PDB: 19260 resultsInfo pagesStatus searchChemie searchBIRD

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4G6O	Crystal Structure of the ERK2 Descriptor: 1,2-ETHANEDIOL, 4-{4-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl}-N-(2,3-dihydro-1-benzofuran-5-ylmethyl)-1H-pyrrole-2-carboxamide, Mitogen-activated protein kinase 1, ... Authors: Kang, Y.N, Stuckey, J.A, Xie, X. Deposit date: 2012-07-19 Release date: 2012-09-19 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal Structure of the ERK2 complexed with E28 to be published
4E0P	Protelomerase tela covalently complexed with substrate DNA Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*TP*AP*AP*TP*AP*AP*CP*AP*AP*TP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*GP*AP*TP*AP*TP*TP*GP*TP*TP*AP*TP*TP*AP*TP*G)-3'), ... Authors: Shi, K, Aihara, H. Deposit date: 2012-03-05 Release date: 2013-02-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: An enzyme-catalyzed multistep DNA refolding mechanism in hairpin telomere formation. Plos Biol., 11, 2013
3P3X	Crystal Structure of the Cytochrome P450 Monooxygenase AurH (nterm-AurH-I) from Streptomyces Thioluteus Descriptor: CHLORIDE ION, Cytochrome P450, GLYCEROL, ... Authors: Zocher, G, Richter, M.E.A, Mueller, U, Hertweck, C. Deposit date: 2010-10-05 Release date: 2011-02-16 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural fine-tuning of a multifunctional cytochrome p450 monooxygenase. J.Am.Chem.Soc., 133, 2011
4E1N	Crystal Structure of HIV-1 Integrase with a non-catayltic site inhibitor Descriptor: (2S)-tert-butoxy[4-(8-fluoro-5-methyl-3,4-dihydro-2H-chromen-6-yl)-2-methylquinolin-3-yl]ethanoic acid, HIV-1 integrase Authors: Lansdon, E.B. Deposit date: 2012-03-06 Release date: 2012-04-25 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2 Å) Cite: New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action. J.Biol.Chem., 287, 2012
4E2T	Crystal Structures of RadA intein from Pyrococcus horikoshii Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Pho radA intein Authors: Oeemig, J.S, Zhou, D, Kajander, T, Wlodawer, A, Iwai, H. Deposit date: 2012-03-09 Release date: 2012-05-16 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.75 Å) Cite: NMR and Crystal Structures of the Pyrococcus horikoshii RadA Intein Guide a Strategy for Engineering a Highly Efficient and Promiscuous Intein. J.Mol.Biol., 421, 2012
4E0J	Protelomerase tela R255A mutant complexed with DNA hairpin product Descriptor: CHLORIDE ION, DNA (5'-D(*CP*AP*TP*AP*AP*TP*AP*AP*CP*AP*AP*TP*A)-3'), DNA (5'-D(*TP*CP*AP*TP*GP*AP*TP*AP*TP*TP*GP*TP*TP*AP*TP*TP*AP*TP*G)-3'), ... Authors: Shi, K, Aihara, H. Deposit date: 2012-03-04 Release date: 2013-02-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.3 Å) Cite: An enzyme-catalyzed multistep DNA refolding mechanism in hairpin telomere formation. Plos Biol., 11, 2013
3P59	First Crystal Structure of a RNA Nanosquare Descriptor: COBALT HEXAMMINE(III), MAGNESIUM ION, RNA (5'-R(*CP*CP*GP*GP*AP*GP*GP*AP*AP*CP*UP*AP*CP*(5BU)P*G)-3'), ... Authors: Dibrov, S, Hermann, T, McLean, J, Parsons, J. Deposit date: 2010-10-08 Release date: 2011-04-06 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.1793 Å) Cite: Self-assembling RNA square. Proc.Natl.Acad.Sci.USA, 108, 2011
3P4F	Structural and biochemical insights into MLL1 core complex assembly and regulation. Descriptor: Histone-lysine N-methyltransferase MLL, Retinoblastoma-binding protein 5, WD repeat-containing protein 5 Authors: Avdic, V, Zhang, P, Lanouette, S, Groulx, A, Tremblay, V, Brunzelle, J.B, Couture, J.-F. Deposit date: 2010-10-06 Release date: 2010-12-08 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural and biochemical insights into MLL1 core complex assembly. Structure, 19, 2011
