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7UPS
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BU of 7ups by Molmil
Structural study of Legionella pneumophila effector DotY (Lpg0294)
Descriptor: 1,2-ETHANEDIOL, DotY (Lpg0294)
Authors:Chung, I.Y.W, Cygler, M.
Deposit date:2022-04-16
Release date:2022-08-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structural study of Legionella pneumophila effector DotY (Lpg0294), a component of the Dot/Icm type IV secretion system.
Acta Crystallogr.,Sect.F, 78, 2022
7UBX
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BU of 7ubx by Molmil
Structure of a pore forming fragment of Clostridium difficile toxin A in complex with VHH AA6
Descriptor: Nanobody VHH AA6, Toxin A
Authors:Chen, B, Rongsheng, J, Kay, P.
Deposit date:2022-03-15
Release date:2022-11-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Neutralizing epitopes on Clostridioides difficile toxin A revealed by the structures of two camelid VHH antibodies.
Front Immunol, 13, 2022
7UBY
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BU of 7uby by Molmil
Structure of the GTD domain of Clostridium difficile toxin A in complex with VHH AH3
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Glucosyltransferase TcdA, ...
Authors:Chen, B, Rongsheng, J, Kay, P.
Deposit date:2022-03-15
Release date:2022-11-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Neutralizing epitopes on Clostridioides difficile toxin A revealed by the structures of two camelid VHH antibodies.
Front Immunol, 13, 2022
3ZIR
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BU of 3zir by Molmil
minor-site specific NLS (B141)
Descriptor: B141NLS, IMPORTIN SUBUNIT ALPHA-2
Authors:Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B.
Deposit date:2013-01-10
Release date:2013-08-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha
Traffic, 14, 2013
7UFJ
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BU of 7ufj by Molmil
Structure of human MR1-ethylvanillin in complex with human MAIT A-F7 TCR
Descriptor: 3-ethoxy-4-hydroxybenzaldehyde, ACETATE ION, Beta-2-microglobulin, ...
Authors:Wang, C.J, Rossjohn, J, Le Nours, J.
Deposit date:2022-03-22
Release date:2022-12-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Quantitative affinity measurement of small molecule ligand binding to Major Histocompatibility Complex class-I related protein 1 MR1.
J.Biol.Chem., 298, 2022
7UYG
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BU of 7uyg by Molmil
Structure of the first OTU domain from Legionella pneumophila effector protein LotA
Descriptor: GLYCEROL, IODIDE ION, LotA
Authors:Pruneda, J.N.
Deposit date:2022-05-06
Release date:2022-12-21
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Mechanism of Lys6 poly-ubiquitin specificity by the L. pneumophila deubiquitinase LotA.
Mol.Cell, 83, 2023
7UYH
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BU of 7uyh by Molmil
Structure of the first OTU domain from Legionella pneumophila effector protein LotA bound to K6-linked diUb
Descriptor: LotA, Ubiquitin
Authors:Warren, G.D, Pruneda, J.N.
Deposit date:2022-05-06
Release date:2022-12-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of Lys6 poly-ubiquitin specificity by the L. pneumophila deubiquitinase LotA.
Mol.Cell, 83, 2023
7UXA
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BU of 7uxa by Molmil
Human tRNA Splicing Endonuclease Complex bound to pre-tRNA-ARG
Descriptor: MAGNESIUM ION, RNA (78-MER), tRNA-splicing endonuclease subunit Sen15, ...
Authors:Stanley, R.E, Hayne, C.K.
Deposit date:2022-05-05
Release date:2023-02-08
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex.
Nat.Struct.Mol.Biol., 30, 2023
7U21
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BU of 7u21 by Molmil
Human Class I MHC HLA-A2 in complex with AVGSYVYSV peptide
Descriptor: Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ...
Authors:Weiss, L.I, Baker, B.M.
