henderson, K.N, Lin, J, Clements, C.S, Reid, H.H, Brooks, A.G, Rossjohn, J.
Deposit date:2008-01-17
Release date:2008-04-29
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Subtle changes in peptide conformation profoundly affect recognition of the non-classical MHC class I molecule HLA-E by the CD94-NKG2 natural killer cell receptors
J.Mol.Biol., 377, 2008
3AM8
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BU of 3am8 by Molmil
Crystal Structure of a Human Major Histocompatibilty complex
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain E, ...
Authors:Chacko, J, Clements, C, Rossjohn, J.
Deposit date:2010-08-18
Release date:2011-08-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of a Human Major Histocompatibility complex
To be Published
1QLF
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BU of 1qlf by Molmil
MHC CLASS I H-2DB COMPLEXED WITH GLYCOPEPTIDE K3G
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, HUMAN BETA-2-MICROGLOBULIN, ...
Authors:Tormo, J, Jones, E.Y.
Deposit date:1999-08-30
Release date:1999-09-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal Structures of Two H-2Db/Glycopeptide Complexes Suggest a Molecular Basis for Ctl Cross-Reactivity
Immunity, 10, 1999
3BWA
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BU of 3bwa by Molmil
Crystal Structure of HLA B*3508 in complex with a HCMV 8-mer peptide from the pp65 protein
Descriptor: Beta-2-microglobulin, FPT peptide from 65 kDa lower matrix phosphoprotein, HLA class I histocompatibility antigen, ...
Authors:Wynn, K.K, Marland, Z, Cooper, L, Silins, S.L, Gras, S, Archbold, J.K, Tynan, F.E, Miles, J.J, McCluskey, J, Burrows, S.R, Rossjohn, J, Khanna, R.
Deposit date:2008-01-08
Release date:2008-04-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection
Blood, 111, 2008
1QRN
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BU of 1qrn by Molmil
CRYSTAL STRUCTURE OF HUMAN A6 TCR COMPLEXED WITH HLA-A2 BOUND TO ALTERED HTLV-1 TAX PEPTIDE P6A
Descriptor: BETA-2 MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, ...
Authors:Ding, Y.H, Baker, B.M, Garboczi, D.N, Biddison, W.E, Wiley, D.C.
Deposit date:1999-06-14
Release date:1999-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical.
Immunity, 11, 1999
3C9N
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BU of 3c9n by Molmil
Crystal Structure of a SARS Corona Virus Derived Peptide Bound to the Human Major Histocompatibility Complex Class I molecule HLA-B*1501
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Roder, G.A, Kristensen, O, Kastrup, J.S, Buus, S, Gajhede, M.
Deposit date:2008-02-18
Release date:2008-02-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structure of a SARS coronavirus-derived peptide bound to the human major histocompatibility complex class I molecule HLA-B*1501.
ACTA CRYSTALLOGR.,SECT.F, 64, 2008
3CDG
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BU of 3cdg by Molmil
Human CD94/NKG2A in complex with HLA-E
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain E, ...
Authors:Petrie, E.J, Clements, C.S, Lin, J, Sullivan, L.C, Johnson, D, Huyton, T, Heroux, A, Hoare, H.L, Beddoe, T, Reid, H.H, Wilce, M.C.J, Brooks, A.G, Rossjohn, J.
Deposit date:2008-02-26
Release date:2008-04-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence
J.Exp.Med., 205, 2008
1QVO
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BU of 1qvo by Molmil
STRUCTURES OF HLA-A*1101 IN COMPLEX WITH IMMUNODOMINANT NONAMER AND DECAMER HIV-1 EPITOPES CLEARLY REVEAL THE PRESENCE OF A MIDDLE ANCHOR RESIDUE
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-11 alpha chain, ...
Authors:Li, L, McNicholl, J.M, Bouvier, M.
