4ZYE
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![BU of 4zye by Molmil](/molmil-images/mine/4zye) | |
7EEO
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7EEN
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1NLW
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![BU of 1nlw by Molmil](/molmil-images/mine/1nlw) | Crystal structure of Mad-Max recognizing DNA | Descriptor: | 5'-D(*GP*AP*GP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*CP*TP*C)-3', MAD PROTEIN, MAX PROTEIN | Authors: | Nair, S.K, Burley, S.K. | Deposit date: | 2003-01-07 | Release date: | 2003-02-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structures of Myc-Max and Mad-Max recognizing DNA: Molecular bases of regulation by proto-oncogenic transcription factors Cell(Cambridge,Mass.), 112, 2003
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7T7H
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![BU of 7t7h by Molmil](/molmil-images/mine/7t7h) | Crystal structure of Vaccinia Virus decapping enzyme D9 in complex with inhibitor CP100356 | Descriptor: | 4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxyquinazolin-2-amine, DNA repair NTP-phosphohydrolase, SODIUM ION | Authors: | Peters, J.K, Gross, J.D. | Deposit date: | 2021-12-15 | Release date: | 2022-06-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.78000259 Å) | Cite: | Fluorescence-Based Activity Screening Assay Reveals Small Molecule Inhibitors of Vaccinia Virus mRNA Decapping Enzyme D9. Acs Chem.Biol., 17, 2022
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2GN5
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6JTZ
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![BU of 6jtz by Molmil](/molmil-images/mine/6jtz) | Crystal Structure of hRecQ1_D2-Zn-WH containing mutation on beta-hairpin | Descriptor: | ATP-dependent DNA helicase Q1, ZINC ION | Authors: | Das, T, Mukhopadhyay, S, Bose, M, Das, A.K, Ganguly, A. | Deposit date: | 2019-04-12 | Release date: | 2020-04-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.797 Å) | Cite: | Residues at the interface between zinc binding and winged helix domains of human RECQ1 play a significant role in DNA strand annealing activity. Nucleic Acids Res., 2021
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7CFA
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8W1P
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6EO2
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7KFU
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![BU of 7kfu by Molmil](/molmil-images/mine/7kfu) | Cas6-RT-Cas1--Cas2 complex | Descriptor: | Cas2, Cas6-RT-Cas1 | Authors: | Hoel, C.M, Wang, J.Y, Doudna, J.A, Brohawn, S.G. | Deposit date: | 2020-10-14 | Release date: | 2021-03-31 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex. Nat Commun, 12, 2021
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7KFT
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![BU of 7kft by Molmil](/molmil-images/mine/7kft) | Partial Cas6-RT-Cas1--Cas2 complex | Descriptor: | Cas2, Cas6-RT-Cas1 | Authors: | Hoel, C.M, Wang, J.Y, Doudna, J.A, Brohawn, S.G. | Deposit date: | 2020-10-14 | Release date: | 2021-03-31 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex. Nat Commun, 12, 2021
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2CZR
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![BU of 2czr by Molmil](/molmil-images/mine/2czr) | Crystal structure of TBP-interacting protein (Tk-TIP26) and implications for its inhibition mechanism of the interaction between TBP and TATA-DNA | Descriptor: | GLYCEROL, TBP-interacting protein, ZINC ION | Authors: | Yamamoto, T, Matsuda, T, Inoue, T, Matsumura, H, Morikawa, M, Kanaya, S, Kai, Y. | Deposit date: | 2005-07-15 | Release date: | 2006-02-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of TBP-interacting protein (Tk-TIP26) and implications for its inhibition mechanism of the interaction between TBP and TATA-DNA Protein Sci., 15, 2006
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4OGE
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![BU of 4oge by Molmil](/molmil-images/mine/4oge) | Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii | Descriptor: | HNH endonuclease domain protein, MAGNESIUM ION, SPERMIDINE, ... | Authors: | Jiang, F, Ma, E, Lin, S, Doudna, J.A. | Deposit date: | 2014-01-15 | Release date: | 2014-02-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.201 Å) | Cite: | Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science, 343, 2014
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2R2S
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![BU of 2r2s by Molmil](/molmil-images/mine/2r2s) | Co(III)bleomycinB2 bound to d(ATTAGTTATAACTAAT) complexed with MMLV RT catalytic fragment | Descriptor: | BLEOMYCIN B2, COBALT (III) ION, DNA (5'-D(*DAP*DTP*DTP*DAP*DGP*DTP*DT)-3'), ... | Authors: | Goodwin, K.D, Lewis, M.A, Long, E.C, Georgiadis, M.M. | Deposit date: | 2007-08-27 | Release date: | 2008-07-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding. Proc.Natl.Acad.Sci.Usa, 105, 2008
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2KWQ
