4RQE
 
 | | human Seryl-tRNA synthetase dimer complexed with two molecules of tRNAsec | | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SERINE, Serine--tRNA ligase, ... | | Authors: | Xie, W, Wang, C, Guo, Y, Tian, Q, Jia, Q. | | Deposit date: | 2014-11-03 | | Release date: | 2015-11-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | SerRS-tRNASec complex structures reveal mechanism of the first step in selenocysteine biosynthesis.
Nucleic Acids Res., 43, 2015
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2CV0
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2CV2
 | | Glutamyl-tRNA synthetase from Thermus thermophilus in complex with tRNA(Glu) and an enzyme inhibitor, Glu-AMS | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, O5'-(L-GLUTAMYL-SULFAMOYL)-ADENOSINE, ... | | Authors: | Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-05-31 | | Release date: | 2006-09-05 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Structural bases of transfer RNA-dependent amino acid recognition and activation by glutamyl-tRNA synthetase
Structure, 14, 2006
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1BBU
 | | LYSYL-TRNA SYNTHETASE (LYSS) COMPLEXED WITH LYSINE | | Descriptor: | LYSINE, PROTEIN (LYSYL-TRNA SYNTHETASE) | | Authors: | Onesti, S, Desogus, G, Brevet, A, Chen, J, Plateau, P, Blanquet, S, Brick, P. | | Deposit date: | 1998-04-24 | | Release date: | 2000-11-10 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural studies of lysyl-tRNA synthetase: conformational changes induced by substrate binding.
Biochemistry, 39, 2000
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1BBW
 | | LYSYL-TRNA SYNTHETASE (LYSS) | | Descriptor: | PROTEIN (LYSYL-TRNA SYNTHETASE) | | Authors: | Onesti, S, Desogus, G, Brevet, A, Chen, J, Plateau, P, Blanquet, S, Brick, P. | | Deposit date: | 1998-04-24 | | Release date: | 2000-11-10 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural studies of lysyl-tRNA synthetase: conformational changes induced by substrate binding.
Biochemistry, 39, 2000
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2CUZ
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6Y4B
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5UJI
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5XIX
 | | The canonical domain of human asparaginyl-tRNA synthetase | | Descriptor: | Asparagine--tRNA ligase, cytoplasmic, GLYCEROL | | Authors: | Park, J.S, Han, B.W. | | Deposit date: | 2017-04-28 | | Release date: | 2018-05-02 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Unique N-terminal extension domain of human asparaginyl-tRNA synthetase elicits CCR3-mediated chemokine activity.
Int. J. Biol. Macromol., 120, 2018
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1F7U
 | | CRYSTAL STRUCTURE OF THE ARGINYL-TRNA SYNTHETASE COMPLEXED WITH THE TRNA(ARG) AND L-ARG | | Descriptor: | ARGININE, ARGINYL-TRNA SYNTHETASE, SULFATE ION, ... | | Authors: | Delagoutte, B, Moras, D, Cavarelli, J. | | Deposit date: | 2000-06-28 | | Release date: | 2001-06-27 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | tRNA aminoacylation by arginyl-tRNA synthetase: induced conformations during substrates binding
EMBO J., 19, 2000
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5K0S
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5K0T
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3VJR
 | | Crystal structure of Peptidyl-tRNA hydrolase from Escherichia coli in complex with the CCA-acceptor-T[PSI]C domain of tRNA | | Descriptor: | Peptidyl-tRNA hydrolase, tRNA CCA-acceptor | | Authors: | Ito, K, Murakami, R, Mochizuki, M, Qi, H, Shimizu, Y, Miura, K.I, Ueda, T, Uchiumi, T. | | Deposit date: | 2011-10-28 | | Release date: | 2012-09-12 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis for the substrate recognition and catalysis of peptidyl-tRNA hydrolase.
Nucleic Acids Res., 40, 2012
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2KQR
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3ND3
 | | Uhelix 16-mer dsRNA | | Descriptor: | 5'-R(*AP*GP*AP*GP*AP*AP*GP*AP*UP*UP*UP*UP*UP*UP*UP*U)-3', POTASSIUM ION, SODIUM ION | | Authors: | Mooers, B.H, Singh, A. | | Deposit date: | 2010-06-07 | | Release date: | 2011-09-21 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.37 Å) | | Cite: | The crystal structure of an oligo(U):pre-mRNA duplex from a trypanosome RNA editing substrate.
