Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2

Summary for 3V31

Related3SO8 3V2O 3V2X
DescriptorAnkyrin repeat family A protein 2, Histone deacetylase 4, CHLORIDE ION, ... (5 entities in total)
Functional Keywordsstructural genomics consortium, sgc, ankra2, ank repeat, protein binding, hdac4
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cytoskeleton  Q9H9E1
Nucleus P56524
Total number of polymer chains2
Total molecular weight20075.14
Lam, R.,Xu, C.,Bian, C.B.,Kania, J.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2011-12-12, release date: 2012-04-04, Last modification date: 2017-11-08)
Primary citation
Xu, C.,Jin, J.,Bian, C.,Lam, R.,Tian, R.,Weist, R.,You, L.,Nie, J.,Bochkarev, A.,Tempel, W.,Tan, C.S.,Wasney, G.A.,Vedadi, M.,Gish, G.D.,Arrowsmith, C.H.,Pawson, T.,Yang, X.J.,Min, J.
Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5:ra39-ra39, 2012
PubMed: 22649097 (PDB entries with the same primary citation)
DOI: 10.1126/scisignal.2002979
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.207200 7.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-12-02