Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

8ADV
DownloadVisualize
BU of 8adv by Molmil
Lipidic alpha-synuclein fibril - polymorph L1B
Descriptor: Alpha-synuclein
Authors:Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F.
Deposit date:2022-07-11
Release date:2022-10-12
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:The 3D structure of lipidic fibrils of alpha-synuclein.
Nat Commun, 13, 2022
8ADS
DownloadVisualize
BU of 8ads by Molmil
Lipidic alpha-synuclein fibril - polymorph L2B
Descriptor: Alpha-synuclein
Authors:Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F.
Deposit date:2022-07-11
Release date:2022-10-12
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:The 3D structure of lipidic fibrils of alpha-synuclein.
Nat Commun, 13, 2022
8A4L
DownloadVisualize
BU of 8a4l by Molmil
Lipidic alpha-synuclein fibril - polymorph L2A
Descriptor: Alpha-synuclein
Authors:Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F.
Deposit date:2022-06-12
Release date:2022-08-17
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:The 3D structure of lipidic fibrils of alpha-synuclein.
Nat Commun, 13, 2022
8HZC
DownloadVisualize
BU of 8hzc by Molmil
Formed alpha-synuclein fibrils after incubation with heparin for 1 hour (Hep-remod-2)
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2023-01-08
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Formed alpha-synuclein fibrils after incubation with heparin for 1 hour (Hep-remod-2)
To Be Published
8HZB
DownloadVisualize
BU of 8hzb by Molmil
Formed alpha-synuclein fibrils after incubation with heparin for 1 hour (Hep-remod-1)
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2023-01-08
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Formed alpha-synuclein fibrils after incubation with heparin for 1 hour (Hep-remod-1)
To Be Published
8HZS
DownloadVisualize
BU of 8hzs by Molmil
Formed alpha-synuclein fibrils after incubation with heparin for 3 days (Hep-remod-3)
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2023-01-09
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Formed alpha-synuclein fibrils after incubation with heparin for 3 days (Hep-remod-3)
To Be Published
8F1I
DownloadVisualize
BU of 8f1i by Molmil
SigN RNA polymerase early-melted intermediate bound to mismatch fragment dhsU36mm1 (-12T)
Descriptor: DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Mueller, A.U, Chen, J, Darst, S.A.
Deposit date:2022-11-05
Release date:2023-04-05
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A general mechanism for transcription bubble nucleation in bacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023
8F1J
DownloadVisualize
BU of 8f1j by Molmil
SigN RNA polymerase early-melted intermediate bound to mismatch DNA fragment dhsU36mm2 (-12A)
Descriptor: DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Mueller, A.U, Chen, J, Darst, S.A.
Deposit date:2022-11-05
Release date:2023-04-05
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:A general mechanism for transcription bubble nucleation in bacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023
8F1K
DownloadVisualize
BU of 8f1k by Molmil
SigN RNA polymerase early-melted intermediate bound to full duplex DNA fragment dhsU36 (-12T)
Descriptor: DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Mueller, A.U, Chen, J, Darst, S.A.
Deposit date:2022-11-05
Release date:2023-04-05
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:A general mechanism for transcription bubble nucleation in bacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023
9EUU
DownloadVisualize
BU of 9euu by Molmil
Structure of recombinant alpha-synuclein fibrils 1B capable of seeding GCIs in vivo
Descriptor: Alpha-synuclein
Authors:Burger, D, Kashyrina, M, Lewis, A, De Nuccio, F, Mohammed, I, de La Seigliere, H, van den Heuvel, L, Feuillie, C, Verchere, J, Berbon, M, Arotcarena, M, Retailleau, A, Bezard, E, Laferriere, F, Loquet, A, Bousset, L, Baron, T, Lofrumento, D.D, De Giorgi, F, Stahlberg, H, Ichas, F.
Deposit date:2024-03-28
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (1.93 Å)
Cite:Multiple System Atrophy: Insights from aSyn Fibril Structure
To Be Published
8JO2
DownloadVisualize
BU of 8jo2 by Molmil
Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA
Descriptor: DNA (65-MER), DNA-binding transcriptional regulator BasR, DNA-directed RNA polymerase subunit alpha, ...
Authors:Lou, Y.-C, Huang, H.-Y, Chen, C, Wu, K.-P.
Deposit date:2023-06-06
Release date:2023-08-30
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (2.74 Å)
Cite:Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA.
Nucleic Acids Res., 51, 2023