4E0G	Protelomerase tela/DNA hairpin product/vanadate complex Descriptor: DNA (5'-D(*CP*AP*TP*AP*AP*TP*AP*AP*CP*AP*AP*TP*A)-3'), DNA (5'-D(*TP*CP*AP*TP*GP*AP*TP*AP*TP*TP*GP*TP*TP*AP*TP*TP*AP*TP*G)-3'), Protelomerase, ... Authors: Shi, K, Aihara, H. Deposit date: 2012-03-03 Release date: 2013-02-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.2 Å) Cite: An enzyme-catalyzed multistep DNA refolding mechanism in hairpin telomere formation. Plos Biol., 11, 2013
4E0Z	Protelomerase tela R205A covalently complexed with substrate DNA Descriptor: DNA (5'-D(*CP*AP*TP*AP*AP*TP*AP*AP*CP*AP*AP*TP*A)-3'), DNA (5'-D(*TP*CP*A*TP*GP*AP*TP*AP*TP*TP*GP*TP*TP*AP*TP*TP*AP*TP*G)-3'), GLYCEROL, ... Authors: Shi, K, Aihara, H. Deposit date: 2012-03-05 Release date: 2013-02-13 Method: X-RAY DIFFRACTION (2.42 Å) Cite: An enzyme-catalyzed multistep DNA refolding mechanism in hairpin telomere formation. Plos Biol., 11, 2013
3PA0	Crystal Structure of Chiral Gamma-PNA with Complementary DNA Strand: Insight Into the Stability and Specificity of Recognition an Conformational Preorganization Descriptor: 1,2-ETHANEDIOL, DNA 5'-D(*AP*TP*CP*TP*GP*TP*GP*GP*TP*C)-3', PEPTIDE NUCLEIC ACID, ... Authors: Yeh, J.I, Shivachev, B, Du, S. Deposit date: 2010-10-18 Release date: 2010-12-29 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of chiral gammaPNA with complementary DNA strand: insights into the stability and specificity of recognition and conformational preorganization. J.Am.Chem.Soc., 132, 2010
3P3Z	Crystal Structure of the Cytochrome P450 Monooxygenase AurH from Streptomyces Thioluteus in Complex with Ancymidol Descriptor: (S)-cyclopropyl(4-methoxyphenyl)pyrimidin-5-ylmethanol, CHLORIDE ION, Cytochrome P450, ... Authors: Zocher, G, Richter, M.E.A, Mueller, U, Hertweck, C. Deposit date: 2010-10-05 Release date: 2011-02-16 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural fine-tuning of a multifunctional cytochrome p450 monooxygenase. J.Am.Chem.Soc., 133, 2011
4FUY	Crystal Structure of the ERK2 complexed with EK2 Descriptor: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, SULFATE ION, ... Authors: Kang, Y.N, Stuckey, J.A, Xie, X. Deposit date: 2012-06-28 Release date: 2012-08-22 Last modified: 2014-09-24 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structure of the ERK2 complexed with EK2 TO BE PUBLISHED
4FV9	Crystal Structure of the ERK2 complexed with E71 Descriptor: 1,2-ETHANEDIOL, 3-[4-(2,3-difluorophenyl)-1,2-oxazol-5-yl]-5-(pyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine, Mitogen-activated protein kinase 1, ... Authors: Kang, Y.N, Stuckey, J.A, Xie, X. Deposit date: 2012-06-29 Release date: 2012-08-29 Last modified: 2014-09-24 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Crystal Structure of the ERK2 complexed with E71 TO BE PUBLISHED
4FYR	Human aminopeptidase N (CD13) in complex with bestatin Descriptor: 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Wong, A.H, Rini, J.M. Deposit date: 2012-07-05 Release date: 2012-09-05 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.91 Å) Cite: The X-ray Crystal Structure of Human Aminopeptidase N Reveals a Novel Dimer and the Basis for Peptide Processing. J.Biol.Chem., 287, 2012
4FV4	Crystal Structure of the ERK2 complexed with EK7 Descriptor: 9-(dimethylamino)-2-[(3-hydroxyphenyl)amino]-5,6-dihydrothieno[3,4-h]quinazoline-7-carbonitrile, GLYCEROL, Mitogen-activated protein kinase 1, ... Authors: Kang, Y.N, Stuckey, J.A, Xie, X. Deposit date: 2012-06-29 Release date: 2012-08-29 Last modified: 2014-09-24 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal Structure of the ERK2 complexed with EK7 TO BE PUBLISHED
