3S9N
 
 | | Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, room temperature | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CARBONATE ION, ... | | Authors: | Eckenroth, B.E, Steere, A.N, Mason, A.B, Everse, S.J. | | Deposit date: | 2011-06-01 | | Release date: | 2011-08-10 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH.
Proc.Natl.Acad.Sci.USA, 108, 2011
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2KC2
 | | NMR structure of the F1 domain (residues 86-202) of the talin | | Descriptor: | Talin-1 | | Authors: | Goult, B.T, Elliott, P.R, Roberts, G.C.K, Critchely, D.R, Barsukov, I.L. | | Deposit date: | 2008-12-13 | | Release date: | 2010-01-19 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
Embo J., 29, 2010
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2KGB
 | | NMR solution of the regulatory domain cardiac F77W-Troponin C in complex with the cardiac Troponin I 144-163 switch peptide | | Descriptor: | CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ... | | Authors: | Mercier, P, Julien, O, Crane, M.L, Sykes, B.D. | | Deposit date: | 2009-03-07 | | Release date: | 2009-03-24 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The effect of the cosolvent trifluoroethanol on a tryptophan side chain orientation in the hydrophobic core of troponin C.
Protein Sci., 18, 2009
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2IXR
 | | BipD of Burkholderia Pseudomallei | | Descriptor: | MEMBRANE ANTIGEN | | Authors: | Roversi, P, Johnson, S, Field, T, Deane, J.E, Galyov, E.E, Lea, S.M. | | Deposit date: | 2006-07-10 | | Release date: | 2006-11-02 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Self-Chaperoning of the Type III Secretion System Needle Tip Proteins Ipad and Bipd.
J.Biol.Chem., 282, 2007
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8D4F
 | | beta-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-01 | | Release date: | 2023-06-14 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (9.8 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D4E
 | | Asymmetric unit of AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-01 | | Release date: | 2023-06-14 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (9.2 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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2H8H
 | | Src kinase in complex with a quinazoline inhibitor | | Descriptor: | N-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-7-[2-(4-METHYLPIPERAZIN-1-YL)ETHOXY]-5-(TETRAHYDRO-2H-PYRAN-4-YLOXY)QUINAZOLIN-4-AMINE, Proto-oncogene tyrosine-protein kinase Src | | Authors: | Otterbein, L.R, Norman, R, Pauptit, R.A, Rowsell, S, Breed, J. | | Deposit date: | 2006-06-07 | | Release date: | 2006-11-21 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor.
J.Med.Chem., 49, 2006
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3SHG
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8D4G
 | | gamma-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-01 | | Release date: | 2023-06-14 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (11.6 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D4D
 | | gamma-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated narrow membrane tubes | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-01 | | Release date: | 2023-06-14 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (9.6 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D4C
 | | beta-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated narrow membrane tubes | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-01 | | Release date: | 2023-06-14 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (9.3 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D9W
 | | beta-Arf1 homodimeric interface within AP-1, Arf1, Nef, MHC-I lattice on narrow tubes | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.H, Hurley, J.H. | | Deposit date: | 2022-06-11 | | Release date: | 2023-07-05 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (9.3 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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3SWK
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8DVR
 | | Cryo-EM structure of RIG-I bound to the end of p3SLR30 (+AMPPNP) | | Descriptor: | Antiviral innate immune response receptor RIG-I, GUANOSINE-5'-TRIPHOSPHATE, ZINC ION, ... | | Authors: | Wang, W, Pyle, A.M. | | Deposit date: | 2022-07-29 | | Release date: | 2022-11-02 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
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2K4P
 | | Solution Structure of Ship2-Sam | | Descriptor: | Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 | | Authors: | Leone, M, Pellecchia, M. | | Deposit date: | 2008-06-16 | | Release date: | 2008-11-25 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | NMR Studies of a Heterotypic Sam-Sam Domain Association: The Interaction between the Lipid Phosphatase Ship2 and the EphA2 Receptor.
Biochemistry, 47, 2008
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8DVS
 | | Cryo-EM structure of RIG-I bound to the end of OHSLR30 (+ATP) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Antiviral innate immune response receptor RIG-I, MAGNESIUM ION, ... | | Authors: | Wang, W, Pyle, A.M. | | Deposit date: | 2022-07-29 | | Release date: | 2022-11-16 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
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8DVU
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2KC1
 | | NMR structure of the F0 domain (residues 0-85) of the talin ferm domain | | Descriptor: | MKIAA1027 protein | | Authors: | Goult, B.T, Elliott, P.R, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L. | | Deposit date: | 2008-12-13 | | Release date: | 2010-01-19 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
Embo J., 29, 2010
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3Q0K
 | | Crystal structure of Human PACSIN 2 F-BAR | | Descriptor: | CALCIUM ION, Protein kinase C and casein kinase substrate in neurons protein 2 | | Authors: | Bai, X, Meng, G, Zheng, X. | | Deposit date: | 2010-12-15 | | Release date: | 2012-02-15 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of human PACSIN 2 F-BAR domain
To be Published
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2KSO
 | | EphA2:SHIP2 SAM:SAM complex | | Descriptor: | Ephrin type-A receptor 2, Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 | | Authors: | Hota, P.K, Preeti, C, Stetzik, L, Kim, S, Wang, B, Lee, H, Buck, M. | | Deposit date: | 2010-01-10 | | Release date: | 2011-07-27 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structure and function of the EphA2:SHIP2 SAM domain heterodimer
To be Published
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8ARD
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2FN5
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2CDT
 | | alpha-SPECTRIN SH3 DOMAIN A56S MUTANT | | Descriptor: | SPECTRIN ALPHA CHAIN | | Authors: | Casares, S, Camara-Artigas, A, Vega, M.C, Lopez-Mayorga, O, Conejero-Lara, F. | | Deposit date: | 2006-01-27 | | Release date: | 2007-02-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.54 Å) | | Cite: | Cooperative Propagation of Local Stability Changes from Low-Stability and High-Stability Regions in a SH3 Domain.
Proteins: Struct., Funct., Bioinf., 67, 2007
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3R1X
 | | Crystal structure of 2-oxo-3-deoxygalactonate kinase from Klebsiella pneumoniae | | Descriptor: | 2-oxo-3-deoxygalactonate kinase, FORMIC ACID, GLYCEROL | | Authors: | Michalska, K, Cuff, M.E, Tesar, C, Feldmann, B, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2011-03-11 | | Release date: | 2011-04-13 | | Last modified: | 2011-09-21 | | Method: | X-RAY DIFFRACTION (2.093 Å) | | Cite: | Structure of 2-oxo-3-deoxygalactonate kinase from Klebsiella pneumoniae.
Acta Crystallogr.,Sect.D, 67, 2011
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2KRD
 | | Solution Structure of the Regulatory Domain of Human Cardiac Troponin C in Complex with the Switch Region of cardiac Troponin I and W7 | | Descriptor: | CALCIUM ION, N-(6-AMINOHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE, Troponin C, ... | | Authors: | Oleszczuk, M, Robertson, I.M, Li, M.X, Sykes, B.D. | | Deposit date: | 2009-12-16 | | Release date: | 2010-02-16 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the regulatory domain of human cardiac troponin C in complex with the switch region of cardiac troponin I and W7: the basis of W7 as an inhibitor of cardiac muscle contraction.
J.MOL.CELL.CARDIOL., 48, 2010
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