6DVW
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![BU of 6dvw by Molmil](/molmil-images/mine/6dvw) | Cryo-EM structure of mouse TRPV3 | Descriptor: | Transient receptor potential cation channel subfamily V member 3 | Authors: | Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I. | Deposit date: | 2018-06-25 | Release date: | 2018-09-05 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structure and gating mechanism of the transient receptor potential channel TRPV3. Nat. Struct. Mol. Biol., 25, 2018
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6EMK
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![BU of 6emk by Molmil](/molmil-images/mine/6emk) | Cryo-EM Structure of Saccharomyces cerevisiae Target of Rapamycin Complex 2 | Descriptor: | Serine/threonine-protein kinase TOR2, Target of rapamycin complex 2 subunit AVO1, Target of rapamycin complex 2 subunit AVO2, ... | Authors: | Karuppasamy, M, Kusmider, B, Oliveira, T.M, Gaubitz, C, Prouteau, M, Loewith, R, Schaffitzel, C. | Deposit date: | 2017-10-02 | Release date: | 2017-12-06 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (7.9 Å) | Cite: | Cryo-EM structure of Saccharomyces cerevisiae target of rapamycin complex 2. Nat Commun, 8, 2017
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6UW6
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![BU of 6uw6 by Molmil](/molmil-images/mine/6uw6) | Cryo-EM structure of the human TRPV3 K169A mutant determined in lipid nanodisc | Descriptor: | Transient receptor potential cation channel subfamily V member 3, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | Authors: | Deng, Z, Yuan, P. | Deposit date: | 2019-11-04 | Release date: | 2020-07-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.66 Å) | Cite: | Gating of human TRPV3 in a lipid bilayer. Nat.Struct.Mol.Biol., 27, 2020
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6UW9
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![BU of 6uw9 by Molmil](/molmil-images/mine/6uw9) | |
6UW4
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![BU of 6uw4 by Molmil](/molmil-images/mine/6uw4) | Cryo-EM structure of human TRPV3 determined in lipid nanodisc | Descriptor: | SODIUM ION, Transient receptor potential cation channel subfamily V member 3, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | Authors: | Deng, Z, Yuan, P. | Deposit date: | 2019-11-04 | Release date: | 2020-07-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Gating of human TRPV3 in a lipid bilayer. Nat.Struct.Mol.Biol., 27, 2020
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6URQ
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![BU of 6urq by Molmil](/molmil-images/mine/6urq) | Complex structure of human poly-ADP-ribosyltransferase TNKS1 ARC2-ARC3 and P antigen family member 4 (PAGE4) | Descriptor: | GLYCEROL, P antigen family member 4, Poly [ADP-ribose] polymerase tankyrase-1, ... | Authors: | Zheng, Y, Koirala, S, Miller, D, Potts, P.R. | Deposit date: | 2019-10-24 | Release date: | 2020-07-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Tissue-Specific Regulation of the Wnt/ beta-Catenin Pathway by PAGE4 Inhibition of Tankyrase. Cell Rep, 32, 2020
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6V9Y
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![BU of 6v9y by Molmil](/molmil-images/mine/6v9y) | Structure of TRPA1 bound with A-967079, PMAL-C8 | Descriptor: | Transient receptor potential cation channel subfamily A member 1 | Authors: | Zhao, J, Lin King, J.V, Paulsen, C.E, Cheng, Y, Julius, D. | Deposit date: | 2019-12-16 | Release date: | 2020-05-06 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Irritant-evoked activation and calcium modulation of the TRPA1 receptor. Nature, 585, 2020
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6L93
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![BU of 6l93 by Molmil](/molmil-images/mine/6l93) | |
6UW8
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![BU of 6uw8 by Molmil](/molmil-images/mine/6uw8) | |
6V9X
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![BU of 6v9x by Molmil](/molmil-images/mine/6v9x) | Structure of TRPA1 modified by iodoacetamide, PMAL-C8 | Descriptor: | Transient receptor potential cation channel subfamily A member 1 | Authors: | Zhao, J, Lin King, J.V, Paulsen, C.E, Cheng, Y, Julius, D. | Deposit date: | 2019-12-16 | Release date: | 2020-05-06 | Last modified: | 2020-09-16 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Irritant-evoked activation and calcium modulation of the TRPA1 receptor. Nature, 585, 2020
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3V2O
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![BU of 3v2o by Molmil](/molmil-images/mine/3v2o) | Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2 | Descriptor: | Ankyrin repeat family A protein 2, Low-density lipoprotein receptor-related protein 2 | Authors: | Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2011-12-12 | Release date: | 2012-04-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock. Sci.Signal., 5, 2012
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3V31
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![BU of 3v31 by Molmil](/molmil-images/mine/3v31) | Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2 | Descriptor: | Ankyrin repeat family A protein 2, CHLORIDE ION, Histone deacetylase 4, ... | Authors: | Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2011-12-12 | Release date: | 2012-04-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock. Sci.Signal., 5, 2012
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3V79
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![BU of 3v79 by Molmil](/molmil-images/mine/3v79) | Structure of human Notch1 transcription complex including CSL, RAM, ANK, and MAML-1 on HES-1 promoter DNA sequence | Descriptor: | DNA 5'-D(*GP*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*AP*AP*A)-3', DNA 5'-D(*TP*TP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*TP*AP*AP*C)-3', Mastermind-like protein 1, ... | Authors: | Nam, Y, Sliz, P, Blacklow, S. | Deposit date: | 2011-12-20 | Release date: | 2012-02-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.85 Å) | Cite: | Conformational Locking upon Cooperative Assembly of Notch Transcription Complexes. Structure, 20, 2012
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6V9V
