7OIM
 
 | | Mouse RNF213, with mixed nucleotides bound | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, E3 ubiquitin-protein ligase RNF213, ... | | Authors: | Grabarczyk, D, Ahel, J, Clausen, T. | | Deposit date: | 2021-05-11 | | Release date: | 2022-06-01 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | E3 ubiquitin ligase RNF213 employs a non-canonical zinc finger active site and is allosterically regulated by ATP
To Be Published
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8HST
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8PBD
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6XNZ
 | | Structure of RAG1 (R848M/E649V)-RAG2-DNA Target Capture Complex | | Descriptor: | 12RSS integration strand (34-mer), 12RSS non-integration strand (34-mer), 23RSS integration strand (45-mer), ... | | Authors: | Zhang, Y, Corbett, E, Wu, S, Schatz, D.G. | | Deposit date: | 2020-07-05 | | Release date: | 2020-08-26 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase.
Embo J., 39, 2020
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6CIL
 | | PRE-REACTION COMPLEX, RAG1(E962Q)/2-INTACT/INTACT 12/23RSS COMPLEX IN MN2+ | | Descriptor: | High mobility group protein B1, Intact 12RSS substrate forward strand, Intact 12RSS substrate reverse strand, ... | | Authors: | Chuenchor, W, Chen, X, Kim, M.S, Gellert, M, Yang, W. | | Deposit date: | 2018-02-24 | | Release date: | 2018-04-25 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (4.15 Å) | | Cite: | Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
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5M8C
 | | Spliceosome component | | Descriptor: | Pre-mRNA-processing factor 19 | | Authors: | Moura, T.R, Pena, V. | | Deposit date: | 2016-10-28 | | Release date: | 2018-02-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors.
Mol. Cell, 69, 2018
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2YB6
 | | Native human Rad6 | | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, UBIQUITIN-CONJUGATING ENZYME E2 B | | Authors: | Hibbert, R.G, Sixma, T.K. | | Deposit date: | 2011-03-02 | | Release date: | 2011-04-20 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | E3 Ligase Rad18 Promotes Monoubiquitination Rather Than Ubiquitin Chain Formation by E2 Enzyme Rad6.
Proc.Natl.Acad.Sci.USA, 108, 2011
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5M89
 | | Spliceosome component | | Descriptor: | Spliceosome WD40 Sc | | Authors: | Moura, T.R, Pena, V. | | Deposit date: | 2016-10-28 | | Release date: | 2018-03-14 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.605 Å) | | Cite: | Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors.
Mol. Cell, 69, 2018
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6GVW
 | | Crystal structure of the BRCA1-A complex | | Descriptor: | BRCA1-A complex subunit Abraxas 1, BRCA1-A complex subunit RAP80, BRISC and BRCA1-A complex member 1, ... | | Authors: | Bunker, R.D, Rabl, J, Thoma, N.H. | | Deposit date: | 2018-06-21 | | Release date: | 2019-07-10 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (3.75 Å) | | Cite: | Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation.
Mol.Cell, 75, 2019
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6H3C
 | | Cryo-EM structure of the BRISC complex bound to SHMT2 | | Descriptor: | BRISC and BRCA1-A complex member 1, BRISC and BRCA1-A complex member 2, BRISC complex subunit Abraxas 2, ... | | Authors: | Bunker, R.D, Rabl, J, Thoma, N.H. | | Deposit date: | 2018-07-18 | | Release date: | 2019-07-10 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation.
Mol.Cell, 75, 2019
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7BGB
 | | The H/ACA RNP lobe of human telomerase | | Descriptor: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | | Authors: | Nguyen, T.H.D, Ghanim, G.E, Fountain, A.J, van Roon, A.M.M, Rangan, R, Das, R, Collins, K. | | Deposit date: | 2021-01-06 | | Release date: | 2021-04-28 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of human telomerase holoenzyme with bound telomeric DNA.
Nature, 593, 2021
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5M88
 | | Spliceosome component | | Descriptor: | Core | | Authors: | Moura, T.R, Pena, V. | | Deposit date: | 2016-10-28 | | Release date: | 2018-02-28 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors.
