5XA6
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6AYF
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![BU of 6ayf by Molmil](/molmil-images/mine/6ayf) | TRPML3/ML-SA1 complex at pH 7.4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-3 | Authors: | Zhou, X, Li, M, Su, D, Jia, Q, Li, H, Li, X, Yang, J. | Deposit date: | 2017-09-08 | Release date: | 2017-11-08 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.62 Å) | Cite: | Cryo-EM structures of the human endolysosomal TRPML3 channel in three distinct states. Nat. Struct. Mol. Biol., 24, 2017
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6ATL
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![BU of 6atl by Molmil](/molmil-images/mine/6atl) | Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox | Descriptor: | CITRIC ACID, Potassium channel toxin alpha-KTx 4.2, SULFATE ION | Authors: | Gewe, M.M, Rupert, P, Strong, R.K. | Deposit date: | 2017-08-29 | Release date: | 2018-02-28 | Last modified: | 2018-03-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Screening, large-scale production and structure-based classification of cystine-dense peptides. Nat. Struct. Mol. Biol., 25, 2018
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3LX5
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![BU of 3lx5 by Molmil](/molmil-images/mine/3lx5) | Crystal structure of mGMPPNP-bound NFeoB from S. thermophilus | Descriptor: | 2-amino-9-(5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]-3-O-{[2-(methylamino)phenyl]carbonyl}-beta-D-erythro-pentofuranosyl-2-ulose)-1,9-dihydro-6H-purin-6-one, Ferrous iron uptake transporter protein B, GLYCEROL, ... | Authors: | Ash, M.R, Guilfoyle, A, Maher, M.J, Clarke, R.J, Guss, J.M, Jormakka, M. | Deposit date: | 2010-02-24 | Release date: | 2010-03-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Potassium-activated GTPase reaction in the G Protein-coupled ferrous iron transporter B. J.Biol.Chem., 285, 2010
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3LX8
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![BU of 3lx8 by Molmil](/molmil-images/mine/3lx8) | Crystal structure of GDP-bound NFeoB from S. thermophilus | Descriptor: | Ferrous iron uptake transporter protein B, GUANOSINE-5'-DIPHOSPHATE | Authors: | Ash, M.R, Guilfoyle, A, Maher, M.J, Clarke, R.J, Guss, J.M, Jormakka, M. | Deposit date: | 2010-02-24 | Release date: | 2010-03-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Potassium-activated GTPase reaction in the G Protein-coupled ferrous iron transporter B. J.Biol.Chem., 285, 2010
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6EID
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![BU of 6eid by Molmil](/molmil-images/mine/6eid) | Crystal structure of wild-type Channelrhodopsin 2 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Archaeal-type opsin 2, PHOSPHATE ION, ... | Authors: | Borshchevskiy, V, Kovalev, K, Volkov, O, Polovinkin, V, Marin, E, Balandin, T, Astashkin, R, Bamann, C, Bueldt, G, Willlbold, D, Popov, A, Bamberg, E, Gordeliy, V. | Deposit date: | 2017-09-19 | Release date: | 2017-12-06 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Structural insights into ion conduction by channelrhodopsin 2. Science, 358, 2017
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6AU7
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![BU of 6au7 by Molmil](/molmil-images/mine/6au7) | Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox | Descriptor: | GLYCEROL, Potassium channel toxin gamma-KTx 2.2, SULFATE ION | Authors: | Gewe, M.M, Rupert, P, Strong, R.K. | Deposit date: | 2017-08-30 | Release date: | 2018-02-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Screening, large-scale production and structure-based classification of cystine-dense peptides. Nat. Struct. Mol. Biol., 25, 2018
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6AUP
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![BU of 6aup by Molmil](/molmil-images/mine/6aup) | Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox | Descriptor: | GLYCEROL, Potassium channel toxin gamma-KTx 2.2, SULFATE ION | Authors: | Gewe, M.M, Rupert, P, Strong, R.K. | Deposit date: | 2017-09-01 | Release date: | 2018-02-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Screening, large-scale production and structure-based classification of cystine-dense peptides. Nat. Struct. Mol. Biol., 25, 2018
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1LSU
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![BU of 1lsu by Molmil](/molmil-images/mine/1lsu) | KTN Bsu222 Crystal Structure in Complex with NADH | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Conserved hypothetical protein yuaA | Authors: | Roosild, T.P, Miller, S, Booth, I.R, Choe, S. | Deposit date: | 2002-05-18 | Release date: | 2002-07-03 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | A mechanism of regulating transmembrane potassium flux through a ligand-mediated conformational switch. Cell(Cambridge,Mass.), 109, 2002
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2FQC
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![BU of 2fqc by Molmil](/molmil-images/mine/2fqc) | Solution structure of conotoxin pl14a | Descriptor: | Alpha/kappa-conotoxin pl14a | Authors: | Craik, D.J, Daly, N.L. | Deposit date: | 2006-01-18 | Release date: | 2006-07-18 | Last modified: | 2020-06-24 | Method: | SOLUTION NMR | Cite: | A Novel Conotoxin Inhibitor of Kv1.6 Channel and nAChR Subtypes Defines a New Superfamily of Conotoxins Biochemistry, 45, 2006
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3JC2
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3C33
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4LFS
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![BU of 4lfs by Molmil](/molmil-images/mine/4lfs) | High resolution x-ray structure of racemic ShK toxin | Descriptor: | CHLORIDE ION, GLYCEROL, Potassium channel toxin ShK | Authors: | Dang, B, Kubota, T, Mandal, K, Bezanilla, F, Kent, S.B.H. | Deposit date: | 2013-06-27 | Release date: | 2013-08-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (0.97 Å) | Cite: | Native Chemical Ligation at Asx-Cys, Glx-Cys: Chemical Synthesis and High-Resolution X-ray Structure of ShK Toxin by Racemic Protein Crystallography. J.Am.Chem.Soc., 135, 2013
