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8TUR
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Merkel Cell Polyomavirus LTA bipartite NLS bound to importin alpha 2
Descriptor: Importin subunit alpha-1, Truncated large T antigen
Authors:Cross, E.M, Forwood, J.K, Alvisi, G.
Deposit date:2023-08-17
Release date:2024-02-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals.
Protein Sci., 33, 2024
1Q1T
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BU of 1q1t by Molmil
Mouse Importin alpha: non-phosphorylated SV40 CN peptide complex
Descriptor: Importin alpha-2 subunit, Large T antigen
Authors:Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B.
Deposit date:2003-07-22
Release date:2004-03-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha
Biochem.J., 375, 2003
1Q1S
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BU of 1q1s by Molmil
Mouse Importin alpha- phosphorylated SV40 CN peptide complex
Descriptor: Importin alpha-2 subunit, Large T antigen
Authors:Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B.
Deposit date:2003-07-22
Release date:2004-03-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha
Biochem.J., 375, 2003
5XZX
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BU of 5xzx by Molmil
Crystal structure of importin-alpha3 bound to the nuclear localization signal of Ran-binding protein 3
Descriptor: Importin subunit alpha-3, Ran-binding protein 3
Authors:Koyama, M, Matsuura, Y.
Deposit date:2017-07-14
Release date:2017-08-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of importin-alpha 3 bound to the nuclear localization signal of Ran-binding protein 3
Biochem. Biophys. Res. Commun., 491, 2017
3FEY
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BU of 3fey by Molmil
Crystal structure of the CBC-importin alpha complex.
Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2
Authors:Dias, S.M.G, Ambrosio, A.L.B, Cerione, R.A.
Deposit date:2008-12-01
Release date:2009-08-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The molecular basis for the regulation of the cap-binding complex by the importins.
Nat.Struct.Mol.Biol., 16, 2009
3FEX
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BU of 3fex by Molmil
Crystal structure of the CBC-importin alpha complex.
Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2
Authors:Dias, S.M.G, Ambrosio, A.L.B, Cerione, R.A.
Deposit date:2008-12-01
Release date:2009-08-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.549 Å)
Cite:The molecular basis for the regulation of the cap-binding complex by the importins.
Nat.Struct.Mol.Biol., 16, 2009
5K9S
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BU of 5k9s by Molmil
Importin-alpha in complex with HNF1-beta peptide
Descriptor: HNF1 beta A splice variant 2, Importin subunit alpha-1
Authors:Wiedmann, M.M, Aibara, S, Spring, D.R, Stewart, M, Brenton, J.
Deposit date:2016-06-01
Release date:2016-11-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Importin-alpha in complex with HNF1-beta peptide
To Be Published
6BWB
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BU of 6bwb by Molmil
Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 3
Descriptor: Importin subunit alpha-3, Protein W
Authors:Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-14
Release date:2018-07-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BWA
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BU of 6bwa by Molmil
Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 2
Descriptor: Importin subunit alpha-3, Protein W
Authors:Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-14
Release date:2018-07-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BW9
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BU of 6bw9 by Molmil
Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 1
Descriptor: Importin subunit alpha-3, Protein W
Authors:Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-14
Release date:2018-07-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BW1
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BU of 6bw1 by Molmil
Hendra virus W protein C-terminus in complex with Importin alpha 1
Descriptor: Importin subunit alpha-1, Protein W
Authors:Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-14
Release date:2018-07-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
7N9H
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BU of 7n9h by Molmil
Structure of the mammalian importin a1 bound to the TDP-43 NLS
Descriptor: Importin subunit alpha-1, TAR DNA-binding protein 43
Authors:Doll, S.G, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-06-17
Release date:2022-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Recognition of the TDP-43 nuclear localization signal by importin alpha 1/ beta.
Cell Rep, 39, 2022
6BW0
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BU of 6bw0 by Molmil
Nipah virus W protein C-terminus in complex with Importin alpha 1
Descriptor: Importin subunit alpha-1, Protein W
Authors:Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-14
Release date:2018-07-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
5B56
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BU of 5b56 by Molmil
Crystal structure of HIV-1 VPR C-Terminal domain and DIBB-M-Importin-Alpha2 complex
Descriptor: Importin subunit alpha-1, Protein Vpr
Authors:Miyatake, H, Sanjoh, A, Matusda, G, Murakami, T, Murakami, H, Hagiwara, K, Yokoyama, M, Sato, H, Miyamoto, Y, Dohmae, N, Aida, Y.
