3MUR
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![BU of 3mur by Molmil](/molmil-images/mine/3mur) | Crystal Structure of the C92U mutant c-di-GMP riboswith bound to c-di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), C92U mutant c-di-GMP riboswitch, MAGNESIUM ION, ... | Authors: | Strobel, S.A, Smith, K.D. | Deposit date: | 2010-05-03 | Release date: | 2010-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch . Biochemistry, 49, 2010
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3E55
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![BU of 3e55 by Molmil](/molmil-images/mine/3e55) | Carbonmonoxy Sperm Whale Myoglobin at 100 K: Laser off | Descriptor: | CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Tomita, A, Sato, T, Ichiyanagi, K, Nozawa, S, Ichikawa, H, Chollet, M, Kawai, F, Park, S.-Y, Koshihara, S, Adachi, S. | Deposit date: | 2008-08-13 | Release date: | 2009-02-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | Visualizing breathing motion of internal cavities in concert with ligand migration in myoglobin Proc.Natl.Acad.Sci.USA, 106, 2009
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1O7S
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![BU of 1o7s by Molmil](/molmil-images/mine/1o7s) | High resolution structure of Siglec-7 | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, ... | Authors: | Alphey, M.S, Attrill, H, Crocker, P.R, Van Aalten, D.M.F. | Deposit date: | 2002-11-12 | Release date: | 2003-03-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | High Resolution Structures of Siglec-7 - Insights Into Ligand Specificity in the Siglec Family J.Biol.Chem., 278, 2003
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1O7V
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![BU of 1o7v by Molmil](/molmil-images/mine/1o7v) | High resolution structure of Siglec-7 | Descriptor: | SIALIC ACID BINDING IG-LIKE LECTIN 7, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Alphey, M.S, Attrill, H, Crocker, P.R, Van Aalten, D.M.F. | Deposit date: | 2002-11-14 | Release date: | 2003-03-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | High resolution crystal structures of Siglec-7. Insights into ligand specificity in the Siglec family. J.Biol.Chem., 278, 2003
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4NXH
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![BU of 4nxh by Molmil](/molmil-images/mine/4nxh) | |
3ED9
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![BU of 3ed9 by Molmil](/molmil-images/mine/3ed9) | Carbonmonoxy Sperm Whale Myoglobin at 140 K: Laser on [30 min] | Descriptor: | CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Tomita, A, Sato, T, Ichiyanagi, K, Nozawa, S, Ichikawa, H, Chollet, M, Kawai, F, Park, S.-Y, Koshihara, S, Adachi, S. | Deposit date: | 2008-09-02 | Release date: | 2009-02-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | Visualizing breathing motion of internal cavities in concert with ligand migration in myoglobin. Proc.Natl.Acad.Sci.USA, 106, 2009
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1V66
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![BU of 1v66 by Molmil](/molmil-images/mine/1v66) | Solution structure of human p53 binding domain of PIAS-1 | Descriptor: | Protein inhibitor of activated STAT protein 1 | Authors: | Okubo, S, Hara, F, Tsuchida, Y, Shimotakahara, S, Suzuki, S, Hatanaka, H, Yokoyama, S, Tanaka, H, Yasuda, H, Shindo, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-11-27 | Release date: | 2004-12-07 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | NMR structure of the N-terminal domain of SUMO ligase PIAS1 and its interaction with tumor suppressor p53 and A/T-rich DNA oligomers J.Biol.Chem., 279, 2004
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2AR5
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![BU of 2ar5 by Molmil](/molmil-images/mine/2ar5) | |
2ISJ
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![BU of 2isj by Molmil](/molmil-images/mine/2isj) | BluB bound to oxidized FMN | Descriptor: | BluB, FLAVIN MONONUCLEOTIDE | Authors: | Larsen, N.A, Taga, M.E, Howard-Jones, A.R, Walsh, C.T, Walker, G.C. | Deposit date: | 2006-10-17 | Release date: | 2007-03-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | BluB cannibalizes flavin to form the lower ligand of vitamin B12. Nature, 446, 2007
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4ADZ
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![BU of 4adz by Molmil](/molmil-images/mine/4adz) | |
3MXH
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![BU of 3mxh by Molmil](/molmil-images/mine/3mxh) | Native structure of a c-di-GMP riboswitch from V. cholerae | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, U1 small nuclear ribonucleoprotein A, ... | Authors: | Strobel, S.A, Smith, K.D. | Deposit date: | 2010-05-07 | Release date: | 2010-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch . Biochemistry, 49, 2010
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1Z9J
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![BU of 1z9j by Molmil](/molmil-images/mine/1z9j) | Photosynthetic Reaction Center from Rhodobacter sphaeroides | Descriptor: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (III) ION, ... | Authors: | Thielges, M, Uyeda, G, Camara-Artigas, A, Kalman, L, Williams, J.C, Allen, J.P. | Deposit date: | 2005-04-02 | Release date: | 2005-06-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Design of a Redox-Linked Active Metal Site: Manganese Bound to Bacterial Reaction Centers at a Site Resembling That of Photosystem II Biochemistry, 44, 2005
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4FDK
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![BU of 4fdk by Molmil](/molmil-images/mine/4fdk) | F78L Tt H-NOX | Descriptor: | Methyl-accepting chemotaxis protein, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Weinert, E.E, Phillips-Piro, C.M, Marletta, M.A. | Deposit date: | 2012-05-28 | Release date: | 2013-08-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Porphyrin pi-stacking in a heme protein scaffold tunes gas ligand affinity. J.Inorg.Biochem., 127C, 2013
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8VYC
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3GA5
