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4FXM
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BU of 4fxm by Molmil
Crystal structure of the complex of a human telomeric repeat G-quadruplex and N-methyl mesoporphyrin IX (P21212)
Descriptor: DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), N-METHYLMESOPORPHYRIN, POTASSIUM ION
Authors:Nicoludis, J.M, Miller, S.T, Jeffrey, P, Lawton, T.J, Rosenzweig, A.C, Yatsunyk, L.A.
Deposit date:2012-07-03
Release date:2012-12-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.651 Å)
Cite:Optimized End-Stacking Provides Specificity of N-Methyl Mesoporphyrin IX for Human Telomeric G-Quadruplex DNA.
J.Am.Chem.Soc., 134, 2012
6TZQ
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BU of 6tzq by Molmil
A DNA G-quadruplex/i-motif hybrid
Descriptor: BARIUM ION, DNA (5'-D(*CP*CP*AP*GP*GP*CP*TP*GP*CP*AP*A)-3')
Authors:Chu, B, Paukstelis, P.J.
Deposit date:2019-08-13
Release date:2019-10-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:A DNA G-quadruplex/i-motif hybrid.
Nucleic Acids Res., 47, 2019
6TZR
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A DNA G-quadruplex/i-motif hybrid
Descriptor: BARIUM ION, DNA (5'-D(*CP*CP*AP*GP*GP*CP*(BRU)P*GP*CP*AP*A)-3')
Authors:Chu, B, Paukstelis, P.J.
Deposit date:2019-08-13
Release date:2019-10-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A DNA G-quadruplex/i-motif hybrid.
Nucleic Acids Res., 47, 2019
6ZL9
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BU of 6zl9 by Molmil
Structure of a parallel c-Myc modified with 5' duplex stem-loop overhang
Descriptor: DNA (35-MER)
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2020-06-30
Release date:2020-10-07
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Quadruplex-Duplex Junction: A High-Affinity Binding Site for Indoloquinoline Ligands.
Chemistry, 26, 2020
6A85
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BU of 6a85 by Molmil
Crystal structure of a novel DNA quadruplex
Descriptor: AMMONIUM ION, DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*GP*GP*GP*TP*GP*CP*GP*TP*T)-3'), LEAD (II) ION, ...
Authors:Liu, H.H, Gan, J.H.
Deposit date:2018-07-06
Release date:2019-03-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:High-resolution DNA quadruplex structure containing all the A-, G-, C-, T-tetrads.
Nucleic Acids Res., 46, 2018
6ZTE
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BU of 6zte by Molmil
Structure of a parallel c-myc modified with 5' duplex stem-loop and 3' diagonal snap-back loop
Descriptor: DNA (36-MER)
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2020-07-20
Release date:2020-10-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Quadruplex-Duplex Junction: A High-Affinity Binding Site for Indoloquinoline Ligands.
Chemistry, 26, 2020
7N7E
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BU of 7n7e by Molmil
Solution structure of the MYC promoter G-quadruplex in complex with berberine: conformer B
Descriptor: BERBERINE, Myc2345
Authors:Dickerhoff, J, Yang, D.
Deposit date:2021-06-10
Release date:2021-11-03
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Berberine Molecular Recognition of the Parallel MYC G-Quadruplex in Solution.
J.Med.Chem., 64, 2021
6ZX7
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BU of 6zx7 by Molmil
Antiparallel basket-type G-quadruplex DNA structure formed in human Bcl-2 promoter
Descriptor: bcl2ex
Authors:Bielskute, S, Plavec, J, Podbevsek, P.
Deposit date:2020-07-29
Release date:2021-03-10
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Oxidative lesions modulate G-quadruplex stability and structure in the human BCL2 promoter.
Nucleic Acids Res., 49, 2021
6ZX6
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BU of 6zx6 by Molmil
Antiparallel basket-type G-quadruplex DNA structure formed in human Bcl-2 promoter containing 8-oxoG
Descriptor: bcl2ex-oxoG19
Authors:Bielskute, S, Plavec, J, Podbevsek, P.
Deposit date:2020-07-29
Release date:2021-03-10
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Oxidative lesions modulate G-quadruplex stability and structure in the human BCL2 promoter.
Nucleic Acids Res., 49, 2021
2AQY
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BU of 2aqy by Molmil
(3+1) assembly of three human telomeric DNA repeats into an asymmetrical dimeric G-quadruplex
Descriptor: 5'-D(*GP*(OIP)P*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*T)-3', 5'-D(*TP*AP*GP*GP*GP*(DU))-3'
Authors:Zhang, N, Phan, A.T, Patel, D.J.
