4AQ7

Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucyl-adenylate analogue in the aminoacylation conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, D)	LEUCINE--TRNA LIGASE	polymer	880	99516.0	2	UniProt (P07813) Pfam (PF09334) Pfam (PF13603) Pfam (PF00133) Pfam (PF08264)	ESCHERICHIA COLI	LEUCYL-TRNA SYNTHETASE, LEURS
2	B, D (B, E)	E. COLI TRNALEU UAA ISOACCEPTOR	polymer	87	28052.7	2		ESCHERICHIA COLI
3	E, I (A, D)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	F, J (A, D)	[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDRO-2-FURANYL]METHYL SULFAMATE	non-polymer		346.3	2	Chemie (LMS)
5	G, K (A, D)	LEUCINE	non-polymer		131.2	2	Chemie (LEU)
6	H, L (B, E)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
7	M, N, O, P (A, B, D, E)	water	water		18.0	169	Chemie (HOH)

Sequence modifications

A, D: 1 - 860 (UniProt: P07813)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	255137.3
Non-Polymers*	Number of molecules	8
	Total formula weight	1134.4
All*	Total formula weight	256271.8

*Water molecules are not included.