6V0L

PDGFR-b Promoter Forms a G-Vacancy Quadruplex that Can be Complemented by dGMP: Molecular Structure and Recognition of Guanine Derivatives and Metabolites

Summary for 6V0L

• Entry DOI: 10.2210/pdb6v0l/pdb
• NMR Information: BMRB: 30688
• Descriptor: DNA (5'-D(*(3D1)P*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*AP*CP*A)-3'), 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE (2 entities in total)
• Functional Keywords: g-quadruplex, pdgfr-b, promoter, dna
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 6277.13

Authors

Wang, K.B.,Dickerhoff, J.,Wu, G.,Yang, D. (deposition date: 2019-11-18, release date: 2020-03-11, Last modification date: 2020-04-01)

• Primary citation: Wang, K.B.,Dickerhoff, J.,Wu, G.,Yang, D.; PDGFR-beta Promoter Forms a Vacancy G-Quadruplex that Can Be Filled in by dGMP: Solution Structure and Molecular Recognition of Guanine Metabolites and Drugs.; J.Am.Chem.Soc., 142:5204-5211, 2020; PubMed: 32101424; DOI: 10.1021/jacs.9b12770

Experimental method

SOLUTION NMR