5I8F
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![BU of 5i8f by Molmil](/molmil-images/mine/5i8f) | Crystal structure of St. John's wort Hyp-1 protein in complex with melatonin | Descriptor: | GLYCEROL, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide, Phenolic oxidative coupling protein, ... | Authors: | Sliwiak, J, Dauter, Z, Jaskolski, M. | Deposit date: | 2016-02-18 | Release date: | 2016-05-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Crystal Structure of Hyp-1, a Hypericum perforatum PR-10 Protein, in Complex with Melatonin. Front Plant Sci, 7, 2016
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6Y3Q
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![BU of 6y3q by Molmil](/molmil-images/mine/6y3q) | Streptavidin mutant S112R_K121E with a biotC5-1 cofactor - an artificial iron hydroxylase | Descriptor: | SULFATE ION, Streptavidin, biotC5-1 cofactor | Authors: | Serrano-Plana, J, Rumo, C, Rebelein, J.G, Peterson, R.L, Barnet, M, Ward, T.R. | Deposit date: | 2020-02-18 | Release date: | 2020-07-01 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Enantioselective Hydroxylation of Benzylic C(sp3)-H Bonds by an Artificial Iron Hydroxylase Based on the Biotin-Streptavidin Technology. J.Am.Chem.Soc., 142, 2020
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2GCI
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![BU of 2gci by Molmil](/molmil-images/mine/2gci) | The 1,1-proton transfer reaction mechanism by alpha-methylacyl-CoA racemase is catalyzed by an asparte/histidine pair and involves a smooth, methionine-rich surface for binding the fatty acyl moiety | Descriptor: | (R)-2-METHYLMYRISTOYL-COENZYME A, GLYCEROL, probable alpha-methylacyl-CoA racemase MCR | Authors: | Bhaumik, P, Wierenga, R.K. | Deposit date: | 2006-03-14 | Release date: | 2007-02-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The Catalysis of the 1,1-Proton Transfer by alpha-Methyl-acyl-CoA Racemase Is Coupled to a Movement of the Fatty Acyl Moiety Over a Hydrophobic, Methionine-rich Surface J.Mol.Biol., 367, 2007
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6LMI
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![BU of 6lmi by Molmil](/molmil-images/mine/6lmi) | Crystal structure of HIV-1 integrase catalytic core domain in complex with 2-(tert-butoxy)-2-[3-(3,4-dihydro-2H-1-benzopyran-6-yl)-6-methanesulfonamido-2,3',4',5-tetramethyl-[1,1'-biphenyl]-4-yl]acetic acid | Descriptor: | (2S)-2-[2-(3,4-dihydro-2H-chromen-6-yl)-4-(3,4-dimethylphenyl)-3,6-dimethyl-5-(methylsulfonylamino)phenyl]-2-[(2-methylpropan-2-yl)oxy]ethanoic acid, 1,2-ETHANEDIOL, Integrase catalytic, ... | Authors: | Sugiyama, S, Iwaki, T, Tamura, Y, Tomita, K, Matsuoka, E, Arita, S, Seki, T, Yoshinaga, T, Kawasuji, T. | Deposit date: | 2019-12-25 | Release date: | 2020-09-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Discovery of novel integrase-LEDGF/p75 allosteric inhibitors based on a benzene scaffold. Bioorg.Med.Chem., 28, 2020
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5AJU
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![BU of 5aju by Molmil](/molmil-images/mine/5aju) | |
6LMQ
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![BU of 6lmq by Molmil](/molmil-images/mine/6lmq) | Crystal structure of HIV-1 integrase catalytic core domain in complex with 2-(tert-butoxy)-2-[3-(3,4-dihydro-2H-1,4-benzoxazin-6-yl)-6-methanesulfonamido-2,3',4',5-tetramethyl-[1,1'-biphenyl]-4-yl]acetic acid | Descriptor: | (2S)-2-[2-(3,4-dihydro-2H-1,4-benzoxazin-6-yl)-4-(3,4-dimethylphenyl)-3,6-dimethyl-5-(methylsulfonylamino)phenyl]-2-[(2-methylpropan-2-yl)oxy]ethanoic acid, Integrase catalytic, SULFATE ION, ... | Authors: | Sugiyama, S, Iwaki, T, Tamura, Y, Tomita, K, Matsuoka, E, Arita, S, Seki, T, Yoshinaga, T, Kawasuji, T. | Deposit date: | 2019-12-26 | Release date: | 2020-09-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Discovery of novel integrase-LEDGF/p75 allosteric inhibitors based on a benzene scaffold. Bioorg.Med.Chem., 28, 2020
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7ZT4
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![BU of 7zt4 by Molmil](/molmil-images/mine/7zt4) | Structure of E8 TCR in complex with human MR1 bound to 6FP | Descriptor: | 2-azanyl-6-methyl-3~{H}-pteridin-4-one, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ... | Authors: | Karuppiah, V, Robinson, R.A. | Deposit date: | 2022-05-09 | Release date: | 2023-06-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220, 2023
