1OV6
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![BU of 1ov6 by Molmil](/molmil-images/mine/1ov6) | M64V PNP + ALLO | Descriptor: | 9-(6-DEOXY-BETA-D-ALLOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase | Authors: | Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, P.W, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J. | Deposit date: | 2003-03-25 | Release date: | 2004-02-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system. Chem.Biol., 10, 2003
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1OWC
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![BU of 1owc by Molmil](/molmil-images/mine/1owc) | Three Dimensional Structure Analysis Of The R109L Variant of the Type II Citrate Synthase From E. Coli | Descriptor: | Citrate synthase, SULFATE ION | Authors: | Stokell, D.J, Donald, L.J, Maurus, R, Nguyen, N.T, Sadler, G, Choudhary, K, Hultin, P.G, Brayer, G.D, Duckworth, H.W. | Deposit date: | 2003-03-28 | Release date: | 2004-05-18 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Probing the roles of key residues in the unique regulatory NADH binding site of type II citrate synthase of Escherichia coli. J.Biol.Chem., 278, 2003
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1OWB
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![BU of 1owb by Molmil](/molmil-images/mine/1owb) | Three Dimensional Structure Analysis Of The Variant R109L NADH Complex of Type II Citrate Synthase From E. Coli | Descriptor: | Citrate synthase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION | Authors: | Stokell, D.J, Donald, L.J, Maurus, R, Nguyen, N.T, Sadler, G, Choudhary, K, Hultin, P.G, Brayer, G.D, Duckworth, H.W. | Deposit date: | 2003-03-28 | Release date: | 2004-05-18 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Probing the roles of key residues in the unique regulatory NADH binding site of type II citrate synthase of Escherichia coli. J.Biol.Chem., 278, 2003
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1OVG
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![BU of 1ovg by Molmil](/molmil-images/mine/1ovg) | M64V PNP +MePdr | Descriptor: | 9-(2-DEOXY-BETA-D-RIBOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase | Authors: | Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, P.W, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J. | Deposit date: | 2003-03-26 | Release date: | 2004-02-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system. Chem.Biol., 10, 2003
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1OQA
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![BU of 1oqa by Molmil](/molmil-images/mine/1oqa) | Solution structure of the BRCT-c domain from human BRCA1 | Descriptor: | Breast cancer type 1 susceptibility protein | Authors: | Gaiser, O.J, Ball, L.J, Schmieder, P, Leitner, D, Strauss, H, Wahl, M, Kuhne, R, Oschkinat, H, Heinemann, U. | Deposit date: | 2003-03-07 | Release date: | 2004-06-15 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure, backbone dynamics, and association behavior of the C-terminal BRCT domain from the breast cancer-associated protein BRCA1. Biochemistry, 43, 2004
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1OU4
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![BU of 1ou4 by Molmil](/molmil-images/mine/1ou4) | Native PNP +Talo | Descriptor: | 6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase | Authors: | Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, W.B, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J. | Deposit date: | 2003-03-24 | Release date: | 2004-02-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system. Chem.Biol., 10, 2003
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1OYN
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![BU of 1oyn by Molmil](/molmil-images/mine/1oyn) | Crystal structure of PDE4D2 in complex with (R,S)-rolipram | Descriptor: | ROLIPRAM, ZINC ION, cAMP-specific phosphodiesterase PDE4D2 | Authors: | Huai, Q, Wang, H, Sun, Y, Kim, H.Y, Liu, Y, Ke, H. | Deposit date: | 2003-04-05 | Release date: | 2003-07-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Three-dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity Structure, 11, 2003
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1OP4
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![BU of 1op4 by Molmil](/molmil-images/mine/1op4) | Solution Structure of Neural Cadherin Prodomain | Descriptor: | Neural-cadherin | Authors: | Koch, A.W, Farooq, A, Shan, W, Zeng, L, Colman, D.R, Zhou, M.-M. | Deposit date: | 2003-03-04 | Release date: | 2004-03-16 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Structure of the Neural (N-) Cadherin Prodomain Reveals a Cadherin Extracellular Domain-like Fold without Adhesive Characteristics Structure, 12, 2004
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1OTX