Deposit date:2003-08-28
Release date:2004-06-01
Last modified:2020-02-19
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structures of HLA-A*1101 complexed with immunodominant nonamer and decamer HIV-1 epitopes clearly reveal the presence of a middle, secondary anchor residue.
J.Immunol., 172, 2004
2O69
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BU of 2o69 by Molmil
Crystal Structure of Haemophilus influenzae N193L mutant FbpA
Descriptor: FE (III) ION, Iron-utilization periplasmic protein
Authors:Shouldice, S.R, Tari, L.W.
Deposit date:2006-12-07
Release date:2007-04-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:The role of the synergistic phosphate anion in iron transport by the periplasmic iron-binding protein from Haemophilus influenzae.
Biochem.J., 403, 2007
1QEW
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BU of 1qew by Molmil
HUMAN CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A 0201) COMPLEX WITH A NONAMERIC PEPTIDE FROM MELANOMA-ASSOCIATED ANTIGEN 3 (RESIDUES 271-279)
Descriptor: PROTEIN (BETA-2-MICROGLOBULIN), PROTEIN (HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-35 B* 3501 ALPHA CHAIN), ...
Authors:Orth, P, Alings, C, Saenger, W, Ziegler, A.
Deposit date:1999-04-02
Release date:2003-11-18
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:HUMAN CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A 0201) COMPLEX WITH A NONAMERIC PEPTIDE FROM MELANOMA-ASSOCIATED ANTIGEN 3 (RESIDUES 271-279)
To be Published
3D18
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BU of 3d18 by Molmil
Crystal structure of HLA-B*2709 complexed with a variant of the latent membrane protein 2 peptide (LMP2(L)) of epstein-barr virus
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-2-microglobulin, ...
Authors:Beltrami, A, Gabdulkhakov, A, Rossmann, M, Ziegler, A, Uchanska-Ziegler, B, Saenger, W.
Deposit date:2008-05-05
Release date:2009-05-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structure of HLA-B*2709 complexed with a variant of the latent membrane protein 2 peptide (LMP2(L)) of epstein-barr virus
To be Published
3D2U
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BU of 3d2u by Molmil
Structure of UL18, a Peptide-Binding Viral MHC Mimic, Bound to a Host Inhibitory Receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Actin, Beta-2-microglobulin, ...
Authors:Yang, Z, Bjorkman, P.J.
Deposit date:2008-05-08
Release date:2008-07-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structure of UL18, a peptide-binding viral MHC mimic, bound to a host inhibitory receptor
Proc.Natl.Acad.Sci.Usa, 105, 2008
5XOV
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BU of 5xov by Molmil
Crystal structure of peptide-HLA-A24 bound to S19-2 V-delta/V-beta TCR
Descriptor: Beta-2-microglobulin, HIV-1 Nef138-10 peptide, HLA class I histocompatibility antigen, ...
Authors:Shi, Y, Qi, J, Gao, G.F.
Deposit date:2017-05-31
Release date:2017-06-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.684 Å)
Cite:Conserved V delta 1 Binding Geometry in a Setting of Locus-Disparate pHLA Recognition by delta / alpha beta T Cell Receptors (TCRs): Insight into Recognition of HIV Peptides by TCRs.
J. Virol., 91, 2017
1EFX
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BU of 1efx by Molmil
STRUCTURE OF A COMPLEX BETWEEN THE HUMAN NATURAL KILLER CELL RECEPTOR KIR2DL2 AND A CLASS I MHC LIGAND HLA-CW3
Descriptor: BETA-2-MICROGLOBULIN, HLA-CW3 (HEAVY CHAIN), NATURAL KILLER CELL RECEPTOR KIR2DL2, ...
Authors:Boyington, J.C, Motyka, S.A, Schuck, P, Brooks, A.G, Sun, P.D.
Deposit date:2000-02-10
Release date:2000-06-14
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand.
Nature, 405, 2000
5XOS
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BU of 5xos by Molmil
Crystal structure of HLA-B35 in complex with a pepetide antigen
Descriptor: An HIV reverse transcriptase epitope, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Shi, Y, Qi, J, Gao, G.F.