Deposit date:2022-02-22
Release date:2022-06-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Physicochemical Heuristics for Identifying High Fidelity, Near-Native Structural Models of Peptide/MHC Complexes.
Front Immunol, 13, 2022
3P8M
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BU of 3p8m by Molmil
Human dynein light chain (DYNLL2) in complex with an in vitro evolved peptide dimerized by leucine zipper
Descriptor: Dynein light chain 2, General control protein GCN4
Authors:Rapali, P, Radnai, L, Suveges, D, Hetenyi, C, Harmat, V, Tolgyesi, F, Wahlgren, W.Y, Katona, G, Nyitray, L, Pal, G.
Deposit date:2010-10-14
Release date:2011-08-31
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Directed evolution reveals the binding motif preference of the LC8/DYNLL hub protein and predicts large numbers of novel binders in the human proteome.
Plos One, 6, 2011
7TYV
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BU of 7tyv by Molmil
Structure of Lassa Virus glycoprotein (Josiah) bound to Fab 25.10C
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 25.10C Fab Heavy Chain, ...
Authors:Enriquez, A.S, Hastie, K.M.
Deposit date:2022-02-14
Release date:2022-06-01
Last modified:2022-06-15
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Delineating the mechanism of anti-Lassa virus GPC-A neutralizing antibodies.
Cell Rep, 39, 2022
6Z6K
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BU of 6z6k by Molmil
Cryo-EM structure of yeast reconstituted Lso2 bound to 80S ribosomes
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R.
Deposit date:2020-05-28
Release date:2020-07-29
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
7TVH
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BU of 7tvh by Molmil
Hyperlytic variant of Tae1, Type VI secretion amidase effector 1, from Pseudomonas aeruginosa (Cys110Ser)
Descriptor: Peptidoglycan amidase Tse1
Authors:Radkov, A, Saunders, H, Chou, S.
Deposit date:2022-02-04
Release date:2022-07-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Antibacterial potency of type VI amidase effector toxins is dependent on substrate topology and cellular context.
Elife, 11, 2022
3J2A
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BU of 3j2a by Molmil
Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM
Descriptor: 16S rRNA
Authors:Guo, Q, Goto, S, Chen, Y, Muto, A, Himeno, H, Deng, H, Lei, J, Gao, N.
Deposit date:2012-09-28
Release date:2013-01-16
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (13.1 Å)
Cite:Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
6G04
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BU of 6g04 by Molmil
NMR Solution Structure of Yeast TSR2(1-152) in Complex with S26A(100-119)
Descriptor: 40S ribosomal protein S26-A, Pre-rRNA-processing protein TSR2
Authors:Michel, E, Schuetz, S, Damberger, F.F, Allain, F.H.-T, Panse, V.G.
Deposit date:2018-03-16
Release date:2018-09-19
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2.
Nat Commun, 9, 2018
8UKH
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BU of 8ukh by Molmil
Crystal structure of Plasmodium falciparum CelTOS in complex with antibody 4h12
Descriptor: 4h12 heavy chain, 4h12 light chain, Cell traversal protein for ookinetes and sporozoites
Authors:Tang, W.K, Tolia, N.H, Urusova, D.
Deposit date:2023-10-13
Release date:2024-09-11
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:Multistage protective anti-CelTOS monoclonal antibodies with cross-species sterile protection against malaria.
Nat Commun, 15, 2024
8ULF
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BU of 8ulf by Molmil
Crystal structure of Plasmodium vivax CelTOS in complex with antibody 7g7
Descriptor: 7g7 heavy chain, 7g7 light chain, Pv cell-traversal protein, ...
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2023-10-16
Release date:2024-09-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Multistage protective anti-CelTOS monoclonal antibodies with cross-species sterile protection against malaria.
Nat Commun, 15, 2024
7V6W
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BU of 7v6w by Molmil
Crystal structure of heterohexameric Sa2YoeB-Sa2YefM complex bound to 26bp-DNA
Descriptor: Antitoxin, DNA (25-MER), DNA (26-MER), ...
