PDB: 46200 resultsInfo pagesStatus searchChemie searchBIRD

---

8CEO	Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Wang, H, Cramer, P. Deposit date: 2023-02-02 Release date: 2023-03-08 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain. Proc.Natl.Acad.Sci.USA, 120, 2023
7CHW	Cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) Descriptor: DNA (63-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Lin, W, Feng, Y. Deposit date: 2020-07-06 Release date: 2020-08-12 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.58 Å) Cite: Structural basis for transcription inhibition by E. coli SspA Nucleic Acids Res., 2020
4MEY	Crystal structure of Escherichia coli RNA polymerase holoenzyme Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Feng, Y, Zhang, Y, Arnold, E, Ebright, R.H. Deposit date: 2013-08-27 Release date: 2014-05-21 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.948 Å) Cite: Transcription inhibition by the depsipeptide antibiotic salinamide A. Elife, 3, 2014
6P19	Q21 transcription antitermination complex: loaded complex Descriptor: DNA (123-MER) fragment carrying phage-21 pR' promoter, pause element, and transcribed region, ... Authors: Yin, Z, Ebright, R.H. Deposit date: 2019-05-19 Release date: 2019-06-26 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural basis of Q-dependent antitermination. Proc.Natl.Acad.Sci.USA, 116, 2019
9C0I	Structure of the DRT2 reverse transcriptase in complex with its non-coding RNA Descriptor: DNA primer, DRT2 ncRNA, MAGNESIUM ION, ... Authors: Wilkinson, M.E, Zhang, F. Deposit date: 2024-05-25 Release date: 2024-09-04 Last modified: 2024-09-18 Method: ELECTRON MICROSCOPY (2.91 Å) Cite: Phage-triggered reverse transcription assembles a toxic repetitive gene from a noncoding RNA. Science, 2024
4WA8	Methanopyrus Kandleri FEN-1 nuclease Descriptor: CHLORIDE ION, Flap endonuclease 1 Authors: Shah, S, Dunten, P, Horton, N.C. Deposit date: 2014-08-28 Release date: 2014-11-12 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure and specificity of FEN-1 from Methanopyrus kandleri. Proteins, 83, 2015
9C7B	Crystal structure of R150H neurodevelopmental disease-associated U2AF2 variant Descriptor: DNA/RNA (5'-R(P*UP*U)-D(P*U)-R(P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit Authors: Maji, D, Jenkins, J.L, Kielkopf, C.L. Deposit date: 2024-06-10 Release date: 2024-10-02 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Recurrent neurodevelopmentally-associated variants of the pre-mRNA splicing factor U2AF2 alter RNA binding affinities and interactions To Be Published
6LGQ	The crystal complex structure of histidine kinase and response regulator Descriptor: DNA-binding response regulator, Histidine kinase KdpD Authors: Ming, Q.X. Deposit date: 2019-12-05 Release date: 2020-12-09 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3 Å) Cite: The crystal complex structure of histidine kinase and response regulator To Be Published
6FBV	Single particle cryo em structure of Mycobacterium tuberculosis RNA polymerase in complex with Fidaxomicin Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Das, K, Lin, W, Ebright, E. Deposit date: 2017-12-19 Release date: 2018-02-28 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.52 Å) Cite: Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3). Mol. Cell, 70, 2018
8F3C	Cryo-EM consensus structure of Escherichia coli que-PEC (paused elongation complex) RNA Polymerase minus preQ1 ligand Descriptor: DNA (38-MER), DNA (39-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Porta, J.C, Chauvier, A, Deb, I, Ellinger, E, Frank, A.T, Meze, K, Ohi, M.D, Walter, N.G. Deposit date: 2022-11-09 Release date: 2023-06-21 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis for control of bacterial RNA polymerase pausing by a riboswitch and its ligand. Nat.Struct.Mol.Biol., 30, 2023
8FIX	Cryo-EM structure of E. coli RNA polymerase backtracked elongation complex harboring a terminal mismatch Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Florez Ariza, A, Wee, L, Tong, A, Canari, C, Grob, P, Nogales, E, Bustamante, C. Deposit date: 2022-12-17 Release date: 2023-03-29 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery. Cell, 186, 2023
8XMD	Pre-translocated Pol IV transcription elongation complex Descriptor: DNA-directed RNA polymerase IV subunit 1, DNA-directed RNA polymerase IV subunit 7, DNA-directed RNA polymerases II and IV subunit 5A, ... Authors: Huang, K, Fang, C.L, Zhang, Y. Deposit date: 2023-12-27 Release date: 2024-07-24 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Transcription of the Plant RNA polymerase IV is prone to backtracking To Be Published
