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2UUG	ESCHERICHIA COLI URACIL-DNA GLYCOSYLASE:INHIBITOR COMPLEX WITH H187D MUTANT UDG AND WILD-TYPE UGI 分子名称: URACIL-DNA GLYCOSYLASE, URACIL-DNA GLYCOSYLASE INHIBITOR 著者 Putnam, C.D, Arvai, A.S, Mol, C.D, Tainer, J.A. 登録日 1998-10-31 公開日 1999-03-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Protein mimicry of DNA from crystal structures of the uracil-DNA glycosylase inhibitor protein and its complex with Escherichia coli uracil-DNA glycosylase J.Mol.Biol., 287, 1999
2ZHX	Crystal structure of Uracil-DNA Glycosylase from Mycobacterium tuberculosis in complex with a proteinaceous inhibitor 分子名称: Uracil-DNA glycosylase, Uracil-DNA glycosylase inhibitor 著者 Kaushal, P.S, Talawar, R.K, Krishna, P.D.V, Varshney, U, Vijayan, M. 登録日 2008-02-11 公開日 2008-05-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Unique features of the structure and interactions of mycobacterial uracil-DNA glycosylase: structure of a complex of the Mycobacterium tuberculosis enzyme in comparison with those from other sources Acta Crystallogr.,Sect.D, 64, 2008
3A7N	Crystal structure of uracil-DNA glycosylase from Mycobacterium tuberculosis 分子名称: CITRATE ANION, Uracil-DNA glycosylase 著者 Kaushal, P.S, Talawar, R.K, Varshney, U, Vijayan, M. 登録日 2009-09-29 公開日 2010-08-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure of uracil-DNA glycosylase from Mycobacterium tuberculosis: insights into interactions with ligands Acta Crystallogr.,Sect.F, 66, 2010
3CXM	Leishmania naiffi uracil-DNA glycosylase in complex with 5-bromouracil 分子名称: 5-bromopyrimidine-2,4(1H,3H)-dione, BROMIDE ION, GLYCEROL, ... 著者 Larson, E.T, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) 登録日 2008-04-24 公開日 2008-05-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structures of Leishmania naiffi uracil-DNA glycosylase in complex with several ligands identified with fragment cocktail crystallography. To be Published
3EUG	CRYSTAL STRUCTURE OF ESCHERICHIA COLI URACIL DNA GLYCOSYLASE AND ITS COMPLEXES WITH URACIL AND GLYCEROL: STRUCTURE AND GLYCOSYLASE MECHANISM REVISITED 分子名称: GLYCEROL, PROTEIN (GLYCOSYLASE) 著者 Xiao, G, Tordova, M, Jagadeesh, J, Drohat, A.C, Stivers, J.T, Gilliland, G.L. 登録日 1998-10-13 公開日 1999-10-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Crystal structure of Escherichia coli uracil DNA glycosylase and its complexes with uracil and glycerol: structure and glycosylase mechanism revisited. Proteins, 35, 1999
3FCF	Complex of UNG2 and a fragment-based designed inhibitor 分子名称: 3-[(1E,7E)-8-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,6-dioxa-2,7-diazaocta-1,7-dien-1-yl]benzoic acid, THIOCYANATE ION, Uracil-DNA glycosylase 著者 Bianchet, M.A, Chung, S, Parker, J.B, Amzel, L.M, Stivers, J.T. 登録日 2008-11-21 公開日 2009-04-28 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Impact of linker strain and flexibility in the design of a fragment-based inhibitor Nat.Chem.Biol., 5, 2009
3FCI	Complex of UNG2 and a fragment-based designed inhibitor 分子名称: 3-{(E)-[(3-{[(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methyl]amino}propoxy)imino]methyl}benzoic acid, SODIUM ION, THIOCYANATE ION, ... 著者 Bianchet, M.A, Chung, S, Parker, J.B, Amzel, L.M, Stivers, J.T. 登録日 2008-11-21 公開日 2009-04-28 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Impact of linker strain and flexibility in the design of a fragment-based inhibitor Nat.Chem.Biol., 5, 2009