Deposit date:2016-04-25
Release date:2016-06-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular Mechanism of HIV-1 Vpr for Binding to Importin-alpha
J.Mol.Biol., 428, 2016
6BVV
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BU of 6bvv by Molmil
Nipah virus W protein C-terminus in complex with Importin alpha 3
Descriptor: Importin subunit alpha-3, Protein W
Authors:Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-13
Release date:2018-07-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
5TBK
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BU of 5tbk by Molmil
Crystal structure of human importin a3 bound to RCC1
Descriptor: Importin subunit alpha-3, Regulator of chromosome condensation
Authors:Sankhala, R.S, Lokareddy, R.K, Pumroy, R.A, Cingolani, G.
Deposit date:2016-09-12
Release date:2017-09-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1.
Nat Commun, 8, 2017
3UL1
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BU of 3ul1 by Molmil
Mouse importin alpha: nucleoplasmin cNLS peptide complex
Descriptor: Importin subunit alpha-2, Nucleoplasmin
Authors:Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B.
Deposit date:2011-11-10
Release date:2012-10-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
3UKZ
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BU of 3ukz by Molmil
Mouse importin alpha: mouse CBP80 cNLS complex
Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1
Authors:Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B.
Deposit date:2011-11-10
Release date:2012-10-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
3UL0
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BU of 3ul0 by Molmil
Mouse importin alpha: mouse CBP80Y8D cNLS complex
Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1
Authors:Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B.
Deposit date:2011-11-10
Release date:2012-10-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
3UKY
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BU of 3uky by Molmil
Mouse importin alpha: yeast CBP80 cNLS complex
Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein complex subunit 1
Authors:Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B.
Deposit date:2011-11-10
Release date:2012-10-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
5V5O
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BU of 5v5o by Molmil
Structure of NLS2K of influenza A virus nucleoprotein bound to importin alpha
Descriptor: Importin subunit alpha-1, Nucleoprotein
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2017-03-14
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.243 Å)
Cite:Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin alpha isoforms.
Sci Rep, 7, 2017
5V5P
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BU of 5v5p by Molmil
Structure of NLS2R of influenza A virus nucleoprotein bound to importin alpha
Descriptor: Importin subunit alpha-1, Nucleoprotein
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2017-03-14
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin alpha isoforms.
Sci Rep, 7, 2017
8FK3
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BU of 8fk3 by Molmil
Adeno-Associated Virus Porcine Origin capsid protein basic regions in complex with Importin-alpha 2
Descriptor: Importin subunit alpha-1, VP1
Authors:Hoad, M, Forwood, J.K, Roby, J.A.
Deposit date:2022-12-20
Release date:2023-03-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Characterization of Porcine Adeno-Associated Virus Capsid Protein with Nuclear Trafficking Protein Importin Alpha Reveals a Bipartite Nuclear Localization Signal.
Viruses, 15, 2023
5VQI
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BU of 5vqi by Molmil
Nuclear transport of the Neurospora crassa NIT2 transcription factor is mediated by Importin-alpha
Descriptor: Importin subunit alpha, Nuclear localization sequence of NIT2 transcription factor (NIT2-NLS)
Authors:Bernardes, N.E, Fontes, M.R.M.
Deposit date:2017-05-09
Release date:2017-11-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Nuclear transport of the Neurospora crassa NIT-2 transcription factor is mediated by importin-alpha.
Biochem. J., 474, 2017
3W5K
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BU of 3w5k by Molmil
Crystal structure of Snail1 and importin beta complex
Descriptor: Importin subunit beta-1, ZINC ION, Zinc finger protein SNAI1
Authors:Choi, S, Yamashita, E, Yasuhara, N, Song, J, Son, S.Y, Won, Y.H, Shin, Y.S, Sekimoto, T, Park, I.Y, Yoneda, Y, Lee, S.J.
Deposit date:2013-01-30
Release date:2014-03-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the selective nuclear import of the C2H2 zinc-finger protein Snail by importin beta.
Acta Crystallogr.,Sect.D, 70, 2014

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PDB entries from 2024-08-14

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