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1P6A
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BU of 1p6a by Molmil
STRUCTURAL BASIS FOR VARIATION IN ADENOVIRUS AFFINITY FOR THE CELLULAR RECEPTOR CAR (S489Y MUTANT)
Descriptor: Coxsackievirus and adenovirus receptor, Fiber protein
Authors:Howitt, J, Bewley, M.C, Graziano, V, Flanagan, J.M, Freimuth, P.
Deposit date:2003-04-29
Release date:2004-05-11
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for variation in adenovirus affinity for the cellular coxsackievirus and adenovirus receptor.
J.Biol.Chem., 278, 2003
1OT8
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BU of 1ot8 by Molmil
Structure of the Ankyrin Domain of the Drosophila Notch Receptor
Descriptor: MAGNESIUM ION, Neurogenic locus Notch protein
Authors:Zweifel, M.E, Leahy, D.J, Hughson, F.M, Barrick, D.
Deposit date:2003-03-21
Release date:2003-10-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and stability of the ankyrin domain of the Drosophila Notch receptor
Protein Sci., 12, 2003
3PD1
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BU of 3pd1 by Molmil
Caspase-3 K242A
Descriptor: Caspase-3, Inhibitor Ac-DEVD-CMK
Authors:Walters, J, Swartz, P, Mattos, C, Clark, A.C.
Deposit date:2010-10-22
Release date:2011-02-23
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3.
Arch.Biochem.Biophys., 508, 2011
2OAX
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BU of 2oax by Molmil
Crystal structure of the S810L mutant mineralocorticoid receptor associated with SC9420
Descriptor: Mineralocorticoid receptor, SPIRONOLACTONE
Authors:Huyet, J, Pinon, G.M, Fay, M.R, Rafestin-Oblin, M.E, Fagart, J.
Deposit date:2006-12-18
Release date:2007-08-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structural basis of spirolactone recognition by the mineralocorticoid receptor
Mol.Pharmacol., 72, 2007
4EMQ
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BU of 4emq by Molmil
Crystal structure of a single mutant of Dronpa, the green-on-state PDM1-4
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, Fluorescent protein Dronpa, ...
Authors:Ngan, N.B, Van Hecke, K, Van Meervelt, L.
Deposit date:2012-04-12
Release date:2012-11-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis for the influence of a single mutation K145N on the oligomerization and photoswitching rate of Dronpa.
Acta Crystallogr.,Sect.D, 68, 2012
3PD0
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BU of 3pd0 by Molmil
Caspase-3 E246A
Descriptor: CHLORIDE ION, Caspase-3, INHIBITOR AC-DEVD-CMK
Authors:Walters, J, Swartz, P, Mattos, C, Clark, A.C.
Deposit date:2010-10-22
Release date:2011-02-16
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3.
Arch.Biochem.Biophys., 508, 2011
3RUP
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BU of 3rup by Molmil
Crystal structure of E.coli biotin carboxylase in complex with two ADP and two Ca ions
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, CALCIUM ION, ...
Authors:Chou, C.Y, Tong, L.
Deposit date:2011-05-05
Release date:2011-05-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization.
J.Biol.Chem., 286, 2011
3RV4
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BU of 3rv4 by Molmil
Crystal structure of E.coli biotin carboxylase R16E mutant in complex with Mg-ADP and bicarbonate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BICARBONATE ION, Biotin carboxylase, ...
Authors:Chou, C.Y, Tong, L.
Deposit date:2011-05-05
Release date:2011-05-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization.
J.Biol.Chem., 286, 2011
4NBL
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BU of 4nbl by Molmil
Tailoring Small Molecules for an Allosteric Site on Procaspase-6
Descriptor: 5-fluoro-2-({[3-(pyrimidin-2-yl)pyridin-2-yl]amino}methyl)phenol, Caspase-6, PHOSPHATE ION
Authors:Murray, J.M, Steffek, M.
Deposit date:2013-10-23
Release date:2014-01-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.756 Å)
Cite:Tailoring small molecules for an allosteric site on procaspase-6.
Chemmedchem, 9, 2014
6BOE
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BU of 6boe by Molmil
TBK1 in complex with amide-coupled tetrazole analog of amlexanox
Descriptor: 2-amino-5-oxo-7-(propan-2-yl)-N-(1H-tetrazol-5-yl)-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxamide, Serine/threonine-protein kinase TBK1
Authors:Beyett, T.S, Tesmer, J.J.G.
