6KXZ

HUMAN PARALLEL STRANDED 7-MER G-QUADRUPLEX COMPLEXED WITH 2 EPIRUBICIN (EPI) MOLECULES

Summary for 6KXZ

• Entry DOI: 10.2210/pdb6kxz/pdb
• Descriptor: [TTAGGGT]4-EPI-Complex, 4'-EPIDOXORUBICIN (2 entities in total)
• Functional Keywords: g-quadruplex, epirubicin, epiadriamycin, dna
• Biological source: Homo sapiens
• Total number of polymer chains: 4
• Total formula weight: 9762.83

Authors

Barthwal, R.,Raje, S.,Pandav, K. (deposition date: 2019-09-15, release date: 2020-09-16, Last modification date: 2021-09-29)

• Primary citation: Barthwal, R.,Raje, S.,Pandav, K.; Structural basis for stabilization of human telomeric G-quadruplex [d-(TTAGGGT)] 4 by anticancer drug epirubicin.; Bioorg.Med.Chem., 28:115761-115761, 2020; PubMed: 32992248; DOI: 10.1016/j.bmc.2020.115761

Experimental method

SOLUTION NMR