Deposit date:2005-08-18
Release date:2006-03-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:(3 + 1) Assembly of three human telomeric repeats into an asymmetric dimeric G-quadruplex
J.Am.Chem.Soc., 127, 2005
6V0L
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BU of 6v0l by Molmil
PDGFR-b Promoter Forms a G-Vacancy Quadruplex that Can be Complemented by dGMP: Molecular Structure and Recognition of Guanine Derivatives and Metabolites
Descriptor: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, DNA (5'-D(*(3D1)P*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*AP*CP*A)-3')
Authors:Wang, K.B, Dickerhoff, J, Wu, G, Yang, D.
Deposit date:2019-11-18
Release date:2020-03-11
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:PDGFR-beta Promoter Forms a Vacancy G-Quadruplex that Can Be Filled in by dGMP: Solution Structure and Molecular Recognition of Guanine Metabolites and Drugs.
J.Am.Chem.Soc., 142, 2020
6GH0
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BU of 6gh0 by Molmil
Two-quartet kit* G-quadruplex is formed via double-stranded pre-folded structure
Descriptor: DNA (5'-D(*GP*GP*CP*GP*AP*GP*GP*AP*GP*GP*GP*GP*CP*GP*TP*GP*GP*CP*CP*GP*GP*C)-3')
Authors:Kotar, A, Rigo, R, Sissi, C, Plavec, J.
Deposit date:2018-05-04
Release date:2019-01-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Two-quartet kit* G-quadruplex is formed via double-stranded pre-folded structure.
Nucleic Acids Res., 47, 2019
1JVC
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BU of 1jvc by Molmil
Dimeric DNA Quadruplex Containing Major Groove-Aligned A.T.A.T and G.C.G.C Tetrads Stabilized by Inter-Subunit Watson-Crick A:T and G:C Pairs
Descriptor: 5'-D(*GP*AP*GP*CP*AP*GP*GP*T)-3'
Authors:Zhang, N, Gorin, A, Majumdar, A, Kettani, A, Chernichenko, N, Skripkin, E, Patel, D.J.
Deposit date:2001-08-29
Release date:2001-10-24
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Dimeric DNA quadruplex containing major groove-aligned A-T-A-T and G-C-G-C tetrads stabilized by inter-subunit Watson-Crick A-T and G-C pairs.
J.Mol.Biol., 312, 2001
8RW2
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BU of 8rw2 by Molmil
Structure of a chair-type antiparallel quadruplex-duplex hybrid at pH 6
Descriptor: DNA (33-MER)
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2024-02-02
Release date:2024-03-27
Last modified:2024-06-05
Method:SOLUTION NMR
Cite:A pH-Responsive Topological Switch Based on a DNA Quadruplex-Duplex Hybrid.
Chemistry, 30, 2024
8S1W
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BU of 8s1w by Molmil
Structure of a quadruplex-duplex hybrid with a (-pd+l) loop progression
Descriptor: DNA (33-MER)
Authors:Vianney, Y.M, Jana, J, Weisz, K.
Deposit date:2024-02-16
Release date:2024-03-27
Last modified:2024-06-05
Method:SOLUTION NMR
Cite:A pH-Responsive Topological Switch Based on a DNA Quadruplex-Duplex Hybrid.
Chemistry, 30, 2024
6KN4
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BU of 6kn4 by Molmil
HUMAN PARALLEL STRANDED 7-MER G-QUADRUPLEX COMPLEXED WITH 2 ADRIAMYCIN (DM2) MOLECULES
Descriptor: DNA (5'-D(*TP*TP*AP*GP*GP*GP*T)-3'), DOXORUBICIN
Authors:Barthwal, R, Raje, S, Pandav, K.
Deposit date:2019-08-03
Release date:2020-03-18
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for stabilization of human telomeric G-quadruplex [d-(TTAGGGT)] 4 by anticancer drug adriamycin.
J.Biomol.Struct.Dyn., 39, 2021
6KXZ
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BU of 6kxz by Molmil
HUMAN PARALLEL STRANDED 7-MER G-QUADRUPLEX COMPLEXED WITH 2 EPIRUBICIN (EPI) MOLECULES
Descriptor: 4'-EPIDOXORUBICIN, [TTAGGGT]4-EPI-Complex
Authors:Barthwal, R, Raje, S, Pandav, K.