Deposit date:2017-11-19
Release date:2018-09-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.598 Å)
Cite:Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKepsilonand Reveal Mechanisms for Selective Inhibition.
Mol. Pharmacol., 94, 2018
4BNC
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BU of 4bnc by Molmil
Crystal structure of the DNA-binding domain of human ETV1 complexed with DNA
Descriptor: 5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP)-3', 5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP)-3', HUMAN ETV1
Authors:Allerston, C.K, Cooper, C.D.O, Krojer, T, Chaikuad, A, Vollmar, M, Froese, D.S, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Gileadi, O.
Deposit date:2013-05-14
Release date:2013-07-03
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation.
J.Biol.Chem., 290, 2015
4N7M
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BU of 4n7m by Molmil
Tailoring Small Molecules for an Allosteric Site on Procaspase-6
Descriptor: 3-(pyrrolidin-1-yl)isoquinolin-1(2H)-one, Caspase-6, PHOSPHATE ION
Authors:Murray, J.M, Steffek, M.
Deposit date:2013-10-15
Release date:2013-12-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.125 Å)
Cite:Tailoring small molecules for an allosteric site on procaspase-6.
Chemmedchem, 9, 2014
4N6G
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BU of 4n6g by Molmil
Tailoring Small Molecules for an Allosteric Site on Procaspase-6
Descriptor: 3-(pyrrolidin-1-yl)isoquinolin-1(2H)-one, Caspase-6, PHOSPHATE ION
Authors:Murray, J.M, Steffek, M.
Deposit date:2013-10-11
Release date:2014-01-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.142 Å)
Cite:Tailoring small molecules for an allosteric site on procaspase-6.
Chemmedchem, 9, 2014
4NBM
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BU of 4nbm by Molmil
Crystal structure of UVB photoreceptor UVR8 and light-induced structural changes at 180K
Descriptor: MAGNESIUM ION, Ultraviolet-B receptor UVR8
Authors:Yang, X, Zeng, X, Zhao, K.-H, Ren, Z.
Deposit date:2013-10-23
Release date:2016-10-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Dynamic Crystallography Reveals Early Signalling Events in Ultraviolet Photoreceptor UVR8.
Nat Plants, 1, 2015
4NBK
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BU of 4nbk by Molmil
Tailoring Small Molecules for an Allosteric Site on Procaspase-6
Descriptor: 2-{[(3-methylpyridin-2-yl)amino]methyl}phenol, Caspase-6, PHOSPHATE ION
Authors:Murray, J.M, Steffek, M.
Deposit date:2013-10-23
Release date:2014-01-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.936 Å)
Cite:Tailoring small molecules for an allosteric site on procaspase-6.
Chemmedchem, 9, 2014
1O95
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BU of 1o95 by Molmil
Ternary complex between trimethylamine dehydrogenase and electron transferring flavoprotein
Descriptor: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ELECTRON TRANSFER FLAVOPROTEIN ALPHA-SUBUNIT, ...
Authors:Leys, D, Basran, J, Talfournier, F, Sutcliffe, M.J, Scrutton, N.S.
Deposit date:2002-12-11
Release date:2003-02-06
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Extensive Conformational Sampling in a Ternary Electron Transfer Complex.
Nat.Struct.Biol., 10, 2003
6BOD
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BU of 6bod by Molmil
TBK1 in complex with ethyl ester analog of amlexanox
Descriptor: Serine/threonine-protein kinase TBK1, ethyl 2-amino-5-oxo-7-(propan-2-yl)-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylate
Authors:Beyett, T.S, Tesmer, J.J.G.
Deposit date:2017-11-19
Release date:2018-09-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.197 Å)
Cite:Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKepsilonand Reveal Mechanisms for Selective Inhibition.
Mol. Pharmacol., 94, 2018
3OF6
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BU of 3of6 by Molmil
Human pre-T cell receptor crystal structure
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Pre T-cell antigen receptor alpha, T cell receptor beta chain
Authors:Pang, S.S.