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![BU of 2kwq by Molmil](/molmil-images/mine/2kwq) | Mcm10 C-terminal DNA binding domain | Descriptor: | Protein MCM10 homolog, ZINC ION | Authors: | Robertson, P.D, Chagot, B, Chazin, W.J, Eichman, B.F. | Deposit date: | 2010-04-15 | Release date: | 2010-05-19 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of the C-terminal DNA binding domain of Mcm10 reveals a conserved MCM motif. J.Biol.Chem., 285, 2010
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2FJ7
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![BU of 2fj7 by Molmil](/molmil-images/mine/2fj7) | Crystal structure of Nucleosome Core Particle Containing a Poly (dA.dT) Sequence Element | Descriptor: | 147 bp DNA containing 16 bp poly dA element, 147 bp DNA containing 16 bp poly dT element, Histone H2B, ... | Authors: | Bao, Y, White, C.L, Luger, K. | Deposit date: | 2005-12-31 | Release date: | 2006-09-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Nucleosome Core Particles Containing a Poly(dA.dT) Sequence Element Exhibit a Locally Distorted DNA Structure. J.Mol.Biol., 361, 2006
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2IHN
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![BU of 2ihn by Molmil](/molmil-images/mine/2ihn) | Co-crystal of Bacteriophage T4 RNase H with a fork DNA substrate | Descriptor: | 5'-D(*CP*TP*AP*AP*CP*TP*TP*TP*GP*AP*GP*GP*CP*AP*GP*AP*CP*C)-3', 5'-D(*GP*GP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*TP*AP*GP*TP*CP*AP*A)-3', Ribonuclease H | Authors: | Devos, J.M, Mueser, T.C. | Deposit date: | 2006-09-26 | Release date: | 2007-08-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of bacteriophage T4 5' nuclease in complex with a branched DNA reveals how FEN-1 family nucleases bind their substrates. J.Biol.Chem., 282, 2007
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1R9W
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8RCF
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![BU of 8rcf by Molmil](/molmil-images/mine/8rcf) | RAD51 nucleoprotein filament on double-stranded abasic DNA | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*CP*AP*CP*CP*AP*CP*CP*AP*CP*CP*AP*CP*CP*AP*CP*CP*AP*CP*CP*AP*CP*CP*A)-3'), ... | Authors: | Appleby, R, Pellegrini, L. | Deposit date: | 2023-12-06 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | CryoEM structure of the RAD51 nucleoprotein filament on double-stranded abasic DNA To Be Published
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1UE5
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![BU of 1ue5 by Molmil](/molmil-images/mine/1ue5) | Crystal structure of the single-stranded dna-binding protein from mycobacterium tuberculosis | Descriptor: | CADMIUM ION, Single-strand binding protein | Authors: | Saikrishnan, K, Jeyakanthan, J, Venkatesh, J, Acharya, N, Sekar, K, Varshney, U, Vijayan, M, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2003-05-09 | Release date: | 2004-02-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of Mycobacterium tuberculosis single-stranded DNA-binding protein. Variability in quaternary structure and its implications J.MOL.BIOL., 331, 2003
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2J09
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![BU of 2j09 by Molmil](/molmil-images/mine/2j09) | Thermus DNA photolyase with FMN antenna chromophore | Descriptor: | CHLORIDE ION, DEOXYRIBODIPYRIMIDINE PHOTO-LYASE, FLAVIN MONONUCLEOTIDE, ... | Authors: | Klar, T, Kaiser, G, Hennecke, U, Carell, T, Batschauer, A, Essen, L.-O. | Deposit date: | 2006-08-01 | Release date: | 2007-05-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Natural and Non-Natural Antenna Chromophores in the DNA Photolyase from Thermus Thermophilus Chembiochem, 7, 2006
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4DDQ
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2I9K
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![BU of 2i9k by Molmil](/molmil-images/mine/2i9k) | Engineered Extrahelical Base Destabilization Enhances Sequence Discrimination of DNA Methyltransferase M.HhaI | Descriptor: | 5'-D(*T*GP*AP*TP*AP*GP*CP*GP*CP*TP*AP*TP*C)-3', Modification methylase HhaI, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Youngblood, B, Shieh, F.K, De Los Rios, S, Perona, J.J, Reich, N.O. | Deposit date: | 2006-09-05 | Release date: | 2006-10-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Engineered Extrahelical Base Destabilization Enhances Sequence Discrimination of DNA Methyltransferase M.HhaI J.Mol.Biol., 362, 2006
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173D
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![BU of 173d by Molmil](/molmil-images/mine/173d) | MULTIPLE BINDING MODES OF ANTICANCER DRUG ACTINOMYCIN D: X-RAY, MOLECULAR MODELING, AND SPECTROSCOPIC STUDIES OF D(GAAGCTTC)2-ACTINOMYCIN D COMPLEXES AND ITS HOST DNA | Descriptor: | ACTINOMYCIN D, DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3') | Authors: | Kamitori, S, Takusagawa, F. | Deposit date: | 1994-04-18 | Release date: | 1994-10-15 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Multiple Binding Modes of Anticancer Drug Actinomycin D: X-Ray, Molecular Modeling, and Spectroscopic Studies of D(Gaagcttc)2-Actinomycin D Complexes and its Host DNA J.Am.Chem.Soc., 116, 1994
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