8XME	Backtracked Pol IV transcription elongation complex Descriptor: DNA-directed RNA polymerase IV subunit 1, DNA-directed RNA polymerase IV subunit 7, DNA-directed RNA polymerases II and IV subunit 5A, ... Authors: Huang, K, Fang, C.L, Zhang, Y. Deposit date: 2023-12-27 Release date: 2024-07-24 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Transcription of the Plant RNA polymerase IV is prone to backtracking To Be Published
8XMB	NTP-bound Pol IV transcription elongation complex Descriptor: DNA-directed RNA polymerase IV subunit 1, DNA-directed RNA polymerase IV subunit 7, DNA-directed RNA polymerases II and IV subunit 5A, ... Authors: Huang, K, Fang, C.L, Zhang, Y. Deposit date: 2023-12-27 Release date: 2024-07-24 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Transcription of the Plant RNA polymerase IV is prone to backtracking To Be Published
8G00	Cryo-EM structure of 3DVA component 0 of Escherichia coli que-PEC (paused elongation complex) RNA Polymerase minus preQ1 ligand Descriptor: DNA (31-MER), DNA (39-mer), DNA-directed RNA polymerase subunit alpha, ... Authors: Porta, J.C, Chauvier, A, Deb, I, Ellinger, E, Frank, A.T, Meze, K, Ohi, M.D, Walter, N.G. Deposit date: 2023-01-31 Release date: 2023-06-21 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis for control of bacterial RNA polymerase pausing by a riboswitch and its ligand. Nat.Struct.Mol.Biol., 30, 2023
6JCX	Mycobacterium tuberculosis transcription initiation complex with ECF sigma factor sigma H and 6nt RNA Descriptor: DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Li, L, Zhang, Y. Deposit date: 2019-01-30 Release date: 2019-05-29 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.903 Å) Cite: Structures and mechanism of transcription initiation by bacterial ECF factors. Nucleic Acids Res., 47, 2019
6HLR	Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP (core focused) Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Tafur, L, Sadian, Y, Weis, F, Muller, C.W. Deposit date: 2018-09-11 Release date: 2019-04-03 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.18 Å) Cite: The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
6HLS	Yeast apo RNA polymerase I* Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Tafur, L, Sadian, Y, Weis, F, Muller, C.W. Deposit date: 2018-09-11 Release date: 2019-04-03 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.21 Å) Cite: The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
6HLQ	Yeast RNA polymerase I* elongation complex bound to nucleotide analog GMPCPP Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Tafur, L, Sadian, Y, Weis, F, Muller, C.W. Deposit date: 2018-09-11 Release date: 2019-04-03 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.18 Å) Cite: The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
9C4C	The structure of two MntR dimers bound to the native mnep promoter sequence Descriptor: DNA (38-MER), DNA (39-MER), HTH-type transcriptional regulator MntR, ... Authors: Shi, H, Fu, Y, Glasfeld, A, Ahuja, S. Deposit date: 2024-06-04 Release date: 2024-08-14 Method: ELECTRON MICROSCOPY (3.09 Å) Cite: The structure of two MntR dimers bound to the native mnep promoter sequence. To Be Published
9BAZ	CryoEM structure of DIM2-HP1 complex Descriptor: DNA (cytosine-5-)-methyltransferase, Heterochromatin protein one, S-ADENOSYL-L-HOMOCYSTEINE, ... Authors: Song, J, Shao, Z. Deposit date: 2024-04-05 Release date: 2024-07-24 Method: ELECTRON MICROSCOPY (2.76 Å) Cite: CryoEM structure of DIM2-HP1 complex To Be Published
8J9Z	cryo-EM structure of viral topoisomerase in conformation 2 Descriptor: DNA topoisomerase 2 Authors: Deng, Z. Deposit date: 2023-05-05 Release date: 2023-08-16 Last modified: 2023-11-29 Method: ELECTRON MICROSCOPY (3.13 Å) Cite: Cryo-EM structures of African swine fever virus topoisomerase. Mbio, 14, 2023
8J9Y	cryo-EM structure of viral topoisomerase in conformation 1 Descriptor: DNA topoisomerase 2 Authors: Deng, Z. Deposit date: 2023-05-05 Release date: 2023-08-16 Last modified: 2023-11-29 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Cryo-EM structures of African swine fever virus topoisomerase. Mbio, 14, 2023
6DG0	MEC-8 C-terminal RRM domain bound to AGCACA Descriptor: DNA (5'-D(*AP*GP*CP*AP*CP*A)-3'), Mec-8 protein Authors: Mackereth, C.D, Soufari, H. Deposit date: 2018-05-16 Release date: 2019-08-21 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.457 Å) Cite: Structure of MEC-8 RRM2 in complex with AGCACA To Be Published
4JKR	Crystal Structure of E. coli RNA Polymerase in complex with ppGpp Descriptor: DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA', DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Zuo, Y, Wang, Y, Steitz, T.A. Deposit date: 2013-03-11 Release date: 2013-05-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (4.2 Å) Cite: The mechanism of E. coli RNA polymerase regulation by ppGpp is suggested by the structure of their complex. Mol.Cell, 50, 2013

<631632633634635636637638639640641642643644645646>