2RN2
| STRUCTURAL DETAILS OF RIBONUCLEASE H FROM ESCHERICHIA COLI AS REFINED TO AN ATOMIC RESOLUTION | Descriptor: | RIBONUCLEASE H | Authors: | Katayanagi, K, Miyagawa, M, Matsushima, M, Ishikawa, M, Kanaya, S, Nakamura, H, Ikehara, M, Matsuzaki, T, Morikawa, K. | Deposit date: | 1992-04-15 | Release date: | 1993-10-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Structural details of ribonuclease H from Escherichia coli as refined to an atomic resolution. J.Mol.Biol., 223, 1992
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2RN7
| NMR solution structure of TnpE protein from Shigella flexneri. Northeast Structural Genomics Target SfR125 | Descriptor: | IS629 orfA | Authors: | Ramelot, T.A, Cort, J.R, Semesi, A, Garcia, M, Yee, A.A, Arrowsmith, C.H, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-12-08 | Release date: | 2008-01-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR solution structure of TnpE protein from Shigella flexneri. Northeast
Structural Genomics Target SfR125 To be Published
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2RNZ
| Solution structure of the presumed chromodomain of the yeast histone acetyltransferase, Esa1 | Descriptor: | Histone acetyltransferase ESA1 | Authors: | Shimojo, H, Sano, N, Moriwaki, Y, Okuda, M, Horikoshi, M, Nishimura, Y. | Deposit date: | 2008-03-01 | Release date: | 2008-04-29 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Novel structural and functional mode of a knot essential for RNA binding activity of the Esa1 presumed chromodomain J.Mol.Biol., 378, 2008
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2RK6
| Structure of E163K DJ-1 | Descriptor: | Protein DJ-1 | Authors: | Lakshminarasimhan, M, Maldonado, M.T, Zhou, W, Fink, A.L, Wilson, M.A. | Deposit date: | 2007-10-16 | Release date: | 2008-01-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Structural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1. Biochemistry, 47, 2008
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2ROE
| Solution structure of thermus thermophilus HB8 TTHA1718 protein in vitro | Descriptor: | Heavy metal binding protein | Authors: | Sakakibara, D, Sasaki, A, Ikeya, T, Hamatsu, J, Koyama, H, Mishima, M, Mikawa, T, Waelchli, M, Smith, B.O, Shirakawa, M, Guentert, P, Ito, Y. | Deposit date: | 2008-03-20 | Release date: | 2009-03-03 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Protein structure determination in living cells by in-cell NMR spectroscopy Nature, 458, 2009
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2ROW
| The C1 domain of ROCK II | Descriptor: | Rho-associated protein kinase 2, ZINC ION | Authors: | Wen, W, Zhang, M. | Deposit date: | 2008-04-25 | Release date: | 2008-06-24 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The C1 domain of ROCK II To be Published
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2RPC
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1IRY
| Solution structure of the hMTH1, a nucleotide pool sanitization enzyme | Descriptor: | hMTH1 | Authors: | Mishima, M, Itoh, N, Sakai, Y, Kamiya, H, Nakabeppu, Y, Shirakawa, M. | Deposit date: | 2001-10-25 | Release date: | 2003-12-23 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structure of human MTH1, a Nudix family hydrolase that selectively degrades oxidized purine nucleoside triphosphates J.Biol.Chem., 279, 2004
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8GXP
| Complex structure of RORgama with betulinic acid | Descriptor: | Betulinic acid, Nuclear receptor ROR-gamma | Authors: | Zhang, X.L, Xu, C, Bai, F. | Deposit date: | 2022-09-20 | Release date: | 2023-06-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR gamma antagonists. Eur.J.Med.Chem., 257, 2023
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1IQX
| CRYSTAL STRUCTURE OF COBALT-SUBSTITUTED AMINE OXIDASE FROM ARTHROBACTER GLOBIFORMIS | Descriptor: | CO(II)-SUBSTITUTED AMINE OXIDASE, COBALT (II) ION | Authors: | Kishishita, S, Okajima, T, Mure, M, Kim, M, Yamaguchi, H, Hirota, S, Suzuki, S, Kuroda, S, Tanizawa, K. | Deposit date: | 2001-08-27 | Release date: | 2003-02-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Role of Copper Ion in Bacterial Copper Amine Oxidase: Spectroscopic and Crystallographic Studies of Metal-Substituted Enzymes J.AM.CHEM.SOC., 125, 2003
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2RLP
| NMR structure of CCP modules 1-2 of complement factor H | Descriptor: | Complement factor H | Authors: | Hocking, H.G, Herbert, A.P, Pangburn, M.K, Kavanagh, D, Barlow, P.N, Uhrin, D. | Deposit date: | 2007-07-28 | Release date: | 2008-02-19 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations. J.Biol.Chem., 283, 2008
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2RMW
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6JVN
