7N7E

Solution structure of the MYC promoter G-quadruplex in complex with berberine: conformer B

Summary for 7N7E

• Entry DOI: 10.2210/pdb7n7e/pdb
• Related: 7N7D
• NMR Information: BMRB: 30924
• Descriptor: Myc2345, BERBERINE (2 entities in total)
• Functional Keywords: g-quadruplex dna, drug-dna complex, berberine, cancer, dna
• Biological source: Homo sapiens
• Total number of polymer chains: 1
• Total formula weight: 7706.24

Authors

Dickerhoff, J.,Yang, D. (deposition date: 2021-06-10, release date: 2021-11-03, Last modification date: 2024-05-15)

• Primary citation: Dickerhoff, J.,Brundridge, N.,McLuckey, S.A.,Yang, D.; Berberine Molecular Recognition of the Parallel MYC G-Quadruplex in Solution.; J.Med.Chem., 64:16205-16212, 2021; PubMed: 34677968; DOI: 10.1021/acs.jmedchem.1c01508

Experimental method

SOLUTION NMR