4FXM
Crystal structure of the complex of a human telomeric repeat G-quadruplex and N-methyl mesoporphyrin IX (P21212)
Summary for 4FXM
Entry DOI | 10.2210/pdb4fxm/pdb |
Descriptor | DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), POTASSIUM ION, N-METHYLMESOPORPHYRIN, ... (4 entities in total) |
Functional Keywords | parallel quadruplex, n-methyl mesoporphyrin ix, dna |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 7681.51 |
Authors | Nicoludis, J.M.,Miller, S.T.,Jeffrey, P.,Lawton, T.J.,Rosenzweig, A.C.,Yatsunyk, L.A. (deposition date: 2012-07-03, release date: 2012-12-26, Last modification date: 2023-09-13) |
Primary citation | Nicoludis, J.M.,Miller, S.T.,Jeffrey, P.D.,Barrett, S.P.,Rablen, P.R.,Lawton, T.J.,Yatsunyk, L.A. Optimized End-Stacking Provides Specificity of N-Methyl Mesoporphyrin IX for Human Telomeric G-Quadruplex DNA. J.Am.Chem.Soc., 134:20446-20456, 2012 Cited by PubMed: 23181361DOI: 10.1021/ja3088746 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.651 Å) |
Structure validation
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