PDB: 46200 resultsInfo pagesStatus searchChemie searchBIRD

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8HUD	Cryo-EM structure of the EvCas9-sgRNA-target DNA ternary complex Descriptor: CRISPR-associated endonuclease Cas9, Non-target DNA strand, Target DNA strand, ... Authors: Tang, N, Wu, Z, Gao, Y, Chen, W, Su, M, Wang, Z, Ji, Q. Deposit date: 2022-12-23 Release date: 2023-12-27 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (3.43 Å) Cite: Molecular Basis and Genome Editing Applications of a Compact Eubacterium ventriosum CRISPR-Cas9 System. Acs Synth Biol, 13, 2024
6BZF	Structure of S. cerevisiae Zip2:Spo16 complex, C2 form Descriptor: Protein ZIP2, Sporulation-specific protein 16 Authors: Arora, K, Corbett, K.D. Deposit date: 2017-12-23 Release date: 2018-02-14 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.286 Å) Cite: The conserved XPF:ERCC1-like Zip2:Spo16 complex controls meiotic crossover formation through structure-specific DNA binding. Nucleic Acids Res., 47, 2019
6TNI	Structure of FANCD2 homodimer Descriptor: Uncharacterized protein Authors: Alcon, P, Shakeel, S, Passmore, L.A. Deposit date: 2019-12-08 Release date: 2020-02-19 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair. Nat.Struct.Mol.Biol., 27, 2020
6JYI	Crystal structure of the PadR-like transcriptional regulator BC1756 from Bacillus cereus Descriptor: Transcriptional repressor PadR Authors: Kim, T.H, Park, S.C, Lee, K.C, Song, W.S, Yoon, S.I. Deposit date: 2019-04-26 Release date: 2019-06-26 Last modified: 2019-07-10 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Structural and DNA-binding studies of the PadR-like transcriptional regulator BC1756 from Bacillus cereus. Biochem.Biophys.Res.Commun., 515, 2019
6DOD	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 200 mM K+ for 360 s at 21 C Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), GLYCEROL, ... Authors: Samara, N.L, Yang, W. Deposit date: 2018-06-09 Release date: 2018-08-15 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.535 Å) Cite: Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
6DOP	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 200 mM K+ for 120 s at 21 C (dataset 1) Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), GLYCEROL, ... Authors: Samara, N.L, Yang, W. Deposit date: 2018-06-09 Release date: 2018-08-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
6DP3	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 10 mM Mg2+ and 75 mM K+ for 40 s at 21 C Descriptor: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of cleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', 5'-R(P*CP*G)-3' portion of cleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', ... Authors: Samara, N.L, Yang, W. Deposit date: 2018-06-09 Release date: 2018-08-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.461 Å) Cite: Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
6DPK	Crystal Structure of Bacillus Halodurans Ribonuclease H1 K196A in Complex with an RNA/DNA Hybrid: Reaction in 4 mM Mn2+ and 200 mM K+ for 240 s at 21 C Descriptor: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of cleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', 5'-R(P*CP*G)-3' portion of cleaved RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), ... Authors: Samara, N.L, Yang, W. Deposit date: 2018-06-09 Release date: 2018-08-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.391 Å) Cite: Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
6DOH	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Soak in 0.5 mM EGTA and 200 mM K+ at 21 C Descriptor: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of intact RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), 5'-R(P*CP*G)-3' portion of intact RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), ... Authors: Samara, N.L, Yang, W. Deposit date: 2018-06-09 Release date: 2018-08-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.363 Å) Cite: Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
6DP1	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 5 mM Mg2+ and 75 mM K+ for 40 s at 21 C Descriptor: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of uncleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', 5'-R(P*CP*G)-3' portion of uncleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', ... Authors: Samara, N.L, Yang, W. Deposit date: 2018-06-09 Release date: 2018-08-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
4M94	d(ATCCGTTATAACGGAT) complexed with Moloney Murine Leukemia virus reverse transcriptase catalytic fragment Descriptor: 1,2-ETHANEDIOL, 5' d(ATCCGttA) 3', 5' d(TAACGGAT) 3', ... Authors: Singh, I. Deposit date: 2013-08-14 Release date: 2014-03-12 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.14 Å) Cite: The structure of an authentic spore photoproduct lesion in DNA suggests a basis for recognition. Acta Crystallogr.,Sect.D, 70, 2014