| Crystal structure of human MTH1 in complex with compound MI1020 | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, N4-methyl-6-morpholin-4-yl-pyrimidine-2,4-diamine | Authors: | Peng, C, Li, Y.H, Cheng, Y.S. | Deposit date: | 2019-04-17 | Release date: | 2020-10-28 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.102 Å) | Cite: | Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity. Bioorg.Chem., 110, 2021
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6JVX
| Crystal structure of RBM38 in complex with RNA | Descriptor: | RNA (5'-R(*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*G)-3'), RNA-binding protein 38, SULFATE ION | Authors: | Qian, K, Li, M, Wang, J, Zhang, M, Wang, M. | Deposit date: | 2019-04-17 | Release date: | 2020-01-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Structural basis for mRNA recognition by human RBM38. Biochem.J., 477, 2020
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2SGF
| PHE 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B | Descriptor: | Ovomucoid, PHOSPHATE ION, Streptogrisin B | Authors: | Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G. | Deposit date: | 1999-03-25 | Release date: | 2003-08-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pHs To be Published
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2SIL
| THE STRUCTURES OF SALMONELLA TYPHIMURIUM LT2 NEURAMINIDASE AND ITS COMPLEX WITH A TRANSITION STATE ANALOGUE AT 1.6 ANGSTROMS RESOLUTION | Descriptor: | SIALIDASE | Authors: | Taylor, G.L, Crennell, S.J, Garman, E.F, Vimr, E.R, Laver, W.G. | Deposit date: | 1994-07-13 | Release date: | 1994-08-31 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The structures of Salmonella typhimurium LT2 neuraminidase and its complexes with three inhibitors at high resolution. J.Mol.Biol., 259, 1996
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2RNF
| X-RAY CRYSTAL STRUCTURE OF HUMAN RIBONUCLEASE 4 IN COMPLEX WITH D(UP) | Descriptor: | 2'-DEOXYURIDINE 3'-MONOPHOSPHATE, RIBONUCLEASE 4 | Authors: | Terzyan, S.S, Peracaula, R, De Llorens, R, Tsushima, Y, Yamada, H, Seno, M, Gomis-Ruth, F.X, Coll, M. | Deposit date: | 1998-11-03 | Release date: | 1999-11-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The three-dimensional structure of human RNase 4, unliganded and complexed with d(Up), reveals the basis for its uridine selectivity. J.Mol.Biol., 285, 1999
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6JSX
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2RNL
| Solution structure of the EGF-like domain from human Amphiregulin | Descriptor: | Amphiregulin | Authors: | Qin, X, Hayashi, F, Terada, T, Shirouzu, M, Watanabe, S, Kigawa, T, Yabuta, N, Nojima, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2008-01-11 | Release date: | 2009-01-20 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Solution structure of the EGF-like domain from human Amphiregulin To be Published
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8HBM
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8H0R
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2SNS
| STAPHYLOCOCCAL NUCLEASE. PROPOSED MECHANISM OF ACTION BASED ON STRUCTURE OF ENZYME-THYMIDINE 3(PRIME),5(PRIME)-BIPHOSPHATE-CALCIUM ION COMPLEX AT 1.5-ANGSTROMS RESOLUTION | Descriptor: | CALCIUM ION, THERMONUCLEASE PRECURSOR, THYMIDINE-3',5'-DIPHOSPHATE | Authors: | Legg, M.J, Cotton, F.A, Hazen Jr, E.E. | Deposit date: | 1982-05-14 | Release date: | 1982-07-29 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Thesis, Texas Agricultural and Mechanical University, 1977
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2SPC
| CRYSTAL STRUCTURE OF THE REPETITIVE SEGMENTS OF SPECTRIN | Descriptor: | SPECTRIN | Authors: | Yan, Y, Winograd, E, Viel, A, Cronin, T, Harrison, S.C, Branton, D. | Deposit date: | 1994-03-01 | Release date: | 1994-05-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the repetitive segments of spectrin. Science, 262, 1993
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2RTO
| STREPTAVIDIN-2-IMINOBIOTIN COMPLEX, PH 2.6, SPACE GROUP I222 | Descriptor: | 2-IMINOBIOTIN, STREPTAVIDIN | Authors: | Katz, B.A. | Deposit date: | 1997-09-11 | Release date: | 1998-10-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH. J.Mol.Biol., 274, 1997
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2RNX
| The Structural Basis for Site-Specific Lysine-Acetylated Histone Recognition by the Bromodomains of the HUman Transcriptional Co-Activators PCAF and CBP | Descriptor: | Histone H3, Histone acetyltransferase PCAF | Authors: | Zeng, L, Zhang, Q, Gerona-Navarro, G, Zhou, M.M. | Deposit date: | 2008-02-03 | Release date: | 2008-05-06 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300 Structure, 16, 2008
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