8UKH

Crystal structure of Plasmodium falciparum CelTOS in complex with antibody 4h12

Summary for 8UKH

• Entry DOI: 10.2210/pdb8ukh/pdb
• Descriptor: Cell traversal protein for ookinetes and sporozoites, 4h12 heavy chain, 4h12 light chain, ... (4 entities in total)
• Functional Keywords: transmission-blocking, membrane disruption, cell invasion
• Biological source: Plasmodium falciparum 3D7; More
• Total number of polymer chains: 12
• Total formula weight: 259712.27

Authors

Tang, W.K.,Tolia, N.H.,Urusova, D. (deposition date: 2023-10-13, release date: 2024-09-11)

• Primary citation: Tang, W.K.,Salinas, N.D.,Kolli, S.K.,Xu, S.,Urusova, D.V.,Kumar, H.,Jimah, J.R.,Subramani, P.A.,Ogbondah, M.M.,Barnes, S.J.,Adams, J.H.,Tolia, N.H.; Multistage protective anti-CelTOS monoclonal antibodies with cross-species sterile protection against malaria.; Nat Commun, 15:7487-7487, 2024; PubMed: 39209843; DOI: 10.1038/s41467-024-51701-2

Experimental method

X-RAY DIFFRACTION (3.52 Å)