5H7L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h7l by Molmil](/molmil-images/mine/5h7l) | Complex of Elongation factor 2-50S ribosomal protein L12 | Descriptor: | 50S ribosomal protein L12, Elongation factor 2, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | Authors: | Tanzawa, T, Kato, K, Uchiumi, T, Yao, M. | Deposit date: | 2016-11-18 | Release date: | 2018-02-21 | Last modified: | 2018-05-02 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The C-terminal helix of ribosomal P stalk recognizes a hydrophobic groove of elongation factor 2 in a novel fashion Nucleic Acids Res., 46, 2018
|
|
5H7J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h7j by Molmil](/molmil-images/mine/5h7j) | Crystal structure of Elongation factor 2 | Descriptor: | Elongation factor 2, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | Authors: | Tanzawa, T, Kato, K, Uchiumi, T, Yao, M. | Deposit date: | 2016-11-18 | Release date: | 2018-02-21 | Last modified: | 2018-05-02 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The C-terminal helix of ribosomal P stalk recognizes a hydrophobic groove of elongation factor 2 in a novel fashion Nucleic Acids Res., 46, 2018
|
|
4C0S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4c0s by Molmil](/molmil-images/mine/4c0s) | Mammalian translation elongation factor eEF1A2 | Descriptor: | ELONGATION FACTOR 1-ALPHA 2, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Crepin, T, Shalak, V.F, Yaremchuk, A.D, Vlasenko, D.O, McCarthy, A.A, Negrutskii, B.S, Tukalo, M.A, El'skaya, A.V. | Deposit date: | 2013-08-07 | Release date: | 2014-08-27 | Last modified: | 2017-01-25 | Method: | X-RAY DIFFRACTION (2.703 Å) | Cite: | Mammalian Translation Elongation Factor Eef1A2: X-Ray Structure and New Features of Gdp/GTP Exchange Mechanism in Higher Eukaryotes Nucleic Acids Res., 42, 2014
|
|
7PAO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pao by Molmil](/molmil-images/mine/7pao) | 70S ribosome with EF-G, A*- and P/E-site tRNAs in Mycoplasma pneumoniae cells | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Xue, L, Lenz, S, Rappsilber, J, Mahamid, J. | Deposit date: | 2021-07-30 | Release date: | 2022-05-25 | Last modified: | 2022-10-19 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Visualizing translation dynamics at atomic detail inside a bacterial cell. Nature, 610, 2022
|
|
7PAJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7paj by Molmil](/molmil-images/mine/7paj) | 70S ribosome with EF-Tu-tRNA, P- and E-site tRNAs in Mycoplasma pneumoniae cells | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Xue, L, Lenz, S, Rappsilber, J, Mahamid, J. | Deposit date: | 2021-07-30 | Release date: | 2022-05-25 | Last modified: | 2022-10-19 | Method: | ELECTRON MICROSCOPY (7.3 Å) | Cite: | Visualizing translation dynamics at atomic detail inside a bacterial cell. Nature, 610, 2022
|
|
5A9Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5a9y by Molmil](/molmil-images/mine/5a9y) | Structure of ppGpp BipA | Descriptor: | GTP-BINDING PROTEIN, GUANOSINE-5',3'-TETRAPHOSPHATE | Authors: | Kumar, V, Chen, Y, Ero, R, Li, Z, Gao, Y.-G. | Deposit date: | 2015-07-23 | Release date: | 2015-08-26 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
4G5G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4g5g by Molmil](/molmil-images/mine/4g5g) | ef-tu (Escherichia coli) complexed with nvp-ldu796 | Descriptor: | Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Palestrant, D. | Deposit date: | 2012-07-17 | Release date: | 2012-12-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Antibiotic optimization and chemical structure stabilization of thiomuracin A. J.Med.Chem., 55, 2012
|
|
7OYA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7oya by Molmil](/molmil-images/mine/7oya) | Cryo-EM structure of the 1 hpf zebrafish embryo 80S ribosome | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | Authors: | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | Deposit date: | 2021-06-24 | Release date: | 2022-07-13 | Last modified: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature, 613, 2023
|
|
7OYC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7oyc by Molmil](/molmil-images/mine/7oyc) | Cryo-EM structure of the Xenopus egg 80S ribosome | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | Deposit date: | 2021-06-24 | Release date: | 2022-07-20 | Last modified: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature, 613, 2023
|
|
6XK9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xk9 by Molmil](/molmil-images/mine/6xk9) | Cereblon in complex with DDB1, CC-90009, and GSPT1 | Descriptor: | 2-(4-chlorophenyl)-N-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)-2,2-difluoroacetamide, DNA damage-binding protein 1, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, ... | Authors: | Clayton, T.L, Tran, E.T, Zhu, J, Pagarigan, B.E, Matyskiela, M.E, Chamberlain, P.P. | Deposit date: | 2020-06-25 | Release date: | 2020-12-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.64 Å) | Cite: | CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells. Blood, 137, 2021
