4AQ7

Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucyl-adenylate analogue in the aminoacylation conformation

Summary for 4AQ7

Related2AJG 2AJH 2AJI 4ARC 4ARI 4AS1
DescriptorLEUCINE--TRNA LIGASE, E. COLI TRNALEU UAA ISOACCEPTOR, ZINC ION, ... (7 entities in total)
Functional Keywordsligase-rna complex, ligase, nucleotide(atp)-binding, protein biosynthesis, class i aminoacyl-trna synthetase, atp-binding, metal-binding, ligase/rna
Biological sourceESCHERICHIA COLI
Cellular locationCytoplasm P07813
Total number of polymer chains4
Total molecular weight256271.75
Authors
Palencia, A.,Crepin, T.,Vu, M.T.,Lincecum Jr, T.L.,Martinis, S.A.,Cusack, S. (deposition date: 2012-04-13, release date: 2012-06-13, Last modification date: 2012-10-31)
Primary citation
Palencia, A.,Crepin, T.,Vu, M.T.,Lincecum Jr, T.L.,Martinis, S.A.,Cusack, S.
Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase
Nat.Struct.Mol.Biol., 19:677-, 2012
PubMed: 22683997 (PDB entries with the same primary citation)
DOI: 10.1038/NSMB.2317
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.25080.9%7.7%3.6%0.44MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report