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![BU of 3ga5 by Molmil](/molmil-images/mine/3ga5) | X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with (2R)-glyceryl-beta-D-galactopyranoside | Descriptor: | (2R)-2,3-dihydroxypropyl beta-D-galactopyranoside, CALCIUM ION, D-galactose-binding periplasmic protein, ... | Authors: | Sooriyaarachchi, S, Ubhayasekera, W, Mowbray, S.L. | Deposit date: | 2009-02-16 | Release date: | 2009-04-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with the physiological ligand, (2R)-glyceryl-beta-D-galactopyranoside Febs J., 276, 2009
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1DB1
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![BU of 1db1 by Molmil](/molmil-images/mine/1db1) | CRYSTAL STRUCTURE OF THE NUCLEAR RECEPTOR FOR VITAMIN D COMPLEXED TO VITAMIN D | Descriptor: | 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, VITAMIN D NUCLEAR RECEPTOR | Authors: | Rochel, N, Wurtz, J.M, Mitschler, A, Klaholz, B, Moras, D. | Deposit date: | 1999-11-02 | Release date: | 2000-01-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand. Mol.Cell, 5, 2000
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7U2K
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![BU of 7u2k by Molmil](/molmil-images/mine/7u2k) | C6-guano bound Mu Opioid Receptor-Gi Protein Complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Wang, H, Kobilka, B. | Deposit date: | 2022-02-24 | Release date: | 2022-12-07 | Last modified: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure-based design of bitopic ligands for the μ-opioid receptor. Nature, 613, 2023
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4GXY
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![BU of 4gxy by Molmil](/molmil-images/mine/4gxy) | RNA structure | Descriptor: | Adenosylcobalamin, Adenosylcobalamin riboswitch, IRIDIUM HEXAMMINE ION, ... | Authors: | Serganov, A, Peselis, A. | Deposit date: | 2012-09-04 | Release date: | 2012-10-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural insights into ligand binding and gene expression control by an adenosylcobalamin riboswitch. Nat.Struct.Mol.Biol., 19, 2012
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4JYX
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![BU of 4jyx by Molmil](/molmil-images/mine/4jyx) | Crystal structure of polyprenyl synthase PATL_3739 (TARGET EFI-509195) FROM PSEUDOALTEROMONAS ATLANTICA, COMPLEX WITH INORGANIC PHOSPHATE AND AN UNKNOWN LIGAND | Descriptor: | PHOSPHATE ION, Trans-hexaprenyltranstransferase, UNKNOWN LIGAND | Authors: | Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Al Obaidi, N, Stead, M, Love, J, Poulter, C.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2013-04-01 | Release date: | 2013-04-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of Isoprenoid Synthase Patl_3739 from Pseudoalteromonas Atlantica To be Published
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3RYM
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![BU of 3rym by Molmil](/molmil-images/mine/3rym) | Structure of Oxidized M98K mutant of Amicyanin | Descriptor: | Amicyanin, ZINC ION | Authors: | Sukumar, N, Davidson, V.L. | Deposit date: | 2011-05-11 | Release date: | 2011-11-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7039 Å) | Cite: | Replacement of the axial copper ligand methionine with lysine in amicyanin converts it to a zinc-binding protein that no longer binds copper. J.Inorg.Biochem., 105, 2011
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5OPY
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![BU of 5opy by Molmil](/molmil-images/mine/5opy) | Crystal structure of anti-alphaVbeta3 integrin Fab LM609 | Descriptor: | Heavy chain of LM609 Fab (antigen-binding fragment), Light chain of LM609 Fab (antigen-binding fragment) | Authors: | Backovic, M, Veesler, D, Borst, A.J, James, Z.M, Zagotta, W, Ginsberg, M, Rey, F.A, DiMaio, F. | Deposit date: | 2017-08-10 | Release date: | 2017-10-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance. Structure, 25, 2017
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2ISL
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![BU of 2isl by Molmil](/molmil-images/mine/2isl) | BluB bound to reduced flavin (FMNH2) and molecular oxygen. (clear crystal form) | Descriptor: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, BluB, OXYGEN MOLECULE | Authors: | Larsen, N.A, Taga, M.E, Howard-Jones, A.R, Walsh, C.T, Walker, G.C. | Deposit date: | 2006-10-17 | Release date: | 2007-03-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | BluB cannibalizes flavin to form the lower ligand of vitamin B12. Nature, 446, 2007
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3KQR
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![BU of 3kqr by Molmil](/molmil-images/mine/3kqr) | The structure of serum amyloid p component bound to phosphoethanolamine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER, ... | Authors: | Mikolajek, H, Kolstoe, S.E, Wood, S.P, Pepys, M.B. | Deposit date: | 2009-11-17 | Release date: | 2010-12-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis of ligand specificity in the human pentraxins, C-reactive protein and serum amyloid P component. J.Mol.Recognit., 24, 2011
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1N6V
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![BU of 1n6v by Molmil](/molmil-images/mine/1n6v) | Average structure of the interferon-binding ectodomain of the human type I interferon receptor | Descriptor: | Interferon-alpha/beta receptor beta chain | Authors: | Chill, J.H, Quadt, S.R, Levy, R, Schreiber, G, Anglister, J. | Deposit date: | 2002-11-12 | Release date: | 2003-07-15 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | The human type I interferon receptor. NMR structure reveals the molecular basis of ligand binding. Structure, 11, 2003
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3MUM
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![BU of 3mum by Molmil](/molmil-images/mine/3mum) | Crystal Structure of the G20A mutant c-di-GMP riboswith bound to c-di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), G20A mutant c-di-GMP Riboswitch, MAGNESIUM ION, ... | Authors: | Strobel, S.A, Smith, K.D. | Deposit date: | 2010-05-03 | Release date: | 2010-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch . Biochemistry, 49, 2010
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