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4ZVQ
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BU of 4zvq by Molmil
Caspase-7 Variant 2 (V2) with reprogrammed substrate specificity due to Y230V/W232M/Q276C substitutions bound to VEID inhibitor.
Descriptor: Caspase-7, Peptide ACE-VAL-GLU-ILE-ASA
Authors:Hill, M.E, MacPherson, D.J, Hardy, J.A.
Deposit date:2015-05-18
Release date:2016-04-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition.
Acs Chem.Biol., 11, 2016
5A95
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BU of 5a95 by Molmil
Crystal structure of beta-glucanase SdGluc5_26A from Saccharophagus degradans in complex with tetrasaccharide A, form 2
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Sulzenbacher, G, Lafond, M, Freyd, T, Henrissat, B, Coutinho, R.M, Berrin, J.G, Garron, M.L.
Deposit date:2015-07-17
Release date:2016-01-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The Quaternary Structure of a Glycoside Hydrolase Dictates Specificity Towards Beta-Glucans
J.Biol.Chem., 291, 2016
5A8N
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Crystal structure of the native form of beta-glucanase SdGluc5_26A from Saccharophagus degradans
Descriptor: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
Authors:Sulzenbacher, G, Lafond, M, Freyd, T, Henrissat, B, Coutinho, R.M, Berrin, J.G, Garron, M.L.
Deposit date:2015-07-16
Release date:2016-01-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The Quaternary Structure of a Glycoside Hydrolase Dictates Specificity Towards Beta-Glucans
J.Biol.Chem., 291, 2016
5A2K
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BU of 5a2k by Molmil
Crystal structure of scFv-SM3 in complex with APD-TGalNAc-RP
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, ANTIGEN TN, ...
Authors:Martinez-Saez, N, Castro-Lopez, J, Valero-Gonzalez, J, Madariaga, D, Companon, I, Somovilla, V.J, Salvado, M, Asensio, J.L, Jimenez-Barbero, J, Avenoza, A, Busto, J.H, Bernardes, G.J.L, Peregrina, J.M, Hurtado-Guerrero, R, Corzana, F.
Deposit date:2015-05-20
Release date:2015-06-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an Anti-Muc1 Antibody.
Angew.Chem.Int.Ed.Engl., 54, 2015
5FML
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BU of 5fml by Molmil
Crystal structure of the endonuclease from the PA subunit of influenza B virus bound to the PB2 subunit NLS peptide
Descriptor: GLYCEROL, MAGNESIUM ION, PA SUBUNIT OF INFLUENZA B POLYMERASE, ...
Authors:Guilligay, D, Gaudon, S, Cusack, S.
Deposit date:2015-11-06
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of Pb2 Domains.
Mol.Cell, 61, 2016
8GU3
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BU of 8gu3 by Molmil
Crystal structure of Caenorhabditis elegans METT-10 methyltransferase domain
Descriptor: U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase
Authors:Ju, J, Tomita, K.
Deposit date:2022-09-09
Release date:2023-02-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structure of the Caenorhabditis elegans m6A methyltransferase METT10 that regulates SAM homeostasis.
Nucleic Acids Res., 51, 2023
4CE4
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39S large subunit of the porcine mitochondrial ribosome
Descriptor: 16S Ribosomal RNA, ICT1, MRPL13, ...
Authors:Greber, B.J, Boehringer, D, Leitner, A, Bieri, P, Voigts-Hoffmann, F, Erzberger, J.P, Leibundgut, M, Aebersold, R, Ban, N.
Deposit date:2013-11-08
Release date:2013-12-18
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Architecture of the Large Subunit of the Mammalian Mitochondrial Ribosome.
Nature, 505, 2014
5YZ1
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BU of 5yz1 by Molmil
Crystal structure of human Archease
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Protein archease
Authors:Duan, S.Y, Li, J.X.
Deposit date:2017-12-11
Release date:2019-01-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Crystal structure of human archease, a key cofactor of tRNA splicing ligase complex.
Int.J.Biochem.Cell Biol., 122, 2020
3CC4
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BU of 3cc4 by Molmil
Co-crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
Authors:Blaha, G, Gurel, G.
Deposit date:2008-02-24
Release date:2008-05-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
J.Mol.Biol., 379, 2008
1T4N
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BU of 1t4n by Molmil
Solution structure of Rnt1p dsRBD
Descriptor: Ribonuclease III
Authors:Leulliot, N, Quevillon-Cheruel, S, Graille, M, van Tilbeurgh, H, Leeper, T.C, Godin, K.S, Edwards, T.E, Sigurdsson, S.T, Rozenkrants, N, Nagel, R.J, Ares, M, Varani, G.
Deposit date:2004-04-30
Release date:2004-07-13
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A new alpha-helical extension promotes RNA binding by the dsRBD of Rnt1p RNAse III
Embo J., 23, 2004
1T4O
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BU of 1t4o by Molmil
Crystal structure of rnt1p dsRBD
Descriptor: Ribonuclease III
Authors:Leulliot, N, Quevillon-Cheruel, S, Graille, M, van Tilbeurgh, H, Leeper, T.C, Godin, K.S, Edwards, T.E, Sigurdsson, S.T, Rozenkrants, N, Nagel, R.J, Ares Jr, M, Varani, G.
Deposit date:2004-04-30
Release date:2004-06-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A new alpha-helical extension promotes RNA binding by the dsRBD of Rnt1p RNAse III
Embo J., 23, 2004
6P19
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BU of 6p19 by Molmil
Q21 transcription antitermination complex: loaded complex
Descriptor: DNA (123-MER) fragment carrying phage-21 pR' promoter, pause element, and transcribed region, ...
