3ZDM
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![BU of 3zdm by Molmil](/molmil-images/mine/3zdm) | Crystal structure of the Sgt2 N domain and the Get5 UBL domain complex | Descriptor: | SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT- CONTAINING PROTEIN 2, UBIQUITIN-LIKE PROTEIN MDY2 | Authors: | Tung, J.-Y, Li, Y.-C, Hsiao, C.-D. | Deposit date: | 2012-11-29 | Release date: | 2013-10-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.803 Å) | Cite: | Structure of the Sgt2 Dimerization Domain Complexed with the Get5 Ubl Domain Involved in the Targeting of Tail-Anchored Membrane Proteins to the Endoplasmic Reticulum. Acta Crystallogr.,Sect.D, 69, 2013
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4I6N
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![BU of 4i6n by Molmil](/molmil-images/mine/4i6n) | Crystal structure of Trichinella spiralis UCH37 catalytic domain bound to Ubiquitin vinyl methyl ester | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, METHYL 4-AMINOBUTANOATE, SODIUM ION, ... | Authors: | Morrow, M.E, Ronau, J.A, White, R.R, Artavanis-Tsakonas, K, Das, C. | Deposit date: | 2012-11-29 | Release date: | 2013-05-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.701 Å) | Cite: | Stabilization of an Unusual Salt Bridge in Ubiquitin by the Extra C-Terminal Domain of the Proteasome-Associated Deubiquitinase UCH37 as a Mechanism of Its Exo Specificity. Biochemistry, 52, 2013
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4I6L
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![BU of 4i6l by Molmil](/molmil-images/mine/4i6l) | |
2M17
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![BU of 2m17 by Molmil](/molmil-images/mine/2m17) | |
4HXD
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![BU of 4hxd by Molmil](/molmil-images/mine/4hxd) | |
4HK2
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![BU of 4hk2 by Molmil](/molmil-images/mine/4hk2) | U7Ub25.2540 | Descriptor: | SULFATE ION, Ubiquitin | Authors: | Murray, J.M, Rouge, L. | Deposit date: | 2012-10-14 | Release date: | 2012-11-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Potent and selective inhibitors of USP7/HAUSP activity by protein conformational stabilization to be published
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4HJK
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![BU of 4hjk by Molmil](/molmil-images/mine/4hjk) | U7Ub7 Disulfide variant | Descriptor: | PHOSPHATE ION, Ubiquitin | Authors: | Murray, J.M, Rouge, L. | Deposit date: | 2012-10-12 | Release date: | 2012-11-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.784 Å) | Cite: | Potent and selective inhibitors of USP7/HAUSP activity by protein conformational stabilization to be published
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4HCP
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![BU of 4hcp by Molmil](/molmil-images/mine/4hcp) | |
4HCN
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![BU of 4hcn by Molmil](/molmil-images/mine/4hcn) | Crystal structure of Burkholderia pseudomallei effector protein CHBP in complex with ubiquitin | Descriptor: | DI(HYDROXYETHYL)ETHER, FORMIC ACID, PHOSPHATE ION, ... | Authors: | Yao, Q, Cui, J, Zhu, Y, Shao, F. | Deposit date: | 2012-09-30 | Release date: | 2012-11-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural mechanism of ubiquitin and NEDD8 deamidation catalyzed by bacterial effectors that induce macrophage-specific apoptosis. Proc.Natl.Acad.Sci.USA, 109, 2012
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4BBN
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![BU of 4bbn by Molmil](/molmil-images/mine/4bbn) | NEDD4 HECT-Ub:Ub complex | Descriptor: | E3 UBIQUITIN-PROTEIN LIGASE NEDD4, POLYUBIQUITIN-B | Authors: | Maspero, E, Valentini, E, Mari, S, Cecatiello, V, Polo, S, Pasqualato, S. | Deposit date: | 2012-09-27 | Release date: | 2013-05-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structure of a Ubiquitin-Loaded Hect Ligase Reveals the Molecular Basis for Catalytic Priming Nat.Struct.Mol.Biol., 20, 2013
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2LZ6
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![BU of 2lz6 by Molmil](/molmil-images/mine/2lz6) | Distinct ubiquitin binding modes exhibited by sh3 domains: molecular determinants and functional implications | Descriptor: | CD2-associated protein, Ubiquitin | Authors: | Ortega-Roldan, J, Azuaga, A, Blackledge, M, Van Nuland, N. | Deposit date: | 2012-09-24 | Release date: | 2013-10-02 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Distinct Ubiquitin Binding Modes Exhibited by SH3 Domains: Molecular Determinants and Functional Implications. Plos One, 8, 2013