Deposit date:2017-05-31
Release date:2017-06-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.697 Å)
Cite:Conserved V delta 1 Binding Geometry in a Setting of Locus-Disparate pHLA Recognition by delta / alpha beta T Cell Receptors (TCRs): Insight into Recognition of HIV Peptides by TCRs.
J. Virol., 91, 2017
1EEZ
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BU of 1eez by Molmil
Crystal Structure Determination of HLA-A2.1 Complexed to GP2 Peptide Variant(I2L/V5L)
Descriptor: BETA-2-MICROGLOBULIN (LIGHT CHAIN), GP2 PEPTIDE, HLA-A2.1 MHC CLASS I (HEAVY CHAIN)
Authors:Sharma, A.K, Kuhns, J.J, Collins, E.J.
Deposit date:2000-02-04
Release date:2003-06-10
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Class I major histocompatibility complex anchor substitutions alter the conformation of T cell receptor contacts.
J.Biol.Chem., 276, 2001
1EXU
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BU of 1exu by Molmil
CRYSTAL STRUCTURE OF THE HUMAN MHC-RELATED FC RECEPTOR
Descriptor: BETA-2-MICROGLOBULIN, BETA-MERCAPTOETHANOL, IGG RECEPTOR FCRN LARGE SUBUNIT P51
Authors:West Jr, A.P, Bjorkman, P.J.
Deposit date:2000-05-04
Release date:2000-08-10
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure and immunoglobulin G binding properties of the human major histocompatibility complex-related Fc receptor(,).
Biochemistry, 39, 2000
5WJL
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BU of 5wjl by Molmil
Crystal Structure of HLA-A*11:01 with GTS1 peptide
Descriptor: Beta-2-microglobulin, CHLORIDE ION, GTS1 peptide, ...
Authors:Gras, S, Rossjohn, J.
Deposit date:2017-07-23
Release date:2017-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8(+) T cell response.
Nat. Immunol., 18, 2017
5WMQ
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BU of 5wmq by Molmil
Crystal Structure of HLA-B8 in complex with ELR, an Influenza A virus peptide
Descriptor: Beta-2-microglobulin, ELR peptide from IAV, HLA class I histocompatibility antigen, ...
Authors:Gras, S, Rossjohn, J.
Deposit date:2017-07-31
Release date:2018-06-06
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Inability To Detect Cross-Reactive Memory T Cells Challenges the Frequency of Heterologous Immunity among Common Viruses.
J. Immunol., 200, 2018
5W1W
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BU of 5w1w by Molmil
Structure of the HLA-E-VMAPRTLVL/GF4 TCR complex
Descriptor: Beta-2-microglobulin, GF4 T cell receptor alpha chain, GF4 T cell receptor beta chain, ...
Authors:Gras, S, Walpole, N, Farenc, C, Rossjohn, J.
Deposit date:2017-06-05
Release date:2017-10-04
Last modified:2018-01-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct alpha beta T cell receptors.
J. Biol. Chem., 292, 2017
5W69
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HLA-C*06:02 presenting ARFNDLRFV
Descriptor: ALA-ARG-PHE-ASN-ASP-LEU-ARG-PHE-VAL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Mobbs, J.I, Vivian, J.P, Rossjohn, J.
Deposit date:2017-06-16
Release date:2017-08-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The molecular basis for peptide repertoire selection in the human leucocyte antigen (HLA) C*06:02 molecule.
J. Biol. Chem., 292, 2017
5WSH
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BU of 5wsh by Molmil
Structure of HLA-A2 P130
Descriptor: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, GLY-VAL-TRP-ILE-ARG-THR-PRO-THR-ALA, ...
Authors:Zhang, Y, Wu, Y, Qi, J, Liu, J, Gao, G.F, Meng, S.
Deposit date:2016-12-07
Release date:2017-12-20
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:CD8+T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress.
J. Virol., 92, 2018

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