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7YPA
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BU of 7ypa by Molmil
Cryo-EM structure of Escherichia coli hairpin-nucleation complex of transcription termination (TTC-hairpin)
Descriptor: DNA (31-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:You, L.L, Zhang, Y.
Deposit date:2022-08-03
Release date:2022-11-16
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Structural basis for intrinsic transcription termination.
Nature, 613, 2023
8Q3B
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BU of 8q3b by Molmil
The closed state of the ASFV apo-RNA polymerase
Descriptor: DNA-directed RNA polymerase RPB1 homolog, DNA-directed RNA polymerase RPB10 homolog, DNA-directed RNA polymerase RPB2 homolog, ...
Authors:Pilotto, S, Sykora, M, Cackett, G, Werner, F.
Deposit date:2023-08-03
Release date:2024-02-14
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Structure of the recombinant RNA polymerase from African Swine Fever Virus.
Nat Commun, 15, 2024
8Q3K
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BU of 8q3k by Molmil
The open state of the ASFV apo-RNA polymerase
Descriptor: DNA-directed RNA polymerase RPB1 homolog, DNA-directed RNA polymerase RPB10 homolog, DNA-directed RNA polymerase RPB2 homolog, ...
Authors:Pilotto, S, Sykora, M, Cackett, G, Werner, F.
Deposit date:2023-08-04
Release date:2024-02-14
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Structure of the recombinant RNA polymerase from African Swine Fever Virus.
Nat Commun, 15, 2024
6NSM
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BU of 6nsm by Molmil
TetR family transcriptional regulator CifR C99T-C107S-C181R Cysteines mutant complexed with 26bp double-strand operator DNA
Descriptor: DNA (26-MER), TetR family transcriptional regulator CifR
Authors:He, S, Simard, A.R, Madden, D.R.
Deposit date:2019-01-25
Release date:2020-01-29
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular basis for the transcriptional regulation of an epoxide-based virulence circuit in Pseudomonas aeruginosa
Biorxiv, 2024
7B7U
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BU of 7b7u by Molmil
Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Fianu, I, Dienemann, C, Aibara, S, Schilbach, S, Cramer, P.
Deposit date:2020-12-11
Release date:2021-05-19
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2.
Commun Biol, 4, 2021
8AD1
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BU of 8ad1 by Molmil
RNA polymerase at U-rich pause bound to RNA putL triple mutant - pause prone, closed clamp state
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Dey, S, Weixlbaumer, A.
Deposit date:2022-07-07
Release date:2022-10-19
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insights into RNA-mediated transcription regulation in bacteria.
Mol.Cell, 82, 2022
1SMY
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BU of 1smy by Molmil
Structural basis for transcription regulation by alarmone ppGpp
Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Artsimovitch, I, Patlan, V, Sekine, S, Vassylyeva, M.N, Hosaka, T, Ochi, K, Yokoyama, S, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-03-10
Release date:2004-05-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for transcription regulation by alarmone ppGpp
Cell(Cambridge,Mass.), 117, 2004
5C44
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BU of 5c44 by Molmil
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G.
Deposit date:2015-06-17
Release date:2015-08-26
Method:X-RAY DIFFRACTION (3.95 Å)
Cite:Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
7ASU
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BU of 7asu by Molmil
Crystal structure of tWHD1 of Rpc5 subunit of human RNA Polymerase III
Descriptor: DNA-directed RNA polymerase III subunit RPC5, ZINC ION
Authors:Vannini, A, Abascal-Palacios, G, Ramsay, E.P.
Deposit date:2020-10-28
Release date:2020-12-30
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structure of human RNA polymerase III.
Nat Commun, 11, 2020
6MGM
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BU of 6mgm by Molmil
Helix-Loop-helix motif of mouse DNA-binding protein inhibitor ID-1
Descriptor: DNA-binding protein inhibitor ID-1
Authors:Benezra, R, Pavletich, N.P, Goldgur, Y, Gall, A.-L.
Deposit date:2018-09-14
Release date:2019-09-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.791 Å)
Cite:A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization.
Cell Rep, 29, 2019
6FLQ
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BU of 6flq by Molmil
CryoEM structure of E.coli RNA polymerase paused elongation complex bound to NusA
Descriptor: DNA (31-MER), DNA (39-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Guo, X, Weixlbaumer, A.
Deposit date:2018-01-26
Release date:2018-03-21
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural Basis for NusA Stabilized Transcriptional Pausing.
Mol. Cell, 69, 2018
5C4X
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BU of 5c4x by Molmil
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G.
Deposit date:2015-06-18
Release date:2015-08-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
6GML
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BU of 6gml by Molmil
Structure of paused transcription complex Pol II-DSIF-NELF
Descriptor: DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Vos, S.M, Farnung, L, Urlaub, H, Cramer, P.
Deposit date:2018-05-27
Release date:2018-09-05
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of paused transcription complex Pol II-DSIF-NELF.