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4B9K
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![BU of 4b9k by Molmil](/molmil-images/mine/4b9k) | pVHL-ELOB-ELOC complex_(2S,4R)-1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide bound | Descriptor: | (2S,4R)-1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide, ACETATE ION, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ... | Authors: | Buckley, D.L, Gustafson, J.L, VanMolle, I, Roth, A.G, SeopTae, H, Gareiss, P.C, Jorgensen, W.L, Ciulli, A, Crews, C.M. | Deposit date: | 2012-09-05 | Release date: | 2012-10-24 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Small-Molecule Inhibitors of the Interaction between the E3 Ligase Vhl and Hif1 Alpha Angew.Chem.Int.Ed.Engl., 51, 2012
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4B95
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![BU of 4b95 by Molmil](/molmil-images/mine/4b95) | pVHL-EloB-EloB-EloC complex_(2S,4R)-1-(2-chlorophenyl)carbonyl-N-[(4-chlorophenyl)methyl]-4-oxidanyl-pyrrolidine-2-carboxamide bound | Descriptor: | (2S,4R)-1-(2-chlorophenyl)carbonyl-N-[(4-chlorophenyl)methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, ACETATE ION, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ... | Authors: | Buckley, D.L, Gustafson, J.L, VanMolle, I, Roth, A.G, SeopTae, H, Gareiss, P.C, Jorgensen, W.L, Ciulli, A, Crews, C.M. | Deposit date: | 2012-08-31 | Release date: | 2012-10-24 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Small-Molecule Inhibitors of the Interaction between the E3 Ligase Vhl and Hif1Alpha Angew.Chem.Int.Ed.Engl., 51, 2012
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4GU2
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![BU of 4gu2 by Molmil](/molmil-images/mine/4gu2) | |
4GSW
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![BU of 4gsw by Molmil](/molmil-images/mine/4gsw) | |
2LXA
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![BU of 2lxa by Molmil](/molmil-images/mine/2lxa) | |
2LXC
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![BU of 2lxc by Molmil](/molmil-images/mine/2lxc) | |
4GOC
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![BU of 4goc by Molmil](/molmil-images/mine/4goc) | |
4GIV
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![BU of 4giv by Molmil](/molmil-images/mine/4giv) | |
4V8T
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![BU of 4v8t by Molmil](/molmil-images/mine/4v8t) | Cryo-EM Structure of the 60S Ribosomal Subunit in Complex with Arx1 and Rei1 | Descriptor: | 25S RIBOSOMAL RNA, 5.8S RIBOSOMAL RNA, 5S RIBOSOMAL RNA, ... | Authors: | Greber, B.J, Boehringer, D, Montellese, C, Ban, N. | Deposit date: | 2012-08-07 | Release date: | 2014-07-09 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.1 Å) | Cite: | Cryo-Em Structures of Arx1 and Maturation Factors Rei1 and Jjj1 Bound to the 60S Ribosomal Subunit Nat.Struct.Mol.Biol., 19, 2012
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4GGQ
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![BU of 4ggq by Molmil](/molmil-images/mine/4ggq) | |
2LWP
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![BU of 2lwp by Molmil](/molmil-images/mine/2lwp) | |
4G50
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![BU of 4g50 by Molmil](/molmil-images/mine/4g50) | |
2LVQ
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![BU of 2lvq by Molmil](/molmil-images/mine/2lvq) | gp78CUE domain bound to the proximal ubiquitin of K48-linked diubiquitin | Descriptor: | E3 ubiquitin-protein ligase AMFR, Ubiquitin | Authors: | Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R. | Deposit date: | 2012-07-09 | Release date: | 2012-11-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains. Structure, 20, 2012
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2LVO
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![BU of 2lvo by Molmil](/molmil-images/mine/2lvo) | Structure of the gp78CUE domain bound to monubiquitin | Descriptor: | E3 ubiquitin-protein ligase AMFR, Ubiquitin | Authors: | Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R. | Deposit date: | 2012-07-09 | Release date: | 2012-11-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains. Structure, 20, 2012
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