Authors:Yin, Z, Ebright, R.H.
Deposit date:2019-05-19
Release date:2019-06-26
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of Q-dependent antitermination.
Proc.Natl.Acad.Sci.USA, 116, 2019
6P18
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BU of 6p18 by Molmil
Q21 transcription antitermination complex: loading complex
Descriptor: DNA (67-MER) fragment carrying phage-21 pR' promoter and pause element, nontemplate strand, template strand, ...
Authors:Yin, Z, Ebright, R.H.
Deposit date:2019-05-19
Release date:2019-06-26
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of Q-dependent antitermination.
Proc.Natl.Acad.Sci.USA, 116, 2019
6XLL
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BU of 6xll by Molmil
Cryo-EM structure of E. coli RNAP-promoter initial transcribing complex with 5-nt RNA transcript (RPitc-5nt)
Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Yang, Y, Liu, C, Liu, B.
Deposit date:2020-06-28
Release date:2021-04-07
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
3RTX
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BU of 3rtx by Molmil
Crystal structure of mammalian capping enzyme (Mce1) and Pol II CTD complex
Descriptor: GUANINE, RNA Polymerase II C-terminal domain, mRNA-capping enzyme
Authors:Ghosh, A, Lima, C.D.
Deposit date:2011-05-04
Release date:2011-06-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural insights to how mammalian capping enzyme reads the CTD code.
Mol.Cell, 43, 2011
7QUU
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BU of 7quu by Molmil
Red1-Iss10 complex
Descriptor: NURS complex subunit red1, Uncharacterized protein C7D4.14c
Authors:Mackereth, C.D, Kadlec, J, Laroussi, H.
Deposit date:2022-01-18
Release date:2022-09-07
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural analysis of Red1 as a conserved scaffold of the RNA-targeting MTREC/PAXT complex.
Nat Commun, 13, 2022
3RER
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BU of 3rer by Molmil
Crystal structure of E. coli Hfq in complex with AU6A RNA and ADP
Descriptor: 5'-R(*AP*UP*UP*UP*UP*UP*UP*A)-3', ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Wang, W.W, Wu, J.H, Shi, Y.Y.
Deposit date:2011-04-05
Release date:2011-10-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Cooperation of Escherichia coli Hfq hexamers in DsrA binding.
Genes Dev., 25, 2011
8IGS
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BU of 8igs by Molmil
Cryo-EM structure of RNAP-promoter open complex at lambda promoter PRE
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zhao, M, Gao, B, Wen, A, Feng, Y, Lu, Y.
Deposit date:2023-02-21
Release date:2023-05-17
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of lambda CII-dependent transcription activation.
Structure, 31, 2023
4D5Y
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BU of 4d5y by Molmil
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
Descriptor: 28S Ribosomal RNA, 5.8S Ribosomal RNA, 5S Ribosomal RNA, ...
Authors:Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T.
Deposit date:2014-11-07
Release date:2015-03-04
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Cryo-Em Structures of Ribosomal 80S Complexes with Termination Factors and Cricket Paralysis Virus Ires Reveal the Ires in the Translocated State
Mol.Cell, 57, 2015
8UO6
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BU of 8uo6 by Molmil
HIV-1 Rev Response Element (RRE) Stem-Loop II (SLII)
Descriptor: HIV-1 Rev Response Element Stem-Loop II with tRNA scaffold
Authors:Tipo, J, Gottipati, K, Choi, K.
Deposit date:2023-10-19
Release date:2024-06-05
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of HIV-1 RRE stem-loop II identifies two conformational states of the high-affinity Rev binding site.
Nat Commun, 15, 2024
6D1R
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BU of 6d1r by Molmil
Structure of Staphylococcus aureus RNase P protein at 2.0 angstrom
Descriptor: Ribonuclease P protein component
Authors:Ha, L, Colquhoun, J, Noinaj, N, Das, C, Dunman, P, Flaherty, D.P.
Deposit date:2018-04-12
Release date:2018-09-26
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.995 Å)
Cite:Crystal structure of the ribonuclease-P-protein subunit from Staphylococcus aureus.
Acta Crystallogr F Struct Biol Commun, 74, 2018
7MNX
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BU of 7mnx by Molmil
Crystal Structure of Nup358/RanBP2 Ran-binding domain 2 in complex with Ran-GPPNHP
Descriptor: E3 SUMO-protein ligase RanBP2, GTP-binding nuclear protein Ran, MAGNESIUM ION, ...
Authors:Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
Deposit date:2021-05-01
Release date:2022-06-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
7MO5
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BU of 7mo5 by Molmil
Crystal Structure of the ZnF4 of Nucleoporin NUP153 in complex with Ran-GDP
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
Deposit date:2021-05-01
Release date:2022-06-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
7MNS
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BU of 7mns by Molmil
Crystal Structure of the ZnF4 of Nucleoporin NUP358/RanBP2 in complex with Ran-GDP
Descriptor: E3 SUMO-protein ligase RanBP2, GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
Deposit date:2021-05-01
Release date:2022-06-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
7MNV
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BU of 7mnv by Molmil
Crystal Structure of the ZnF8 of Nucleoporin NUP358/RanBP2 in complex with Ran-GDP
Descriptor: E3 SUMO-protein ligase RanBP2, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
Deposit date:2021-05-01
Release date:2022-06-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022

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