Deposit date:2010-08-13
Release date:2010-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structural basis for autonomous dimerization of the pre-T-cell antigen receptor
Nature, 467, 2010
3TNF
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BU of 3tnf by Molmil
LidA from Legionella in complex with active Rab8a
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, LidA, MAGNESIUM ION, ...
Authors:Schoebel, S, Cichy, A.L, Goody, R.S, Itzen, A.
Deposit date:2011-09-01
Release date:2011-11-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Protein LidA from Legionella is a Rab GTPase supereffector.
Proc.Natl.Acad.Sci.USA, 108, 2011
4N7J
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BU of 4n7j by Molmil
Tailoring Small Molecules for an Allosteric Site on Procaspase-6
Descriptor: 3-(pyrrolidin-1-yl)isoquinolin-1(2H)-one, Caspase-6, PHOSPHATE ION
Authors:Murray, J.M, Steffek, M.
Deposit date:2013-10-15
Release date:2013-12-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.673 Å)
Cite:Tailoring small molecules for an allosteric site on procaspase-6.
Chemmedchem, 9, 2014
1O97
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BU of 1o97 by Molmil
Structure of electron transferring flavoprotein from Methylophilus methylotrophus, recognition loop removed by limited proteolysis
Descriptor: ADENOSINE MONOPHOSPHATE, ELECTRON TRANSFERRING FLAVOPROTEIN ALPHA-SUBUNIT, ELECTRON TRANSFERRING FLAVOPROTEIN BETA-SUBUNIT, ...
Authors:Leys, D, Basran, J, Talfournier, F, Sutcliffe, M.J, Scrutton, N.S.
Deposit date:2002-12-11
Release date:2003-02-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Extensive Conformational Sampling in a Ternary Electron Transfer Complex.
Nat.Struct.Biol., 10, 2003
3BT7
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BU of 3bt7 by Molmil
Structure of E. coli 5-Methyluridine Methyltransferase TrmA in complex with 19 nucleotide T-arm analogue
Descriptor: RNA (5'-D(P*GP*CP*UP*GP*UP*GP*(5MU)P*UP*CP*GP*AP*UP*CP*CP*AP*CP*AP*GP*C)-3'), tRNA (uracil-5-)-methyltransferase
Authors:Alian, A, Stroud, R.M, Finer-Moore, J.
Deposit date:2007-12-27
Release date:2008-04-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structure of a TrmA-RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m5U methyltransferases.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1NZI
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BU of 1nzi by Molmil
Crystal Structure of the CUB1-EGF Interaction Domain of Complement Protease C1s
Descriptor: CALCIUM ION, Complement C1s component, MAGNESIUM ION
Authors:Gregory, L.A, Thielens, N.M, Arlaud, G.J, Fontecilla-Camps, J.C, Gaboriaud, C.
Deposit date:2003-02-18
Release date:2003-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:X-ray structure of the Ca2+-binding interaction domain of C1s. Insights into the assembly of the C1 complex of complement
J.Biol.Chem., 278, 2003
1O96
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BU of 1o96 by Molmil
Structure of electron transferring flavoprotein for Methylophilus methylotrophus.
Descriptor: ADENOSINE MONOPHOSPHATE, ELECTRON TRANSFERRING FLAVOPROTEIN ALPHA-SUBUNIT, ELECTRON TRANSFERRING FLAVOPROTEIN BETA-SUBUNIT, ...
Authors:Leys, D, Basran, J, Talfournier, F, Sutcliffe, M.J, Scrutton, N.S.
Deposit date:2002-12-11
Release date:2003-02-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Extensive Conformational Sampling in a Ternary Electron Transfer Complex.
Nat.Struct.Biol., 10, 2003
1NFP
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BU of 1nfp by Molmil
STRUCTURAL REFINEMENT OF THE NON-FLUORESCENT FLAVOPROTEIN FROM PHOTOBACTERIUM LEIOGNATHI AT 1.60 ANGSTROMS RESOLUTION
Descriptor: FLAVIN MONONUCLEOTIDE, LUXF GENE PRODUCT, MYRISTIC ACID, ...
Authors:Moore, S.A, Njames, M.N.G.
Deposit date:1995-02-27
Release date:1995-06-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural refinement of the non-fluorescent flavoprotein from Photobacterium leiognathi at 1.60 A resolution.
J.Mol.Biol., 249, 1995

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