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5DQQ
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![BU of 5dqq by Molmil](/molmil-images/mine/5dqq) | Structure, inhibition and regulation of two-pore channel TPC1 from Arabidopsis thaliana | Descriptor: | CALCIUM ION, PALMITIC ACID, Two pore calcium channel protein 1, ... | Authors: | Kintzer, A.F, Stroud, R.M. | Deposit date: | 2015-09-15 | Release date: | 2016-03-09 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.872 Å) | Cite: | Structure, inhibition and regulation of two-pore channel TPC1 from Arabidopsis thaliana Nature, 531, 2016
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2M9L
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![BU of 2m9l by Molmil](/molmil-images/mine/2m9l) | Solution structure of protoxin-1 | Descriptor: | Beta-theraphotoxin-Tp1a | Authors: | Daly, N. | Deposit date: | 2013-06-13 | Release date: | 2014-04-30 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1-S4 gating domain. Curr.Biol., 24, 2014
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4FR3
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![BU of 4fr3 by Molmil](/molmil-images/mine/4fr3) | Crystal structure of human 14-3-3 sigma in complex with TASK-3 peptide and stabilizer 16-O-Me-FC-H | Descriptor: | (4R,5R,6R,6aS,9S,9aE,10aR)-5-hydroxy-9-(methoxymethyl)-6,10a-dimethyl-3-(propan-2-yl)-1,2,4,5,6,6a,7,8,9,10a-decahydrodicyclopenta[a,d][8]annulen-4-yl alpha-D-glucopyranoside, 14-3-3 protein sigma, MAGNESIUM ION, ... | Authors: | Ottmann, C, Anders, C, Schumacher, B. | Deposit date: | 2012-06-26 | Release date: | 2013-05-08 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of k(+) channels at the cell surface. Chem.Biol., 20, 2013
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2KIR
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![BU of 2kir by Molmil](/molmil-images/mine/2kir) | Solution structure of a designer toxin, mokatoxin-1 | Descriptor: | Designer toxin | Authors: | Biancalana, M, Koide, A, Takacs, Z, Goldstein, S, Koide, S. | Deposit date: | 2009-05-07 | Release date: | 2009-12-29 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | A designer ligand specific for Kv1.3 channels from a scorpion neurotoxin-based library. Proc.Natl.Acad.Sci.USA, 106, 2009
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6CTB
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5NC8
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![BU of 5nc8 by Molmil](/molmil-images/mine/5nc8) | Shewanella denitrificans Kef CTD in AMP bound form | Descriptor: | ADENOSINE MONOPHOSPHATE, Potassium efflux system protein | Authors: | Pliotas, C, Naismith, J.H. | Deposit date: | 2017-03-03 | Release date: | 2017-04-12 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | Adenosine Monophosphate Binding Stabilizes the KTN Domain of the Shewanella denitrificans Kef Potassium Efflux System. Biochemistry, 56, 2017
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3SMO
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![BU of 3smo by Molmil](/molmil-images/mine/3smo) | Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide and stabilizer Fusicoccin J aglycone | Descriptor: | 14-3-3 protein sigma, Fusicoccin J aglycone, MAGNESIUM ION, ... | Authors: | Anders, C, Schumacher, B, Ottmann, C. | Deposit date: | 2011-06-28 | Release date: | 2012-07-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem. Biol., 20, 2013
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3SP5
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![BU of 3sp5 by Molmil](/molmil-images/mine/3sp5) | Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide and stabilizer Cotylenol | Descriptor: | 14-3-3 protein sigma, Cotylenol, MAGNESIUM ION, ... | Authors: | Anders, C, Schumacher, B, Ottmann, C. | Deposit date: | 2011-07-01 | Release date: | 2016-05-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem.Biol., 20, 2013
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3SPR
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![BU of 3spr by Molmil](/molmil-images/mine/3spr) | Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide and stabilizer FC-THF | Descriptor: | 14-3-3 protein sigma, CHLORIDE ION, Fusicoccin A-THF, ... | Authors: | Anders, C, Schumacher, B, Ottmann, C. | Deposit date: | 2011-07-03 | Release date: | 2012-07-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem. Biol., 20, 2013
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3SMM
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![BU of 3smm by Molmil](/molmil-images/mine/3smm) | Crystal structure of human 14-3-3 sigma C38N/N166H in complex with task-3 peptide and stabilizer Fusicoccin J aglycone | Descriptor: | 14-3-3 protein sigma, CHLORIDE ION, Fusicoccin J aglycone, ... | Authors: | Anders, C, Schumacher, B, Ottmann, C. | Deposit date: | 2011-06-28 | Release date: | 2012-07-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem. Biol., 20, 2013
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3SMK
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![BU of 3smk by Molmil](/molmil-images/mine/3smk) | Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide and stabilizer Cotylenin A | Descriptor: | 14-3-3 protein sigma, Cotylenin A, MAGNESIUM ION, ... | Authors: | Anders, C, Schumacher, B, Ottmann, C. | Deposit date: | 2011-06-28 | Release date: | 2012-07-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem. Biol., 20, 2013
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3SMN
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![BU of 3smn by Molmil](/molmil-images/mine/3smn) | Crystal structure of human 14-3-3 sigma C38N/N166H in complex with task-3 peptide and stabilizer Fusicoccin A-THF | Descriptor: | 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... | Authors: | Anders, C, Schumacher, B, Ottmann, C. | Deposit date: | 2011-06-28 | Release date: | 2012-07-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem. Biol., 20, 2013
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