Deposit date:2019-09-15
Release date:2020-09-16
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis for stabilization of human telomeric G-quadruplex [d-(TTAGGGT)] 4 by anticancer drug epirubicin.
Bioorg.Med.Chem., 28, 2020
1MYQ
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BU of 1myq by Molmil
An intramolecular quadruplex of (GGA)(4) triplet repeat DNA with a G:G:G:G tetrad and a G(:A):G(:A):G(:A):G heptad, and its dimeric interaction
Descriptor: 5'-D(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3'
Authors:Matsugami, A, Ouhashi, K, Kanagawa, M, Liu, H, Kanagawa, S, Uesugi, S, Katahira, M.
Deposit date:2002-10-04
Release date:2002-10-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:An intramolecular quadruplex of (GGA)(4) triplet repeat DNA with a G:G:G:G tetrad and a G(:A):G(:A):G(:A):G heptad, and its dimeric interaction.
J.Mol.Biol., 313, 2001
1FQP
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BU of 1fqp by Molmil
INTRAMOLECULAR QUADRUPLEX DNA WITH THREE GGGG REPEATS, NMR, PH 6.7, 0.1 M NA+ AND 4 MM (STRAND CONCENTRATION), 5 STRUCTURES
Descriptor: DNA (5'-D(GP*GP*GP*TP*TP*TP*TP*GP*GP*G)-3')
Authors:Keniry, M.A, Strahan, G.D, Owen, E.A, Shafer, R.H.
Deposit date:1996-08-01
Release date:1997-02-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the Na+ form of the dimeric guanine quadruplex [d(G3T4G3)]2.
Eur.J.Biochem., 233, 1995
2AVJ
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BU of 2avj by Molmil
G4(Br)UTTG4 dimeric quadruplex
Descriptor: 5'-D(*GP*GP*GP*GP*(BRU)P*TP*TP*GP*GP*GP*G)-3', CACODYLATE ION, POTASSIUM ION
Authors:Hazel, P, Parkinson, G.N, Neidle, S.
Deposit date:2005-08-30
Release date:2006-03-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Topology variation and loop structural homology in crystal and simulated structures of a bimolecular DNA quadruplex.
J.Am.Chem.Soc., 128, 2006
7N7D
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BU of 7n7d by Molmil
Solution structure of the MYC promoter G-quadruplex in complex with berberine: conformer A
Descriptor: BERBERINE, Myc2345
Authors:Dickerhoff, J, Yang, D.
Deposit date:2021-06-10
Release date:2021-11-03
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Berberine Molecular Recognition of the Parallel MYC G-Quadruplex in Solution.
J.Med.Chem., 64, 2021
7O1H
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BU of 7o1h by Molmil
Hybrid-2R quadruplex-duplex with (-p-p-l) topology and 3 syn residues
Descriptor: DNA (31-MER)
Authors:Mohr, S, Vianney, Y.M, Weisz, K.
Deposit date:2021-03-29
Release date:2021-05-19
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Expanding the Topological Landscape by a G-Column Flip of a Parallel G-Quadruplex.
Chemistry, 27, 2021
2AVH
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BU of 2avh by Molmil
G4T3G4 dimeric quadruplex structure
Descriptor: 5'-D(*GP*GP*GP*GP*TP*TP*TP*GP*GP*GP*G)-3', POTASSIUM ION
Authors:Hazel, P, Parkinson, G.N, Neidle, S.
Deposit date:2005-08-30
Release date:2006-03-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Topology variation and loop structural homology in crystal and simulated structures of a bimolecular DNA quadruplex.
J.Am.Chem.Soc., 128, 2006
2CHJ
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BU of 2chj by Molmil
NMR structure of TGLGLT quadruplex
Descriptor: 5'-D(*TP*G LCGP*G LCGP*TP)-3'
Authors:Nielsen, J.T, Petersen, M.
Deposit date:2006-03-15
Release date:2006-04-19
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR Solution Structures of Lna (Locked Nucleic Acid) Modified Quadruplexes
Nucleic Acids Res., 34, 2006
2CHK
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BU of 2chk by Molmil
NMR structure of TLLLLT quadruplex
Descriptor: 5'-D(*T LCG LCG LCG LCGP*TP)-3'
Authors:Nielsen, J.T, Petersen, M.
Deposit date:2006-03-15
Release date:2006-04-19
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR Solution Structures of Lna (Locked Nucleic Acid) Modified Quadruplexes
Nucleic Acids Res., 34, 2006

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