3FCK	Complex of UNG2 and a fragment-based design inhibitor 分子名称: 3-({[3-({[(1E)-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methylidene]amino}oxy)propyl]amino}methyl)benzoic acid, Uracil-DNA glycosylase 著者 Bianchet, M.A, Chung, S, Parker, J.B, Amzel, L.M, Stivers, J.T. 登録日 2008-11-21 公開日 2009-04-28 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Impact of linker strain and flexibility in the design of a fragment-based inhibitor Nat.Chem.Biol., 5, 2009
3FCL	Complex of UNG2 and a fragment-based designed inhibitor 分子名称: 3-{[(4-{[(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methyl]amino}butyl)amino]methyl}benzoic acid, THIOCYANATE ION, Uracil-DNA glycosylase 著者 Bianchet, M.A, Chung, S, Parker, J.B, Amzel, L.M, Stivers, J.T. 登録日 2008-11-21 公開日 2009-04-28 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Impact of linker strain and flexibility in the design of a fragment-based inhibitor Nat.Chem.Biol., 5, 2009
3IKB	The structure of a conserved protein from Streptococcus mutans UA159. 分子名称: CITRATE ANION, uncharacterized conserved protein 著者 Tan, K, Hatzos, C, Buck, K, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2009-08-05 公開日 2009-08-18 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 The structure of a conserved protein from Streptococcus mutans UA159. To be Published
3TKB	crystal structure of human uracil-DNA glycosylase D183G/K302R mutant 分子名称: IMIDAZOLE, Uracil-DNA glycosylase 著者 Assefa, N.G, Niiranen, L, Willassen, N.P, Smalas, A.O, Moe, E. 登録日 2011-08-26 公開日 2011-10-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Thermal unfolding studies of cold adapted uracil-DNA N-glycosylase (UNG) from Atlantic cod (Gadus morhua). A comparative study with human UNG. Comp.Biochem.Physiol. B: Biochem.Mol.Biol., 161, 2012
3TR7	Structure of a uracil-DNA glycosylase (ung) from Coxiella burnetii 分子名称: Uracil-DNA glycosylase 著者 Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. 登録日 2011-09-09 公開日 2011-09-21 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.1958 Å) 主引用文献 Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
3UF7	Co-crystal structure of Escherichia coli uracil-DNA glycosylase and a C-terminal fragement of the single-stranded DNA-binding protein 分子名称: SULFATE ION, Single-stranded DNA-binding protein, Uracil-DNA glycosylase 著者 George, N.P, Liban, T.J, Reyes-Lamothe, R, Keck, J.L. 登録日 2011-10-31 公開日 2012-11-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Identification of the SSB-interaction platform of Escherichia coli uracil-DNA glycosylase To be Published
3UFJ	Human Thymine DNA Glycosylase Bound to Substrate Analog 2'-fluoro-2'-deoxyuridine 分子名称: 5'-D(*CP*AP*GP*CP*TP*CP*TP*GP*TP*AP*CP*GP*TP*GP*AP*GP*CP*AP*GP*TP*GP*GP*A)-3', 5'-D(*CP*CP*AP*CP*TP*GP*CP*TP*CP*AP*(UF2)P*GP*TP*AP*CP*AP*GP*AP*GP*CP*TP*GP*T)-3', G/T mismatch-specific thymine DNA glycosylase 著者 Pozharski, E, Maiti, A, Drohat, A.C. 登録日 2011-11-01 公開日 2012-04-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.967 Å) 主引用文献 Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA. Proc.Natl.Acad.Sci.USA, 109, 2012
3UFM	Co-crystal structure of Deinococcus radiodurans uracil-DNA glycosylase and the C-terminus of the single-stranded DNA-binding protein 分子名称: IODIDE ION, Single-stranded DNA-binding protein, Uracil-DNA glycosylase 著者 George, N.P, Keck, J.L. 登録日 2011-11-01 公開日 2012-11-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Identification of the SSB-interaction platform of Deinococcus radiodurans uracil-DNA glycosylase To be Published
3UO7	Crystal structure of Human Thymine DNA Glycosylase Bound to Substrate 5-carboxylcytosine 分子名称: 5'-D(*CP*AP*GP*CP*TP*CP*TP*GP*TP*AP*CP*AP*TP*GP*AP*GP*CP*AP*GP*TP*GP*GP*A)-3', 5'-D(*CP*CP*AP*CP*TP*GP*CP*TP*CP*AP*(1CC)P*GP*TP*AP*CP*AP*GP*AP*GP*CP*TP*GP*T)-3', G/T mismatch-specific thymine DNA glycosylase 著者 Zhang, L, He, C. 登録日 2011-11-16 公開日 2012-02-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.002 Å) 主引用文献 Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA. Nat.Chem.Biol., 8, 2012
