1OTX

Purine Nucleoside Phosphorylase M64V mutant

Summary for 1OTX

Related1ECP 1A90 1OTY
DescriptorPurine nucleoside phosphorylase, PHOSPHATE ION (3 entities in total)
Functional Keywordsempty, pnp, transferase
Biological sourceEscherichia coli
Total number of polymer chains3
Total molecular weight77740.97
Authors
Ealick, S.E.,Bennett, E.M.,Anand, R.,Secrist, J.A.,Parker, W.B.,Hassan, A.E.,Allan, P.W.,McPherson, D.T.,Sorscher, E.J. (deposition date: 2003-03-23, release date: 2004-02-17, Last modification date: 2011-07-13)
Primary citation
Bennett, E.M.,Anand, R.,Allan, P.W.,Hassan, A.E.,Hong, J.S.,Levasseur, D.N.,McPherson, D.T.,Parker, W.B.,Secrist, J.A.,Sorscher, E.J.,Townes, T.M.,Waud, W.R.,Ealick, S.E.
Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10:1173-1181, 2003
PubMed: 14700625 (PDB entries with the same primary citation)
DOI: 10.1016/j.chembiol.2003.11.008
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.24515 0.3% 3.2% 6.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171588
PDB entries from 2020-11-25