NEDD4 HECT-Ub:Ub complex

Summary for 4BBN

Related2XBB 2XBF 4BE8
DescriptorE3 UBIQUITIN-PROTEIN LIGASE NEDD4, POLYUBIQUITIN-B, ... (4 entities in total)
Functional Keywordsligase-signaling protein complex, ligase, ubiquitination, ligase/signaling protein
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm (By similarity) P46934 P0CG53 P0CG53
Total number of polymer chains3
Total molecular weight62830.66
Maspero, E.,Valentini, E.,Mari, S.,Cecatiello, V.,Polo, S.,Pasqualato, S. (deposition date: 2012-09-27, release date: 2013-05-01, Last modification date: 2013-09-25)
Primary citation
Maspero, E.,Valentini, E.,Mari, S.,Cecatiello, V.,Soffientini, P.,Pasqualato, S.,Polo, S.
Structure of a Ubiquitin-Loaded Hect Ligase Reveals the Molecular Basis for Catalytic Priming
Nat.Struct.Mol.Biol., 20:696-, 2013
PubMed: 23644597 (PDB entries with the same primary citation)
DOI: 10.1038/NSMB.2566
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2251507.1%8.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report