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![BU of 1otx by Molmil](/molmil-images/mine/1otx) | Purine Nucleoside Phosphorylase M64V mutant | Descriptor: | PHOSPHATE ION, Purine nucleoside phosphorylase | Authors: | Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, W.B, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J. | Deposit date: | 2003-03-23 | Release date: | 2004-02-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system. Chem.Biol., 10, 2003
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1OQN
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![BU of 1oqn by Molmil](/molmil-images/mine/1oqn) | Crystal structure of the phosphotyrosine binding domain (PTB) of mouse Disabled 1 (Dab1) | Descriptor: | Alzheimer's disease amyloid A4 protein homolog, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Disabled homolog 1 | Authors: | Yun, M, Keshvara, L, Park, C.-G, Zhang, Y.-M, Dickerson, J.B, Zheng, J, Rock, C.O, Curran, T, Park, H.-W. | Deposit date: | 2003-03-10 | Release date: | 2003-08-05 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of the Dab homology domains of mouse disabled 1 and 2 J.Biol.Chem., 278, 2003
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1OTY
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![BU of 1oty by Molmil](/molmil-images/mine/1oty) | Native PNP +ALLO | Descriptor: | 6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase | Authors: | Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, W.B, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J. | Deposit date: | 2003-03-23 | Release date: | 2004-02-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system. Chem.Biol., 10, 2003
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1P4R
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![BU of 1p4r by Molmil](/molmil-images/mine/1p4r) | Crystal Structure of Human ATIC in complex with folate-based inhibitor BW1540U88UD | Descriptor: | AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, Bifunctional purine biosynthesis protein PURH, N-[(S)-(4-{[(2-AMINO-4-HYDROXYQUINAZOLIN-6-YL)(DIHYDROXY)-LAMBDA~4~-SULFANYL]AMINO}PHENYL)(HYDROXY)METHYL]-L-GLUTAMIC ACID, ... | Authors: | Cheong, C.-G, Greasley, S.E, Horton, P.A, Beardsley, G.P, Wilson, I.A. | Deposit date: | 2003-04-23 | Release date: | 2004-03-30 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates J.Biol.Chem., 279, 2004
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1PCE
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![BU of 1pce by Molmil](/molmil-images/mine/1pce) | SOLUTION STRUCTURE AND DYNAMICS OF PEC-60, A PROTEIN OF THE KAZAL TYPE INHIBITOR FAMILY, DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY | Descriptor: | PEC-60 | Authors: | Liepinsh, E, Berndt, K.D, Sillard, R, Mutt, V, Otting, G. | Deposit date: | 1994-02-22 | Release date: | 1994-04-30 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Solution structure and dynamics of PEC-60, a protein of the Kazal type inhibitor family, determined by nuclear magnetic resonance spectroscopy. J.Mol.Biol., 239, 1994
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1PD9
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![BU of 1pd9 by Molmil](/molmil-images/mine/1pd9) | Analysis of Three Crystal Structure Determinations of a 5-Methyl-6-N-Methylanilino Pyridopyrimidine antifolate Complex with Human Dihydrofolate Reductase | Descriptor: | 2,4-DIAMINO-5-METHYL-6-[(3,4,5-TRIMETHOXY-N-METHYLANILINO)METHYL]PYRIDO[2,3-D]PYRIMIDINE, Dihydrofolate reductase, SULFATE ION | Authors: | Cody, V, Luft, J.R, Pangborn, W, Gangjee, A. | Deposit date: | 2003-05-19 | Release date: | 2003-12-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Analysis of three crystal structure determinations of a 5-methyl-6-N-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase. Acta Crystallogr.,Sect.D, 59, 2003
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1PD8
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![BU of 1pd8 by Molmil](/molmil-images/mine/1pd8) | Analysis of Three Crystal Structure Determinations of a 5-Methyl-6-N-Methylanilino Pyridopyrimidine Antifolate Complex with Human Dihydrofolate Reductase | Descriptor: | 2,4-DIAMINO-5-METHYL-6-[(3,4,5-TRIMETHOXY-N-METHYLANILINO)METHYL]PYRIDO[2,3-D]PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Cody, V, Luft, J.R, Pangborn, W, Gangjee, A. | Deposit date: | 2003-05-19 | Release date: | 2003-12-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Analysis of three crystal structure determinations of a 5-methyl-6-N-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase. Acta Crystallogr.,Sect.D, 59, 2003
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1PDB
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![BU of 1pdb by Molmil](/molmil-images/mine/1pdb) | Analysis of Three Crystal Structure Determinations of a 5-Methyl-6-N-Methylanilino Pyridopyrimidine Antifolate Complex with Human Dihydrofolate Reductase | Descriptor: | Dihydrofolate reductase | Authors: | Cody, V, Luft, J.R, Pangborn, W, Gangjee, A. | Deposit date: | 2003-05-19 | Release date: | 2003-12-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Analysis of three crystal structure determinations of a 5-methyl-6-N-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase. Acta Crystallogr.,Sect.D, 59, 2003