Mol. Cell, 69, 2018
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2QM4
 | | Crystal structure of human XLF/Cernunnos, a non-homologous end-joining factor | | Descriptor: | Non-homologous end-joining factor 1 | | Authors: | Li, Y, Chirgadze, D.Y, Sibanda, B.L, Bolanos-Garcia, V.M, Davies, O.R, Blundell, T.L. | | Deposit date: | 2007-07-14 | | Release date: | 2007-12-11 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ.
Embo J., 27, 2008
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5WY5
 | | Crystal structure of MAGEG1 and NSE1 complex | | Descriptor: | MAGNESIUM ION, Melanoma-associated antigen G1, Non-structural maintenance of chromosomes element 1 homolog, ... | | Authors: | Yang, M, Gao, J. | | Deposit date: | 2017-01-11 | | Release date: | 2017-05-03 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.92 Å) | | Cite: | Mage-Ring Protein Complexes Comprise A Family Of E3 Ubiquitin Ligases.
Mol.Cell, 39, 2010
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4ZYN
 | | Crystal Structure of Parkin E3 ubiquitin ligase (linker deletion; delta 86-130) | | Descriptor: | E3 ubiquitin-protein ligase parkin, SULFATE ION, ZINC ION | | Authors: | Lilov, A, Sauve, V, Trempe, J.F, Rodionov, D, Wang, J, Gehring, K. | | Deposit date: | 2015-05-21 | | Release date: | 2015-08-19 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.54 Å) | | Cite: | A Ubl/ubiquitin switch in the activation of Parkin.
Embo J., 34, 2015
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3P87
 | | Structure of human PCNA bound to RNASEH2B PIP box peptide | | Descriptor: | Proliferating cell nuclear antigen, Ribonuclease H2 subunit B | | Authors: | Bubeck, D, Reijns, M.A, Graham, S.C, Astell, K.R, Jones, E.Y, Jackson, A.P. | | Deposit date: | 2010-10-13 | | Release date: | 2011-02-02 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.99 Å) | | Cite: | PCNA directs type 2 RNase H activity on DNA replication and repair substrates.
Nucleic Acids Res., 39, 2011
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4Y18
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4Y2G
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5KGF
 | | Structural model of 53BP1 bound to a ubiquitylated and methylated nucleosome, at 4.5 A resolution | | Descriptor: | DNA (145-MER), Histone H2A type 1, Histone H2B type 1-C/E/F/G/I, ... | | Authors: | Wilson, M.D, Benlekbir, S, Sicheri, F, Rubinstein, J.L, Durocher, D. | | Deposit date: | 2016-06-13 | | Release date: | 2016-07-27 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (4.54 Å) | | Cite: | The structural basis of modified nucleosome recognition by 53BP1.
Nature, 536, 2016
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2Z6K
 | | Crystal structure of full-length human RPA14/32 heterodimer | | Descriptor: | Replication protein A 14 kDa subunit, Replication protein A 32 kDa subunit | | Authors: | Deng, X, Habel, J.E, Kabaleeswaran, V, Borgstahl, G.E. | | Deposit date: | 2007-08-03 | | Release date: | 2007-12-04 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of the Full-length Human RPA14/32 Complex Gives Insights into the Mechanism of DNA Binding and Complex Formation
J.Mol.Biol., 374, 2007
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7LIO
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7LIQ
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7LIP
 | | X-ray structure of SPOP MATH domain (D140G) | | Descriptor: | SULFATE ION, Speckle-type POZ protein | | Authors: | Botuyan, M.V, Cui, G, Mer, G. | | Deposit date: | 2021-01-27 | | Release date: | 2021-04-14 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication.
Sci Adv, 7, 2021
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7LIN
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6BRP
 | | F-box protein form 2 | | Descriptor: | F-box/LRR-repeat MAX2 homolog, SKP1-like protein 1A | | Authors: | Shabek, N, Zheng, N, Mao, H, Hinds, T.R, Ticchiarelli, F, Leyser, O. | | Deposit date: | 2017-11-30 | | Release date: | 2018-11-21 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Structural plasticity of D3-D14 ubiquitin ligase in strigolactone signalling.
Nature, 563, 2018
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