4GDK	Crystal Structure of Human Atg12~Atg5 Conjugate in Complex with an N-terminal Fragment of Atg16L1 Descriptor: Autophagy protein 5, Autophagy-related protein 16-1, SODIUM ION, ... Authors: Otomo, C, Metlagel, Z, Takaesu, G, Otomo, T. Deposit date: 2012-07-31 Release date: 2012-12-05 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy. Nat.Struct.Mol.Biol., 20, 2013
3P3L	Crystal Structure of the Cytochrome P450 monooxygenase AurH (wildtype) from Streptomyces Thioluteus Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Cytochrome P450, ... Authors: Zocher, G, Richter, M.E.A, Mueller, U, Hertweck, C. Deposit date: 2010-10-05 Release date: 2011-02-16 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural fine-tuning of a multifunctional cytochrome p450 monooxygenase. J.Am.Chem.Soc., 133, 2011
4DWP	SeMet protelomerase tela covalently complexed with substrate DNA Descriptor: DNA (5'-D(*CP*AP*TP*GP*AP*TP*AP*TP*TP*GP*TP*TP*AP*TP*TP*GP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*AP*CP*AP*AP*TP*AP*AP*CP*AP*AP*TP*AP*T)-3'), Protelomerase, ... Authors: Shi, K, Aihara, H. Deposit date: 2012-02-26 Release date: 2013-02-13 Method: X-RAY DIFFRACTION (2.35 Å) Cite: An enzyme-catalyzed multistep DNA refolding mechanism in hairpin telomere formation. Plos Biol., 11, 2013
3PUW	Crystal Structure of an outward-facing MBP-Maltose transporter complex bound to ADP-AlF4 Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Oldham, M.L, Chen, J. Deposit date: 2010-12-06 Release date: 2011-08-10 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Snapshots of the maltose transporter during ATP hydrolysis. Proc.Natl.Acad.Sci.USA, 108, 2011
4DY7	Crystal structures of protease nexin-1 in complex with S195A thrombin Descriptor: ACETATE ION, CALCIUM ION, Glia-derived nexin, ... Authors: Huntington, J.A, Li, W. Deposit date: 2012-02-28 Release date: 2012-08-15 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism. Blood, 120, 2012
3PDY	Structure of the third and fourth spectrin repeats of the plakin domain of plectin Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Plectin Authors: Ortega, E, de Pereda, J.M. Deposit date: 2010-10-25 Release date: 2011-02-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.2182 Å) Cite: The Structure of the Plakin Domain of Plectin Reveals a Non-canonical SH3 Domain Interacting with Its Fourth Spectrin Repeat. J.Biol.Chem., 286, 2011
3PE0	Structure of the central region of the plakin domain of plectin Descriptor: CALCIUM ION, Plectin Authors: Ortega, E, de Pereda, J.M. Deposit date: 2010-10-25 Release date: 2011-02-02 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.95 Å) Cite: The Structure of the Plakin Domain of Plectin Reveals a Non-canonical SH3 Domain Interacting with Its Fourth Spectrin Repeat. J.Biol.Chem., 286, 2011
4FEP	Crystal structure of the A24U/U25A/A46G/C74U mutant xpt-pbuX guanine riboswitch aptamer domain in complex with 2,6-diaminopurine Descriptor: 9H-PURINE-2,6-DIAMINE, A24U/U25A/A46G/C74U mutant of the B. subtilis xpt-pbuX guanine riboswitch aptamer domain, COBALT HEXAMMINE(III) Authors: Stoddard, C.D, Trausch, J.J, Widmann, J, Marcano, J, Knight, R, Batey, R.T. Deposit date: 2012-05-30 Release date: 2013-02-27 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Nucleotides Adjacent to the Ligand-Binding Pocket are Linked to Activity Tuning in the Purine Riboswitch. J.Mol.Biol., 425, 2013
4FE5	Crystal structure of the xpt-pbuX guanine riboswitch aptamer domain in complex with hypoxanthine Descriptor: ACETATE ION, COBALT HEXAMMINE(III), HYPOXANTHINE, ... Authors: Stoddard, C.D, Trausch, J.J, Widmann, J, Marcano, J, Knight, R, Batey, R.T. Deposit date: 2012-05-29 Release date: 2012-06-27 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.32 Å) Cite: Structure of a natural guanine-responsive riboswitch complexed with the metabolite hypoxanthine. Nature, 432, 2004

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