7UXA

Human tRNA Splicing Endonuclease Complex bound to pre-tRNA-ARG

Summary for 7UXA

• Entry DOI: 10.2210/pdb7uxa/pdb
• EMDB information: 26856
• Descriptor: tRNA-splicing endonuclease subunit Sen34, tRNA-splicing endonuclease subunit Sen15, tRNA-splicing endonuclease subunit Sen2, ... (6 entities in total)
• Functional Keywords: splicing endonuclease, pre-trna, tsen, enda, splicing-rna complex, splicing/rna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 203643.78

Authors

Stanley, R.E.,Hayne, C.K. (deposition date: 2022-05-05, release date: 2023-02-08, Last modification date: 2023-07-05)

• Primary citation: Hayne, C.K.,Butay, K.J.U.,Stewart, Z.D.,Krahn, J.M.,Perera, L.,Williams, J.G.,Petrovitch, R.M.,Deterding, L.J.,Matera, A.G.,Borgnia, M.J.,Stanley, R.E.; Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex.; Nat.Struct.Mol.Biol., 30:824-833, 2023; PubMed: 37231153; DOI: 10.1038/s41594-023-00991-z

Experimental method

ELECTRON MICROSCOPY (3.28 Å)