8H0R

Crystal structure of a cataract-causing crystallin mutant (mouse CRYBB1 Y202X)

Summary for 8H0R

• Entry DOI: 10.2210/pdb8h0r/pdb
• Descriptor: Beta-crystallin B1B (2 entities in total)
• Functional Keywords: crystallin crybb1, trancated mutant, structural protein
• Biological source: Mus musculus (house mouse)
• Total number of polymer chains: 2
• Total formula weight: 21518.23

Authors

Jing, X.,Gong, P. (deposition date: 2022-09-30, release date: 2023-07-05, Last modification date: 2023-08-16)

• Primary citation: Jing, X.,Zhu, M.,Lu, X.,Wei, P.,Shi, L.,Zhang, B.Y.,Xu, Y.,Tang, Y.P.,Xiang, D.M.,Gong, P.; Cataract-causing Y204X mutation of crystallin protein CRY beta B1 promotes its C-terminal degradation and higher-order oligomerization.; J.Biol.Chem., 299:104953-104953, 2023; PubMed: 37356717; DOI: 10.1016/j.jbc.2023.104953

Experimental method

X-RAY DIFFRACTION (1.201 Å)