Authors:Xue, L, Khan, M.H, Yue, J.
Deposit date:2021-08-20
Release date:2021-12-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The two paralogous copies of the YoeB-YefM toxin-antitoxin module in Staphylococcus aureus differ in DNA binding and recognition patterns.
J.Biol.Chem., 298, 2022
7VWS
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BU of 7vws by Molmil
Carbazole Prenyl Transferase LvqB4
Descriptor: 2-methyl-1-[(2R)-2-oxidanylpropyl]-9H-carbazole-3,4-dione, LvqB4, MAGNESIUM ION, ...
Authors:Suemune, H, Nagata, R, Kuzuyama, T, Nagano, S.
Deposit date:2021-11-11
Release date:2022-03-23
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Structural Basis for the Prenylation Reaction of Carbazole-Containing Natural Products Catalyzed by Squalene Synthase-Like Enzymes.
Angew.Chem.Int.Ed.Engl., 61, 2022
7VWT
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BU of 7vwt by Molmil
Carbazole Prenyl Transferase CqsB4
Descriptor: 2-methyl-1-[(2R)-2-oxidanylpropyl]-9H-carbazole-3,4-dione, CqsB4, DI(HYDROXYETHYL)ETHER, ...
Authors:Suemune, H, Nagata, R, Kuzuyama, T, Nagano, S.
Deposit date:2021-11-11
Release date:2022-03-23
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structural Basis for the Prenylation Reaction of Carbazole-Containing Natural Products Catalyzed by Squalene Synthase-Like Enzymes.
Angew.Chem.Int.Ed.Engl., 61, 2022
4R3Z
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BU of 4r3z by Molmil
Crystal structure of human ArgRS-GlnRS-AIMP1 complex
Descriptor: Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Arginine--tRNA ligase, cytoplasmic, ...
Authors:Fu, Y, Kim, Y, Cho, Y.
Deposit date:2014-08-18
Release date:2014-10-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (4.033 Å)
Cite:Structure of the ArgRS-GlnRS-AIMP1 complex and its implications for mammalian translation
Proc.Natl.Acad.Sci.USA, 111, 2014
6G03
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BU of 6g03 by Molmil
NMR Solution Structure of yeast TSR2(1-152)
Descriptor: Pre-rRNA-processing protein TSR2
Authors:Michel, E, Schuetz, S, Damberger, F.F, Allain, F.H.-T, Panse, V.G.
Deposit date:2018-03-16
Release date:2018-09-19
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2.
Nat Commun, 9, 2018
3KMA
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BU of 3kma by Molmil
Crystal Structure of vSET under Condition A
Descriptor: A612L protein, CHLORIDE ION, GLYCEROL, ...
Authors:Wei, H, Zhou, M.M.
Deposit date:2009-11-10
Release date:2010-11-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Dimerization of a viral SET protein endows its function.
Proc.Natl.Acad.Sci.USA, 107, 2010
3ZIQ
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BU of 3ziq by Molmil
minor-site specific NLS (B6)
Descriptor: B6NLS, IMPORTIN SUBUNIT ALPHA-2
Authors:Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B.
Deposit date:2013-01-10
Release date:2013-08-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha
Traffic, 14, 2013
1C4O
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BU of 1c4o by Molmil
CRYSTAL STRUCTURE OF THE DNA NUCLEOTIDE EXCISION REPAIR ENZYME UVRB FROM THERMUS THERMOPHILUS
Descriptor: DNA NUCLEOTIDE EXCISION REPAIR ENZYME UVRB, SULFATE ION, octyl beta-D-glucopyranoside
Authors:Machius, M, Henry, L, Palnitkar, M, Deisenhofer, J.
Deposit date:1999-09-14
Release date:2000-07-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the DNA nucleotide excision repair enzyme UvrB from Thermus thermophilus.
Proc.Natl.Acad.Sci.USA, 96, 1999

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