Rna, 17, 2011
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3ND4
 | | Watson-Crick 16-mer dsRNA | | Descriptor: | 5'-R(*AP*GP*AP*GP*AP*AP*GP*AP*UP*CP*UP*UP*CP*UP*CP*U)-3', MAGNESIUM ION, POTASSIUM ION, ... | | Authors: | Mooers, B.H, Singh, A. | | Deposit date: | 2010-06-07 | | Release date: | 2011-09-21 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.524 Å) | | Cite: | The crystal structure of an oligo(U):pre-mRNA duplex from a trypanosome RNA editing substrate.
Rna, 17, 2011
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3EGN
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7WRS
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7WAL
 | | Glutamyl-tRNA synthetase from Plasmodium falciparum (PfERS) in complex with Co | | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, COBALT (II) ION, ... | | Authors: | Sharma, V, Manickam, Y, Babbar, P, Sharma, A. | | Deposit date: | 2021-12-14 | | Release date: | 2022-12-21 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Structural characterization of glutamyl-tRNA synthetase (GluRS) from Plasmodium falciparum.
Mol.Biochem.Parasitol., 253, 2022
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7WAK
 | | Glutamyl-tRNA synthetase from Plasmodium falciparum (PfERS) in complex with ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Glutamyl-tRNA synthetase, ... | | Authors: | Sharma, V, Manickam, Y, Babbar, P, Sharma, A. | | Deposit date: | 2021-12-14 | | Release date: | 2022-12-21 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.782 Å) | | Cite: | Structural characterization of glutamyl-tRNA synthetase (GluRS) from Plasmodium falciparum.
Mol.Biochem.Parasitol., 253, 2022
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7WAJ
 | | Glutamyl-tRNA synthetase from Plasmodium falciparum (PfERS) complexed with ATP and Co | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | | Authors: | Sharma, V, Manickam, Y, Babbar, P, Sharma, A. | | Deposit date: | 2021-12-14 | | Release date: | 2022-12-21 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.254 Å) | | Cite: | Structural characterization of glutamyl-tRNA synthetase (GluRS) from Plasmodium falciparum.
Mol.Biochem.Parasitol., 253, 2022
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7WAI
 | | Glutamyl-tRNA synthetase from Plasmodium falciparum (PfERS) | | Descriptor: | CHLORIDE ION, Glutamyl-tRNA synthetase | | Authors: | Sharma, V, Manickam, Y, Harlos, K, Sharma, A. | | Deposit date: | 2021-12-14 | | Release date: | 2022-12-21 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.105 Å) | | Cite: | Structural characterization of glutamyl-tRNA synthetase (GluRS) from Plasmodium falciparum.
Mol.Biochem.Parasitol., 253, 2022
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7WAO
 | | Glutamyl-tRNA synthetase from Plasmodium falciparum (PfERS) in complex with Mn | | Descriptor: | CHLORIDE ION, Glutamyl-tRNA synthetase, MANGANESE (II) ION | | Authors: | Sharma, V, Manickam, Y, Babbar, P, Sharma, A. | | Deposit date: | 2021-12-14 | | Release date: | 2022-12-21 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.582 Å) | | Cite: | Structural characterization of glutamyl-tRNA synthetase (GluRS) from Plasmodium falciparum.
Mol.Biochem.Parasitol., 253, 2022
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7VC1
 | | Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor L95 and L-proline in space group P21 | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | | Authors: | Yogavel, M, Malhotra, N, Sharma, A. | | Deposit date: | 2021-09-01 | | Release date: | 2022-09-07 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.892 Å) | | Cite: | Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis.
Plos Pathog., 19, 2023
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7VC3
 | | Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor L97 and L-proline at 1.97 A resolution | | Descriptor: | 4-[(3S)-3-cyclopropyl-3-(hydroxymethyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide, CHLORIDE ION, ETHANOLAMINE, ... | | Authors: | Malhotra, N, Yogavel, M, Sharma, A. | | Deposit date: | 2021-09-01 | | Release date: | 2022-09-07 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.973 Å) | | Cite: | Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis.
Plos Pathog., 19, 2023
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