3PA0

Crystal Structure of Chiral Gamma-PNA with Complementary DNA Strand: Insight Into the Stability and Specificity of Recognition an Conformational Preorganization

Summary for 3PA0

• Entry DOI: 10.2210/pdb3pa0/pdb
• Descriptor: DNA 5'-D(*AP*TP*CP*TP*GP*TP*GP*GP*TP*C)-3', PEPTIDE NUCLEIC ACID, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: gamma-pna, dna, peptide nucleic acid-dna complex, peptide nucleic acid/dna
• Total number of polymer chains: 4
• Total formula weight: 12399.29

Authors

Yeh, J.I.,Shivachev, B.,Du, S. (deposition date: 2010-10-18, release date: 2010-12-29, Last modification date: 2023-11-15)

• Primary citation: Yeh, J.I.,Shivachev, B.,Rapireddy, S.,Crawford, M.J.,Gil, R.R.,Du, S.,Madrid, M.,Ly, D.H.; Crystal structure of chiral gammaPNA with complementary DNA strand: insights into the stability and specificity of recognition and conformational preorganization.; J.Am.Chem.Soc., 132:10717-10727, 2010; PubMed: 20681704; DOI: 10.1021/ja907225d

Experimental method

X-RAY DIFFRACTION (1.6 Å)