8I0D
| Sb3GT1 375S/Q377H mutant complex with UDP-Glc | Descriptor: | Glycosyltransferase, URIDINE-5'-DIPHOSPHATE-GLUCOSE | Authors: | Wang, H.T, Wang, Z.L, Ye, M. | Deposit date: | 2023-01-10 | Release date: | 2023-09-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Insights into the missing apiosylation step in flavonoid apiosides biosynthesis of Leguminosae plants. Nat Commun, 14, 2023
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8I3C
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2RP1
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2REA
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8I38
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2RDV
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2RGK
| Functional annotation of Escherichia coli yihS-encoded protein | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Uncharacterized sugar isomerase yihS | Authors: | Itoh, T, Mikami, B, Hashimoto, W, Murata, K. | Deposit date: | 2007-10-03 | Release date: | 2008-08-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of YihS in complex with D-mannose: structural annotation of Escherichia coli and Salmonella enterica yihS-encoded proteins to an aldose-ketose isomerase J.Mol.Biol., 377, 2008
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8I3A
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2RJ3
| Crystal Structure of the Uridine Phosphorylase from Salmonella Typhimurium in Complex with Uracil and Phosphate Ion at 2.49A Resolution | Descriptor: | PHOSPHATE ION, URACIL, Uridine phosphorylase | Authors: | Timofeev, V.I, Pavlyuk, B.P, Lashkov, A.A, Gabdoulkhakov, A.G, Mikhailov, A.M. | Deposit date: | 2007-10-14 | Release date: | 2008-10-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Crystal Structure of the Uridine Phosphorylase from Salmonella Typhimurium in Complex with Uracil and Phosphate Ion at 2.49A Resolution To be published
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8HXX
| Cryo-EM structure of the histone deacetylase complex Rpd3S | Descriptor: | Chromatin modification-related protein EAF3, Histone H3, Histone deacetylase RPD3, ... | Authors: | Cui, H, Wang, H. | Deposit date: | 2023-01-05 | Release date: | 2023-09-27 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of histone deacetylase complex Rpd3S bound to nucleosome. Nat.Struct.Mol.Biol., 30, 2023
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8IA9
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8IAA
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4PE8
| Crystal structure of TatD in complex with trinucleotide DNA | Descriptor: | DNA (5'-D(*GP*CP*T)-3'), Tat-linked quality control protein TatD | Authors: | Chen, Y, Li, C.-L, Hsiao, Y.-Y, Duh, Y, Yuan, H.S. | Deposit date: | 2014-04-23 | Release date: | 2014-08-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.894 Å) | Cite: | Structure and function of TatD exonuclease in DNA repair. Nucleic Acids Res., 42, 2014
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2TMK
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8ILS
| Cryo-EM structure of PI3Kalpha in complex with compound 17 | Descriptor: | N-[(2R)-1-(ethylamino)-1-oxidanylidene-3-[4-(2-quinoxalin-6-ylethynyl)phenyl]propan-2-yl]-2,3-dimethyl-quinoxaline-6-carboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Authors: | Zhou, Q, Liu, X, Neri, D, Li, W, Favalli, N, Bassi, G, Yang, S, Yang, D, Vogt, P.K, Wang, M.-W. | Deposit date: | 2023-03-04 | Release date: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into the interaction of three Y-shaped ligands with PI3K alpha. Proc.Natl.Acad.Sci.USA, 120, 2023
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4PFB
| Crystal structure of a TRAP periplasmic solute binding protein from Fusobacterium nucleatun (FN1258, TARGET EFI-510120) with bound SN-glycerol-3-phosphate | Descriptor: | C4-dicarboxylate-binding protein, IMIDAZOLE, SN-GLYCEROL-3-PHOSPHATE, ... | Authors: | Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Stead, M, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2014-04-28 | Release date: | 2014-05-14 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry, 54, 2015
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8HX6
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5I78
| Crystal structure of a beta-1,4-endoglucanase from Aspergillus niger | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Endo-beta-1, ... | Authors: | Liu, W.D, Yan, J.J, Li, Y.J, Zheng, Y.Y, Chen, C.C, Guo, R.T. | Deposit date: | 2016-02-17 | Release date: | 2016-12-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Functional and structural analysis of Pichia pastoris-expressed Aspergillus niger 1,4-beta-endoglucanase Biochem. Biophys. Res. Commun., 475, 2016
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8IDB
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8IM3
| Crystal structure of human HPPD complexed with compound a10 | Descriptor: | 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION, [1,3-diethyl-2,2-bis(oxidanylidene)-2$l^{6},1,3-benzothiadiazol-5-yl]-(1-methyl-5-oxidanyl-pyrazol-4-yl)methanone | Authors: | Dong, J, Lin, H.-Y. | Deposit date: | 2023-03-05 | Release date: | 2023-10-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Structure-based discovery of pyrazole-benzothiadiazole hybrid as human HPPD inhibitors. Structure, 31, 2023
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4PGD
| MHC Class I in complex with modified Sendai virus nucleoprotein peptide FAPGNYPAF | Descriptor: | Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ... | Authors: | Celie, P, Joosten, R.P, Perrakis, A, Neefjes, J. | Deposit date: | 2014-05-01 | Release date: | 2015-01-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The first step of peptide selection in antigen presentation by MHC class I molecules. Proc.Natl.Acad.Sci.USA, 112, 2015
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2RQJ
| Quadruplex structure of an RNA aptamer against bovine prion protein | Descriptor: | RNA (5'-R(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3') | Authors: | Katahira, M, Mashima, T, Matsugami, A, Nishikawa, F, Nishikawa, S. | Deposit date: | 2009-07-18 | Release date: | 2009-11-17 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Unique quadruplex structure and interaction of an RNA aptamer against bovine prion protein Nucleic Acids Res., 37, 2009
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8IBQ
| Bromodomain and Extra-terminal Domain (BET) BRD4 | Descriptor: | 7-[2-fluoranyl-3-(1,3,5-trimethylpyrazol-4-yl)phenyl]-1~{H}-imidazo[4,5-b]pyridine, Bromodomain-containing protein 4 | Authors: | Cao, D, Zhiyan, D, Xiong, B. | Deposit date: | 2023-02-10 | Release date: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Discovery of 1 H -Imidazo[4,5- b ]pyridine Derivatives as Potent and Selective BET Inhibitors for the Management of Neuropathic Pain. J.Med.Chem., 66, 2023
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8HX7
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8HX9
| Crystal structure of 4-amino-4-deoxychorismate synthase from Streptomyces venezuelae with chorismate | Descriptor: | (3R,4R)-3-[(1-carboxyethenyl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic acid, 4-amino-4-deoxychorismate synthase, FORMIC ACID, ... | Authors: | Nakamichi, Y, Watanabe, M. | Deposit date: | 2023-01-04 | Release date: | 2023-10-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Structural basis for the allosteric pathway of 4-amino-4-deoxychorismate synthase. Acta Crystallogr D Struct Biol, 79, 2023
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