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7ZT9
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![BU of 7zt9 by Molmil](/molmil-images/mine/7zt9) | Structure of E8 TCR in complex in human MR1 bound to 4FBA | Descriptor: | 1,2-ETHANEDIOL, 4-METHYLBENZOIC ACID, Beta-2-microglobulin, ... | Authors: | Karuppiah, V, Srikannathasan, V, Robinson, R.A. | Deposit date: | 2022-05-09 | Release date: | 2023-06-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220, 2023
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7ZT3
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![BU of 7zt3 by Molmil](/molmil-images/mine/7zt3) | Structure of E8 TCR in complex in human MR1 K43A | Descriptor: | Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, TCR alpha, ... | Authors: | Karuppiah, V, Srikannathasan, V, Robinson, R.A. | Deposit date: | 2022-05-09 | Release date: | 2023-06-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220, 2023
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7ZT5
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![BU of 7zt5 by Molmil](/molmil-images/mine/7zt5) | Structure of E8 TCR in complex in human MR1 bound to 3FSA | Descriptor: | 3-methanoyl-2-oxidanyl-benzoic acid, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ... | Authors: | Karuppiah, V, Robinson, R.A. | Deposit date: | 2022-05-09 | Release date: | 2023-06-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220, 2023
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7ZT7
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![BU of 7zt7 by Molmil](/molmil-images/mine/7zt7) | |
6Y25
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![BU of 6y25 by Molmil](/molmil-images/mine/6y25) | Streptavidin mutant S112R,K121E with a biotC4-1 cofactor - an artificial iron hydroxylase | Descriptor: | Streptavidin, biotC4-1 cofactor | Authors: | Serrano-Plana, J, Rumo, C, Rebelein, J.G, Peterson, R.L, Barnet, M, Ward, T.R. | Deposit date: | 2020-02-14 | Release date: | 2020-07-01 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Enantioselective Hydroxylation of Benzylic C(sp3)-H Bonds by an Artificial Iron Hydroxylase Based on the Biotin-Streptavidin Technology. J.Am.Chem.Soc., 142, 2020
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6Y34
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![BU of 6y34 by Molmil](/molmil-images/mine/6y34) | Streptavidin wildtype with a biotC5-1 cofactor - an artificial iron hydroxylase | Descriptor: | GLYCEROL, Streptavidin, biotC5-1 cofactor | Authors: | Serrano-Plana, J, Rumo, C, Rebelein, J.G, Peterson, R.L, Barnet, M, Ward, T.R. | Deposit date: | 2020-02-17 | Release date: | 2020-07-01 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.307 Å) | Cite: | Enantioselective Hydroxylation of Benzylic C(sp3)-H Bonds by an Artificial Iron Hydroxylase Based on the Biotin-Streptavidin Technology. J.Am.Chem.Soc., 142, 2020
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7ZNO
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![BU of 7zno by Molmil](/molmil-images/mine/7zno) | |
2H0F
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![BU of 2h0f by Molmil](/molmil-images/mine/2h0f) | Crystal Structure of PucM in the presence of 8-azaxanthine | Descriptor: | 8-AZAXANTHINE, Transthyretin-like protein pucM | Authors: | Rhee, S. | Deposit date: | 2006-05-15 | Release date: | 2006-06-27 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and functional analysis of PucM, a hydrolase in the ureide pathway and a member of the transthyretin-related protein family. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2H0E
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![BU of 2h0e by Molmil](/molmil-images/mine/2h0e) | Crystal Structure of PucM in the absence of substrate | Descriptor: | GLYCEROL, Transthyretin-like protein pucM | Authors: | Rhee, S. | Deposit date: | 2006-05-14 | Release date: | 2006-06-27 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and functional analysis of PucM, a hydrolase in the ureide pathway and a member of the transthyretin-related protein family. Proc.Natl.Acad.Sci.Usa, 103, 2006
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6LX1
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![BU of 6lx1 by Molmil](/molmil-images/mine/6lx1) | Potato D-enzyme complexed with Acarbose | Descriptor: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-1,5-anhydro-D-glucitol, 4-alpha-glucanotransferase, chloroplastic/amyloplastic, ... | Authors: | Unno, H, Imamura, K. | Deposit date: | 2020-02-10 | Release date: | 2020-08-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Structural analysis and reaction mechanism of the disproportionating enzyme (D-enzyme) from potato. Protein Sci., 29, 2020