2KFS	NMR structure of Rv2175c Descriptor: Conserved hypothetical regulatory protein Authors: Barthe, P, Cohen-Gonsaud, M, Roumestand, C, Molle, V. Deposit date: 2009-02-27 Release date: 2009-05-19 Last modified: 2024-05-08 Method: SOLUTION NMR Cite: The Mycobacterium tuberculosis Ser/Thr Kinase Substrate Rv2175c Is a DNA-binding Protein Regulated by Phosphorylation. J.Biol.Chem., 284, 2009
6P7A	CRYSTAL STRUCTURE OF THE FOWLPOX VIRUS HOLLIDAY JUNCTION RESOLVASE Descriptor: CADMIUM ION, Holliday junction resolvase Authors: Li, N, Shi, K, Banerjee, S, Rao, T, Aihara, H. Deposit date: 2019-06-05 Release date: 2020-04-29 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.081 Å) Cite: Structural insights into the promiscuous DNA binding and broad substrate selectivity of fowlpox virus resolvase. Sci Rep, 10, 2020
4MKP	Crystal structure of human cGAS apo form Descriptor: Cyclic GMP-AMP synthase, ZINC ION Authors: Kato, K, Ishii, R, Ishitani, R, Nureki, O. Deposit date: 2013-09-05 Release date: 2013-10-30 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.953 Å) Cite: Structural and Functional Analyses of DNA-Sensing and Immune Activation by Human cGAS Plos One, 8, 2013
5ZYW	The crystal structure of apo-HsMGME1 with Mn2+ Descriptor: GLYCEROL, L(+)-TARTARIC ACID, MANGANESE (II) ION, ... Authors: Yang, C, Gan, J. Deposit date: 2018-05-28 Release date: 2018-09-19 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural insights into DNA degradation by human mitochondrial nuclease MGME1 Nucleic Acids Res., 46, 2018
5JJ3	Refined Structure of the Mature Virion Conformation of P22 Portal Protein Descriptor: Portal protein Authors: Lokareddy, R.K, Sankhala, R.S, Cingolani, G. Deposit date: 2016-04-22 Release date: 2017-02-08 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (7 Å) Cite: Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation. Nat Commun, 8, 2017
5G4Q	H.pylori Beta clamp in complex with 5-chloroisatin Descriptor: 5-chloro-1H-indole-2,3-dione, DNA POLYMERASE III SUBUNIT BETA Authors: Pandey, P, Gourinath, S. Deposit date: 2016-05-16 Release date: 2017-06-21 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization. Antibiotics (Basel), 7, 2018
2MBF	Solution structure of the forkhead domain of Brugia malayi DAF-16a Descriptor: Fork head domain containing protein Authors: Veldkamp, C.T, Peterson, F.C, Casper, S.K, Schoeller, S.J. Deposit date: 2013-07-30 Release date: 2013-09-11 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: The solution structure of the forkhead box-O DNA binding domain of Brugia malayi DAF-16a. Proteins, 82, 2014
8SVZ	Structure of the Francisella response regulator KdpE receiver domain Descriptor: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Two-component response regulator Authors: Milton, M.E, Cavanagh, J. Deposit date: 2023-05-17 Release date: 2024-06-12 Method: X-RAY DIFFRACTION (3.35 Å) Cite: Insights into DNA-binding motifs and mechanisms of Francisella tularensis novicida two-component system response regulator proteins QseB, KdpE, and BfpR. Biochem.Biophys.Res.Commun., 722, 2024
7N3O	Cryo-EM structure of the Cas12k-sgRNA complex Descriptor: Cas12k, Single guide RNA Authors: Chang, L, Li, Z, Xiao, R, Wang, S, Han, R. Deposit date: 2021-06-01 Release date: 2021-09-01 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural basis of target DNA recognition by CRISPR-Cas12k for RNA-guided DNA transposition. Mol.Cell, 81, 2021
8EFY	Structure of double homo-hexameric AAA+ ATPase RuvB motors Descriptor: ADENOSINE-5'-DIPHOSPHATE, Holliday junction ATP-dependent DNA helicase RuvB, MAGNESIUM ION, ... Authors: Shen, Z.F, Rish, A.D, Fu, T.M. Deposit date: 2022-09-10 Release date: 2023-05-10 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Structure of double homo-hexameric AAA+ ATPase RuvB motor binding with DNA substrate To Be Published
8HCG	Crystal structure of mTREX1-dAMP complex Descriptor: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... Authors: Hsiao, Y.Y, Huang, K.W, Wu, C.Y. Deposit date: 2022-11-01 Release date: 2023-11-08 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.799 Å) Cite: Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
8HCE	Crystal structure of mTREX1-CMP complex Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AMMONIUM ION, CYTIDINE-5'-MONOPHOSPHATE, ... Authors: Hsiao, Y.Y, Huang, K.W, Wu, C.Y. Deposit date: 2022-11-01 Release date: 2023-11-08 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.501 Å) Cite: Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
8HCF	Crystal structure of mTREX1-UMP complex Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION, Three-prime repair exonuclease 1, ... Authors: Hsiao, Y.Y, Huang, K.W, Wu, C.Y. Deposit date: 2022-11-01 Release date: 2023-11-08 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
8HCH	Crystal structure of mTREX1-Uridine complex Descriptor: MAGNESIUM ION, Three-prime repair exonuclease 1, URIDINE Authors: Hsiao, Y.Y, Huang, K.W, Wu, C.Y. Deposit date: 2022-11-01 Release date: 2023-11-08 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023

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