3BT7

Structure of E. coli 5-Methyluridine Methyltransferase TrmA in complex with 19 nucleotide T-arm analogue

Summary for 3BT7

• Entry DOI: 10.2210/pdb3bt7/pdb
• Related: 1uwv 2BH2
• Descriptor: tRNA (uracil-5-)-methyltransferase, RNA (5'-D(P*GP*CP*UP*GP*UP*GP*(5MU)P*UP*CP*GP*AP*UP*CP*CP*AP*CP*AP*GP*C)-3') (3 entities in total)
• Functional Keywords: methyluridine, methyltransferase, trma, rumt, s-adenosyl-l-methionine, trna processing, transferase-rna complex, transferase/rna
• Biological source: Escherichia coli; More
• Total number of polymer chains: 4
• Total formula weight: 96685.55

Authors

Alian, A.,Stroud, R.M.,Finer-Moore, J. (deposition date: 2007-12-27, release date: 2008-04-29, Last modification date: 2023-08-30)

• Primary citation: Alian, A.,Lee, T.T.,Griner, S.L.,Stroud, R.M.,Finer-Moore, J.; Structure of a TrmA-RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m5U methyltransferases.; Proc.Natl.Acad.Sci.Usa, 105:6876-6881, 2008; PubMed: 18451029; DOI: 10.1073/pnas.0802247105

Experimental method

X-RAY DIFFRACTION (2.43 Å)