Nature, 560, 2018
5C4A
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BU of 5c4a by Molmil
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Barnes, C.O, Calero, M, Malik, I, Saphr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G.
Deposit date:2015-06-17
Release date:2015-08-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
4TMA
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BU of 4tma by Molmil
Crystal structure of gyrase bound to its inhibitor YacG
Descriptor: DNA gyrase inhibitor YacG, DNA gyrase subunit A, DNA gyrase subunit B, ...
Authors:Vos, S.M, Lyubimov, A.Y, Hershey, D.M, Schoeffler, A.J, Berger, J.M.
Deposit date:2014-05-31
Release date:2014-07-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Direct control of type IIA topoisomerase activity by a chromosomally encoded regulatory protein.
Genes Dev., 28, 2014
8EVJ
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BU of 8evj by Molmil
CX3CR1 nucleosome bound PU.1 and C/EBPa
Descriptor: DNA (167-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
Authors:Guan, R, Bai, Y, Lian, T.
Deposit date:2022-10-20
Release date:2023-11-01
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha.
Nat.Struct.Mol.Biol., 31, 2024
8EVI
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BU of 8evi by Molmil
CX3CR1 nucleosome and PU.1 complex containing disulfide bond mutations
Descriptor: DNA (167-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
Authors:Lian, T, Guan, R, Bai, Y.
Deposit date:2022-10-20
Release date:2023-11-01
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha.
Nat.Struct.Mol.Biol., 31, 2024
8EVH
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BU of 8evh by Molmil
CX3CR1 nucleosome and wild type PU.1 complex
Descriptor: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
Authors:Lian, T, Guan, R, Bai, Y.
Deposit date:2022-10-20
Release date:2023-11-01
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha.
Nat.Struct.Mol.Biol., 31, 2024
8W9E
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BU of 8w9e by Molmil
Cryo-EM structure of the Rpd3S-nucleosome complex from budding yeast in State 2
Descriptor: 3-DNA, 5-DNA, Chromatin modification-related protein EAF3, ...
Authors:Wang, C, Zhan, X.
Deposit date:2023-09-05
Release date:2024-05-15
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures and dynamics of Rpd3S complex bound to nucleosome.
Sci Adv, 10, 2024
8W9F
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BU of 8w9f by Molmil
Cryo-EM structure of the Rpd3S-nucleosome complex from budding yeast in State 3
Descriptor: 3-DNA, 5-DNA, Chromatin modification-related protein EAF3, ...
Authors:Wang, C, Zhan, X.
Deposit date:2023-09-05
Release date:2024-05-15
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structures and dynamics of Rpd3S complex bound to nucleosome.
Sci Adv, 10, 2024
6L8N
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BU of 6l8n by Molmil
Crystal structure of the K. lactis Rad5
Descriptor: DNA repair protein RAD5, ZINC ION
Authors:Shen, M, Xiang, S.
Deposit date:2019-11-06
Release date:2020-11-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis for the multi-activity factor Rad5 in replication stress tolerance.
Nat Commun, 12, 2021
8H0V
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BU of 8h0v by Molmil
RNA polymerase II transcribing a chromatosome (type I)
Descriptor: DNA (261-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Hirano, R, Ehara, H, Tomoya, K, Takizawa, Y, Sekine, S, Kurumizaka, H.
Deposit date:2022-09-30
Release date:2022-12-07
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of RNA polymerase II transcription on the chromatosome containing linker histone H1.
Nat Commun, 13, 2022
8H0W
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BU of 8h0w by Molmil
RNA polymerase II transcribing a chromatosome (type II)
Descriptor: DNA (261-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Hirano, R, Ehara, H, Tomoya, K, Takizawa, Y, Sekine, S, Kurumizaka, H.
Deposit date:2022-09-30
Release date:2022-12-07
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis of RNA polymerase II transcription on the chromatosome containing linker histone H1.
Nat Commun, 13, 2022
8W9D
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BU of 8w9d by Molmil
Cryo-EM structure of the Rpd3S-nucleosome complex from budding yeast in State 1
Descriptor: 3-DNA, 5-DNA, Chromatin modification-related protein EAF3, ...
Authors:Wang, C, Zhan, X.
Deposit date:2023-09-05
Release date:2024-05-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structures and dynamics of Rpd3S complex bound to nucleosome.
Sci Adv, 10, 2024
8HE5
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BU of 8he5 by Molmil
RNA polymerase II elongation complex bound with Rad26 and Elf1, stalled at SHL(-3.5) of the nucleosome
Descriptor: DNA (198-MER), DNA repair protein, DNA-directed RNA polymerase subunit, ...
Authors:Osumi, K, Kujirai, T, Ehara, H, Kinoshita, C, Saotome, M, Kagawa, W, Sekine, S, Takizawa, Y, Kurumizaka, H.
Deposit date:2022-11-07
Release date:2023-07-05
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (6.95 Å)
Cite:Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome.
J.Mol.Biol., 435, 2023

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