4FYR

Human aminopeptidase N (CD13) in complex with bestatin

Summary for 4FYR

Entry DOI	10.2210/pdb4fyr/pdb
Related	4FYQ 4FYS 4FYT
Descriptor	Aminopeptidase N, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
Functional Keywords	metalloprotease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	107204.60
Authors	Wong, A.H.,Rini, J.M. (deposition date: 2012-07-05, release date: 2012-09-05, Last modification date: 2020-07-29)
Primary citation	Wong, A.H.,Zhou, D.,Rini, J.M. The X-ray Crystal Structure of Human Aminopeptidase N Reveals a Novel Dimer and the Basis for Peptide Processing. J.Biol.Chem., 287:36804-36813, 2012 Cited by PubMed: 22932899 DOI: 10.1074/jbc.M112.398842 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.91 Å)

Structure validation