6L1T
DownloadVisualize
BU of 6l1t by Molmil
Cryo-EM structure of phosphorylated Tyr39 a-synuclein amyloid fibril
Descriptor: Alpha-synuclein
Authors:Liu, C, Li, Y.M, Zhao, K, Lim, Y.J, Liu, Z.Y.
Deposit date:2019-09-30
Release date:2020-08-12
Last modified:2020-09-02
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Parkinson's disease-related phosphorylation at Tyr39 rearranges alpha-synuclein amyloid fibril structure revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 117, 2020
6L1U
DownloadVisualize
BU of 6l1u by Molmil
Cryo-EM structure of phosphorylated Tyr39 alpha-synuclein amyloid fibril
Descriptor: Alpha-synuclein
Authors:Liu, C, Li, Y.M, Zhao, K, Lim, Y.J, Liu, Z.Y.
Deposit date:2019-09-30
Release date:2020-08-12
Last modified:2020-09-02
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Parkinson's disease-related phosphorylation at Tyr39 rearranges alpha-synuclein amyloid fibril structure revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 117, 2020
6LRQ
DownloadVisualize
BU of 6lrq by Molmil
Cryo-EM structure of A53T alpha-synuclein amyloid fibril
Descriptor: Alpha-synuclein
Authors:Sun, Y.P, Zhao, K, Liu, C.
Deposit date:2020-01-16
Release date:2020-04-08
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Cryo-EM structure of full-length alpha-synuclein amyloid fibril with Parkinson's disease familial A53T mutation.
Cell Res., 30, 2020
6E3K
DownloadVisualize
BU of 6e3k by Molmil
Interferon gamma signalling complex with IFNGR1 and IFNGR2
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Jude, K.M, Mendoza, J.L, Garcia, K.C.
Deposit date:2018-07-14
Release date:2019-02-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure of the IFN gamma receptor complex guides design of biased agonists.
Nature, 567, 2019
6E3L
DownloadVisualize
BU of 6e3l by Molmil
Interferon gamma signalling complex with IFNGR1 and IFNGR2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, ...
Authors:Jude, K.M, Mendoza, J.L, Garcia, K.C.
Deposit date:2018-07-14
Release date:2019-02-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structure of the IFN gamma receptor complex guides design of biased agonists.
Nature, 567, 2019
7V4B
DownloadVisualize
BU of 7v4b by Molmil
Heparin-induced alpha-synuclein fibrils polymorph 3
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Sun, Y.P, Liu, C, Li, D.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Heparin-induced alpha-synuclein fibrils polymorph 3
To Be Published
7V4C
DownloadVisualize
BU of 7v4c by Molmil
Heparin-induced alpha-synuclein fibrils polymorph 4
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Sun, Y.P, Liu, C, Li, D.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Heparin-induced alpha-synuclein fibrils polymorph 4
To Be Published
7V47
DownloadVisualize
BU of 7v47 by Molmil
Type 1A alpha-synuclein fibril seeded by cerebrospinal fluid from a preclinical Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7V48
DownloadVisualize
BU of 7v48 by Molmil
Type 1D alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7V4A
DownloadVisualize
BU of 7v4a by Molmil
Heparin-induced alpha-synuclein fibrils polymorph 1
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Sun, Y.P, Liu, C, Li, D.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Heparin-induced alpha-synuclein fibrils polymorph 1
To Be Published
7V4D
DownloadVisualize
BU of 7v4d by Molmil
Heparin-remodelled alpha-synuclein fibrils
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Sun, Y.P, Xia, W.C, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Heparin-remodelled alpha-synuclein fibrils
To Be Published
7V49
DownloadVisualize
BU of 7v49 by Molmil
Type 4 alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
1XCV
DownloadVisualize
BU of 1xcv by Molmil
Crystal Structure Of (H79AC102D)Dtxr complexed with Nickel(II)
Descriptor: Diphtheria toxin repressor mutant, NICKEL (II) ION
Authors:D'aquino, J.A, Ringe, D.
Deposit date:2004-09-03
Release date:2005-08-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanism of metal ion activation of the diphtheria toxin repressor DtxR.
Proc.Natl.Acad.Sci.USA, 102, 2005
7C1D
DownloadVisualize
BU of 7c1d by Molmil
Cryo-EM structure of the hE46K cross-seeded hWT alpha-synuclein fibril
Descriptor: Alpha-synuclein
Authors:Sun, Y.P, Zhao, K, Liu, C.
Deposit date:2020-05-03
Release date:2021-05-05
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Wild-type alpha-synuclein inherits the structure and exacerbated neuropathology of E46K mutant fibril strain by cross-seeding.
Proc.Natl.Acad.Sci.USA, 118, 2021

223532

PDB entries from 2024-08-07

PDB statisticsPDBj update infoContact PDBjnumon