4BNC

Crystal structure of the DNA-binding domain of human ETV1 complexed with DNA

Replaces:  4B06

Summary for 4BNC

• Entry DOI: 10.2210/pdb4bnc/pdb
• Descriptor: HUMAN ETV1, 5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP)-3', 5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP)-3' (3 entities in total)
• Functional Keywords: dna-binding protein, dna binding protein
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Nucleus : P50549
• Total number of polymer chains: 3
• Total formula weight: 18527.22

Authors

Allerston, C.K.,Cooper, C.D.O.,Krojer, T.,Chaikuad, A.,Vollmar, M.,Froese, D.S.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,von Delft, F.,Gileadi, O. (deposition date: 2013-05-14, release date: 2013-07-03, Last modification date: 2015-06-10)

• Primary citation: Cooper, C.D.O.,Newman, J.A.,Aitkenhead, H.,Allerston, C.K.,Gileadi, O.; Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation.; J.Biol.Chem., 290:13692-, 2015; PubMed: 25866208; DOI: 10.1074/JBC.M115.646737

Experimental method

X-RAY DIFFRACTION (2.9 Å)