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![BU of 6v9v by Molmil](/molmil-images/mine/6v9v) | Structure of TRPA1 modified by Bodipy-iodoacetamide with bound calcium, LMNG | Descriptor: | CALCIUM ION, Transient receptor potential cation channel subfamily A member 1, ~{N}-[[2,2-bis(fluoranyl)-10,12-dimethyl-1,3-diaza-2$l^{4}-boratricyclo[7.3.0.0^{3,7}]dodeca-4,6,9,11-tetraen-4-yl]methyl]ethanamide | Authors: | Zhao, J, Lin King, J.V, Paulsen, C.E, Cheng, Y, Julius, D. | Deposit date: | 2019-12-16 | Release date: | 2020-05-06 | Last modified: | 2020-09-16 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Irritant-evoked activation and calcium modulation of the TRPA1 receptor. Nature, 585, 2020
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6LGP
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![BU of 6lgp by Molmil](/molmil-images/mine/6lgp) | cryo-EM structure of TRPV3 in lipid nanodisc | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, DIUNDECYL PHOSPHATIDYL CHOLINE, Transient receptor potential cation channel subfamily V member 3 | Authors: | Shimada, H, Kusakizako, T, Nishizawa, T, Nureki, O. | Deposit date: | 2019-12-05 | Release date: | 2020-06-24 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | The structure of lipid nanodisc-reconstituted TRPV3 reveals the gating mechanism. Nat.Struct.Mol.Biol., 27, 2020
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6V9W
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![BU of 6v9w by Molmil](/molmil-images/mine/6v9w) | Structure of TRPA1 (ligand-free) with bound calcium, LMNG | Descriptor: | CALCIUM ION, Transient receptor potential cation channel subfamily A member 1 | Authors: | Zhao, J, Lin King, J.V, Paulsen, C.E, Cheng, Y, Julius, D. | Deposit date: | 2019-12-16 | Release date: | 2020-05-06 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Irritant-evoked activation and calcium modulation of the TRPA1 receptor. Nature, 585, 2020
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3SO8
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![BU of 3so8 by Molmil](/molmil-images/mine/3so8) | Crystal Structure of ANKRA | Descriptor: | Ankyrin repeat family A protein 2 | Authors: | Xu, C, Bochkarev, A, Bian, C.B, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2011-06-30 | Release date: | 2011-10-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock. Sci.Signal., 5, 2012
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6MHS
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![BU of 6mhs by Molmil](/molmil-images/mine/6mhs) | Structure of the human TRPV3 channel in a putative sensitized conformation | Descriptor: | Transient receptor potential cation channel subfamily V member 3 | Authors: | Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y. | Deposit date: | 2018-09-18 | Release date: | 2018-10-03 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Conformational ensemble of the human TRPV3 ion channel. Nat Commun, 9, 2018
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6DMU
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![BU of 6dmu by Molmil](/molmil-images/mine/6dmu) | PI(4,5)P2 bound full-length rbTRPV5 | Descriptor: | Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | Authors: | Hughes, T.E.T, Pumroy, R.A, Moiseenkova-Bell, V.Y. | Deposit date: | 2018-06-05 | Release date: | 2018-10-24 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural insights on TRPV5 gating by endogenous modulators. Nat Commun, 9, 2018
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6MHX
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![BU of 6mhx by Molmil](/molmil-images/mine/6mhx) | Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (2) | Descriptor: | Transient receptor potential cation channel subfamily V member 3 | Authors: | Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y. | Deposit date: | 2018-09-18 | Release date: | 2018-10-03 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Conformational ensemble of the human TRPV3 ion channel. Nat Commun, 9, 2018
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3V2X
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![BU of 3v2x by Molmil](/molmil-images/mine/3v2x) | Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2 | Descriptor: | Ankyrin repeat family A protein 2, Low-density lipoprotein receptor-related protein 2 | Authors: | Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2011-12-12 | Release date: | 2012-04-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock. Sci.Signal., 5, 2012
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6MHW
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![BU of 6mhw by Molmil](/molmil-images/mine/6mhw) | Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (1) | Descriptor: | Transient receptor potential cation channel subfamily V member 3 | Authors: | Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y. | Deposit date: | 2018-09-18 | Release date: | 2018-10-03 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Conformational ensemble of the human TRPV3 ion channel. Nat Commun, 9, 2018
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6E2F
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![BU of 6e2f by Molmil](/molmil-images/mine/6e2f) | |
6MHV
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![BU of 6mhv by Molmil](/molmil-images/mine/6mhv) | Structure of human TRPV3 in the presence of 2-APB in C4 symmetry | Descriptor: | Transient receptor potential cation channel subfamily V member 3 | Authors: | Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y. | Deposit date: | 2018-09-18 | Release date: | 2018-10-03 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Conformational ensemble of the human TRPV3 ion channel. Nat Commun, 9, 2018
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6MHO
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![BU of 6mho by Molmil](/molmil-images/mine/6mho) | Structure of the human TRPV3 channel in the apo conformation | Descriptor: | Transient receptor potential cation channel subfamily V member 3 | Authors: | Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y. | Deposit date: | 2018-09-18 | Release date: | 2018-10-03 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Conformational ensemble of the human TRPV3 ion channel. Nat Commun, 9, 2018
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