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1RKX
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![BU of 1rkx by Molmil](/molmil-images/mine/1rkx) | Crystal Structure at 1.8 Angstrom of CDP-D-glucose 4,6-dehydratase from Yersinia pseudotuberculosis | Descriptor: | CDP-glucose-4,6-dehydratase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Vogan, E.M, Bellamacina, C, He, X, Liu, H.W, Ringe, D, Petsko, G.A. | Deposit date: | 2003-11-23 | Release date: | 2004-03-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure at 1.8 A Resolution of CDP-d-Glucose 4,6-Dehydratase from Yersinia pseudotuberculosis Biochemistry, 43, 2004
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6B85
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![BU of 6b85 by Molmil](/molmil-images/mine/6b85) | Crystal structure of transmembrane protein TMHC4_R | Descriptor: | TMHC4_R | Authors: | Lu, P, DiMaio, F, Min, D, Bowie, J, Wei, K.Y, Baker, D. | Deposit date: | 2017-10-05 | Release date: | 2018-03-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.889 Å) | Cite: | Accurate computational design of multipass transmembrane proteins. Science, 359, 2018
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6JH7
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![BU of 6jh7 by Molmil](/molmil-images/mine/6jh7) | Crystal structure of AerF from Microcystis aeruginosa | Descriptor: | ACETATE ION, DI(HYDROXYETHYL)ETHER, Short chain dehydrogenase family protein, ... | Authors: | Qiu, X. | Deposit date: | 2019-02-17 | Release date: | 2019-11-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Structural and functional investigation of AerF, a NADPH-dependent alkenal double bond reductase participating in the biosynthesis of Choi moiety of aeruginosin J.Struct.Biol., 2019
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6JHB
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![BU of 6jhb by Molmil](/molmil-images/mine/6jhb) | |
6MU2
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![BU of 6mu2 by Molmil](/molmil-images/mine/6mu2) | Structure of full-length IP3R1 channel in the Apo-state | Descriptor: | Inositol 1,4,5-trisphosphate receptor type 1 | Authors: | Serysheva, I.I, Fan, G, Baker, M.R, Wang, Z, Seryshev, A, Ludtke, S.J, Baker, M.L. | Deposit date: | 2018-10-22 | Release date: | 2018-12-05 | Last modified: | 2019-11-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM reveals ligand induced allostery underlying InsP3R channel gating. Cell Res., 28, 2018
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5MWE
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![BU of 5mwe by Molmil](/molmil-images/mine/5mwe) | Complex between the Leucine Zipper (LZ, residues 490-567) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) | Descriptor: | 1,2-ETHANEDIOL, 3,3',3''-phosphanetriyltripropanoic acid, Centrosomin, ... | Authors: | Feng, Z, Johnson, S, Raff, J.W, Lea, S.M. | Deposit date: | 2017-01-18 | Release date: | 2017-06-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Structural Basis for Mitotic Centrosome Assembly in Flies. Cell, 169, 2017
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2UXA
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![BU of 2uxa by Molmil](/molmil-images/mine/2uxa) | Crystal structure of the GluR2-flip ligand binding domain, r/g unedited. | Descriptor: | GLUTAMATE RECEPTOR SUBUNIT GLUR2-FLIP, GLUTAMIC ACID, ZINC ION | Authors: | Greger, I.H, Akamine, P, Khatri, L, Ziff, E.B. | Deposit date: | 2007-03-27 | Release date: | 2007-04-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Developmentally Regulated, Combinatorial RNA Processing Modulates Ampa Receptor Biogenesis. Neuron, 51, 2006
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5MW9
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![BU of 5mw9 by Molmil](/molmil-images/mine/5mw9) | Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) - L535E mutant form | Descriptor: | Centrosomin, ZINC ION | Authors: | Feng, Z, Johnson, S, Raff, J.W, Lea, S.M. | Deposit date: | 2017-01-18 | Release date: | 2017-06-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis for Mitotic Centrosome Assembly in Flies. Cell, 169, 2017
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