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1PDG
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![BU of 1pdg by Molmil](/molmil-images/mine/1pdg) | CRYSTAL STRUCTURE OF HUMAN PLATELET-DERIVED GROWTH FACTOR BB | Descriptor: | PLATELET-DERIVED GROWTH FACTOR BB | Authors: | Oefner, C, Darcy, A.D, Winkler, F.K, Eggimann, B, Hosnag, M. | Deposit date: | 1992-07-14 | Release date: | 1994-01-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of human platelet-derived growth factor BB. EMBO J., 11, 1992
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1PCP
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![BU of 1pcp by Molmil](/molmil-images/mine/1pcp) | SOLUTION STRUCTURE OF A TREFOIL-MOTIF-CONTAINING CELL GROWTH FACTOR, PORCINE SPASMOLYTIC PROTEIN | Descriptor: | PORCINE SPASMOLYTIC PROTEIN | Authors: | Carr, M.D, Bauer, C.J, Gradwell, M.J, Feeney, J. | Deposit date: | 1993-02-04 | Release date: | 1994-05-31 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Solution structure of a trefoil-motif-containing cell growth factor, porcine spasmolytic protein. Proc.Natl.Acad.Sci.USA, 91, 1994
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1PBU
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![BU of 1pbu by Molmil](/molmil-images/mine/1pbu) | Solution structure of the C-terminal domain of the human eEF1Bgamma subunit | Descriptor: | Elongation factor 1-gamma | Authors: | Vanwetswinkel, S, Kriek, J, Andersen, G.R, Guntert, P, Dijk, J, Canters, G.W, Siegal, G. | Deposit date: | 2003-05-15 | Release date: | 2003-07-15 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | 1H, (15)N and (13)C resonance assignments of the highly conserved 19 kDa C-terminal domain from human Elongation Factor 1Bgamma. J.Biomol.Nmr, 26, 2003
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1PJM
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![BU of 1pjm by Molmil](/molmil-images/mine/1pjm) | Mouse Importin alpha-bipartite NLS from human retinoblastoma protein Complex | Descriptor: | Importin alpha-2 subunit, Retinoblastoma-associated protein | Authors: | Fontes, M.R.M, Teh, T, Jans, D, Brinkworth, R.I, Kobe, B. | Deposit date: | 2003-06-03 | Release date: | 2003-08-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha J.Biol.Chem., 278, 2003
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3R9L
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![BU of 3r9l by Molmil](/molmil-images/mine/3r9l) | |
3SLD
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![BU of 3sld by Molmil](/molmil-images/mine/3sld) | Structural characterization of a GII.4 2004 norovirus variant (TCH05) bound to A trisaccharide | Descriptor: | Capsid, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose | Authors: | Shanker, S, Choi, J.-M, Sankaran, B, Atmar, R.L, Estes, M.K, Prasad, B.V.V. | Deposit date: | 2011-06-24 | Release date: | 2011-07-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.679 Å) | Cite: | Structural Analysis of Histo-Blood Group Antigen Binding Specificity in a Norovirus GII.4 Epidemic Variant: Implications for Epochal Evolution. J.Virol., 85, 2011
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1PL4
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![BU of 1pl4 by Molmil](/molmil-images/mine/1pl4) | Crystal Structure of human MnSOD Y166F mutant | Descriptor: | MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial | Authors: | Fan, L, Tainer, J.A. | Deposit date: | 2003-06-06 | Release date: | 2003-12-16 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Amino acid substitution at the dimeric interface of human manganese superoxide dismutase J.Biol.Chem., 279, 2004
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1PKG
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![BU of 1pkg by Molmil](/molmil-images/mine/1pkg) | Structure of a c-Kit Kinase Product Complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, c-kit protein | Authors: | Mol, C.D, Lim, K.B, Sridhar, V, Zou, H, Chien, E.Y.T, Sang, B.-C, Nowakowski, J, Kassel, D.B, Cronin, C.N, McRee, D.E. | Deposit date: | 2003-06-05 | Release date: | 2003-08-12 | Last modified: | 2017-08-09 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of a c-Kit Product Complex Reveals the Basis for Kinase Transactivation. J.Biol.Chem., 278, 2003
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1PX5
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![BU of 1px5 by Molmil](/molmil-images/mine/1px5) | Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase | Descriptor: | 2'-5'-oligoadenylate synthetase 1, SULFATE ION | Authors: | Hartmann, R, Justesen, J, Sarkar, S.N, Sen, G.C, Yee, V.C. | Deposit date: | 2003-07-02 | Release date: | 2003-11-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase Mol.Cell, 12, 2003
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