7UXA

Human tRNA Splicing Endonuclease Complex bound to pre-tRNA-ARG

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000213	molecular_function	tRNA-intron endonuclease activity
A	0000214	cellular_component	tRNA-intron endonuclease complex
A	0000379	biological_process	tRNA-type intron splice site recognition and cleavage
A	0003676	molecular_function	nucleic acid binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005730	cellular_component	nucleolus
A	0006388	biological_process	tRNA splicing, via endonucleolytic cleavage and ligation
A	0006397	biological_process	mRNA processing
A	0008033	biological_process	tRNA processing
A	0016829	molecular_function	lyase activity
B	0003676	molecular_function	nucleic acid binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005730	cellular_component	nucleolus
B	0006388	biological_process	tRNA splicing, via endonucleolytic cleavage and ligation
B	0006397	biological_process	mRNA processing
B	0008033	biological_process	tRNA processing
C	0000213	molecular_function	tRNA-intron endonuclease activity
C	0000214	cellular_component	tRNA-intron endonuclease complex
C	0000379	biological_process	tRNA-type intron splice site recognition and cleavage
C	0003676	molecular_function	nucleic acid binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005730	cellular_component	nucleolus
C	0005813	cellular_component	centrosome
C	0005829	cellular_component	cytosol
C	0006388	biological_process	tRNA splicing, via endonucleolytic cleavage and ligation
C	0006397	biological_process	mRNA processing
C	0008033	biological_process	tRNA processing
C	0016829	molecular_function	lyase activity
D	0000214	cellular_component	tRNA-intron endonuclease complex
D	0000379	biological_process	tRNA-type intron splice site recognition and cleavage
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005730	cellular_component	nucleolus
D	0006388	biological_process	tRNA splicing, via endonucleolytic cleavage and ligation
D	0006397	biological_process	mRNA processing
D	0008033	biological_process	tRNA processing

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: N-acetylmethionine => ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22814378

Chain	Residue	Details
D	MET1
C	ALA377
C	ALA416

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231

Chain	Residue	Details
D	SER178
C	SER411
C	SER415

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
D	TYR180

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
D	SER267

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site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Omega-N-methylarginine => ECO:0007744|PubMed:24129315

Chain	Residue	Details
D	ARG316

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