|
|
7PJY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pjy by Molmil](/molmil-images/mine/7pjy) | Structure of the 70S-EF-G-GDP ribosome complex with tRNAs in chimeric state 1 (CHI1-EF-G-GDP) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Petrychenko, V, Peng, B.Z, Schwarzer, A.C, Peske, F, Rodnina, M.V, Fischer, N. | Deposit date: | 2021-08-24 | Release date: | 2021-10-20 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural mechanism of GTPase-powered ribosome-tRNA movement. Nat Commun, 12, 2021
|
|
7PJV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pjv by Molmil](/molmil-images/mine/7pjv) | Structure of the 70S-EF-G-GDP-Pi ribosome complex with tRNAs in hybrid state 1 (H1-EF-G-GDP-Pi) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Petrychenko, V, Peng, B.Z, Schwarzer, A.C, Peske, F, Rodnina, M.V, Fischer, N. | Deposit date: | 2021-08-24 | Release date: | 2021-10-20 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural mechanism of GTPase-powered ribosome-tRNA movement. Nat Commun, 12, 2021
|
|
7VOK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vok by Molmil](/molmil-images/mine/7vok) | |
6YBV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ybv by Molmil](/molmil-images/mine/6ybv) | Structure of a human 48S translational initiation complex - eIF2-TC | Descriptor: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ... | Authors: | Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V. | Deposit date: | 2020-03-17 | Release date: | 2020-09-16 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of a human 48Stranslational initiation complex. Science, 369, 2020
|
|
6YDP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ydp by Molmil](/molmil-images/mine/6ydp) | |
6YDW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ydw by Molmil](/molmil-images/mine/6ydw) | |
7W5B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w5b by Molmil](/molmil-images/mine/7w5b) | The cryo-EM structure of human C* complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-06-22 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
|
|
7W5A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w5a by Molmil](/molmil-images/mine/7w5a) | The cryo-EM structure of human pre-C*-II complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-06-22 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
|
|
7W59
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w59 by Molmil](/molmil-images/mine/7w59) | The cryo-EM structure of human pre-C*-I complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-06-22 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
|
|
4FN5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4fn5 by Molmil](/molmil-images/mine/4fn5) | |
5A9V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5a9v by Molmil](/molmil-images/mine/5a9v) | Structure of apo BipA | Descriptor: | GTP-BINDING PROTEIN | Authors: | Kumar, V, Chen, Y, Ero, R, Li, Z, Gao, Y. | Deposit date: | 2015-07-23 | Release date: | 2015-09-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
1OB5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ob5 by Molmil](/molmil-images/mine/1ob5) | T. aquaticus elongation factor EF-Tu complexed with the antibiotic enacyloxin IIa, a GTP analog, and Phe-tRNA | Descriptor: | ELONGATION FACTOR TU, ENACYLOXIN IIA, MAGNESIUM ION, ... | Authors: | Dahlberg, C, Nielsen, R.C, Parmeggiani, A, Nyborg, J, Nissen, P. | Deposit date: | 2003-01-24 | Release date: | 2005-10-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Enacyloxin Iia Pinpoints a Binding Pocket of Elongation Factor TU for Development of Novel Antibiotics. J.Biol.Chem., 281, 2006
|
|
5AFI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5afi by Molmil](/molmil-images/mine/5afi) | 2.9A Structure of E. coli ribosome-EF-TU complex by cs-corrected cryo-EM | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Fischer, N, Neumann, P, Konevega, A.L, Bock, L.V, Ficner, R, Rodnina, M.V, Stark, H. | Deposit date: | 2015-01-22 | Release date: | 2015-03-11 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure of the E. coli ribosome-EF-Tu complex at <3 angstrom resolution by Cs-corrected cryo-EM. Nature, 520, 2015
|
|
5A9Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5a9z by Molmil](/molmil-images/mine/5a9z) | Complex of Thermous thermophilus ribosome bound to BipA-GDPCP | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Kumar, V, Chen, Y, Ahmed, T, Tan, J, Ero, R, Bhushan, S, Gao, Y.-G. | Deposit date: | 2015-07-23 | Release date: | 2015-10-14 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
1N0V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1n0v by Molmil](/molmil-images/mine/1n0v) | Crystal structure of elongation factor 2 | Descriptor: | Elongation factor 2 | Authors: | Joergensen, R, Ortiz, P.A, Carr-Schmid, A, Nissen, P, Kinzy, T.G, Andersen, G.R. | Deposit date: | 2002-10-15 | Release date: | 2002-11-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase. Nat.Struct.Biol., 10, 2003
|
|