3PD0
Caspase-3 E246A
Summary for 3PD0
Entry DOI | 10.2210/pdb3pd0/pdb |
Related | 3PCX 3PD1 |
Related PRD ID | PRD_000238 |
Descriptor | Caspase-3, INHIBITOR AC-DEVD-CMK, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | salt bridge, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P42574 |
Total number of polymer chains | 2 |
Total formula weight | 29166.97 |
Authors | Walters, J.,Swartz, P.,Mattos, C.,Clark, A.C. (deposition date: 2010-10-22, release date: 2011-02-16, Last modification date: 2012-12-12) |
Primary citation | Walters, J.,Swartz, P.,Mattos, C.,Clark, A.C. Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3. Arch.Biochem.Biophys., 508:31-38, 2011 Cited by PubMed: 21266160DOI: 10.1016/j.abb.2011.01.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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