3UOB	Crystal structure of Human Thymine DNA Glycosylase Bound to Substrate Analog 2'-deoxy-2'-beta-fluoro-cytidine 分子名称: 5'-D(*CP*AP*GP*CP*TP*CP*TP*GP*TP*AP*CP*GP*TP*GP*AP*GP*CP*AP*GP*TP*GP*GP*A)-3', 5'-D(*CP*CP*AP*CP*TP*GP*CP*TP*CP*AP*(1FC)P*GP*TP*AP*CP*AP*GP*AP*GP*CP*TP*GP*T)-3', G/T mismatch-specific thymine DNA glycosylase 著者 Zhang, L, He, C. 登録日 2011-11-16 公開日 2012-02-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.011 Å) 主引用文献 Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA. Nat.Chem.Biol., 8, 2012
3WDF	Staphylococcus aureus UDG 分子名称: Uracil-DNA glycosylase 著者 Wang, H.C, Ko, T.P, Wang, A.H.J. 登録日 2013-06-18 公開日 2014-02-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Staphylococcus aureus protein SAUGI acts as a uracil-DNA glycosylase inhibitor. Nucleic Acids Res., 42, 2013
3WDG	Staphylococcus aureus UDG / UGI complex 分子名称: Uncharacterized protein, Uracil-DNA glycosylase 著者 Wang, H.C, Ko, T.P, Wang, A.H.J. 登録日 2013-06-18 公開日 2014-02-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Staphylococcus aureus protein SAUGI acts as a uracil-DNA glycosylase inhibitor. Nucleic Acids Res., 42, 2013
3ZOQ	Structure of BsUDG-p56 complex 分子名称: CHLORIDE ION, GLYCEROL, P56, ... 著者 Banos-Sanz, J.I, Mojardin, L, Sanz-Aparicio, J, Gonzalez, B, Salas, M. 登録日 2013-02-22 公開日 2013-05-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal Structure and Functional Insights Into Uracil-DNA Glycosylase Inhibition by Phage Phi29 DNA Mimic Protein P56 Nucleic Acids Res., 41, 2013
3ZOR	Structure of BsUDG 分子名称: URACIL-DNA GLYCOSYLASE 著者 Banos-Sanz, J.I, Mojardin, L, Sanz-Aparicio, J, Gonzalez, B, Salas, M. 登録日 2013-02-22 公開日 2013-05-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Crystal Structure and Functional Insights Into Uracil-DNA Glycosylase Inhibition by Phage Phi29 DNA Mimic Protein P56 Nucleic Acids Res., 41, 2013
4EUG	Crystallographic and Enzymatic Studies of an Active Site Variant H187Q of Escherichia Coli Uracil DNA Glycosylase: Crystal Structures of Mutant H187Q and its Uracil Complex 分子名称: PROTEIN (GLYCOSYLASE) 著者 Xiao, G, Tordova, M, Drohat, A.C, Jagadeesh, J, Stivers, J.T, Gilliland, G.L. 登録日 1998-12-27 公開日 1999-07-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Heteronuclear NMR and crystallographic studies of wild-type and H187Q Escherichia coli uracil DNA glycosylase: electrophilic catalysis of uracil expulsion by a neutral histidine 187. Biochemistry, 38, 1999
4FNC	Human TDG in a post-reactive complex with 5-hydroxymethyluracil (5hmU) 分子名称: 5-HYDROXYMETHYL URACIL, DNA (28-MER), DNA (29-MER), ... 著者 Hashimoto, H, Hong, S, Bhagwat, A.S, Zhang, X, Cheng, X. 登録日 2012-06-19 公開日 2012-09-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.493 Å) 主引用文献 Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylation. Nucleic Acids Res., 40, 2012
4JGC	Human TDG N140A mutant IN A COMPLEX WITH 5-carboxylcytosine (5caC) 分子名称: 4-amino-2-oxo-1,2-dihydropyrimidine-5-carboxylic acid, G/T mismatch-specific thymine DNA glycosylase, oligonucleotide, ... 著者 Hashimoto, H, Zhang, X, Cheng, X. 登録日 2013-02-28 公開日 2013-05-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.582 Å) 主引用文献 Activity and crystal structure of human thymine DNA glycosylase mutant N140A with 5-carboxylcytosine DNA at low pH. Dna Repair, 12, 2013
4L5N	Crystallographic Structure of HHV-1 Uracil-DNA Glycosylase complexed with the Bacillus phage PZA inhibitor protein p56 分子名称: ACETATE ION, Early protein GP1B, Uracil-DNA glycosylase 著者 Cole, A.R, Sapir, O, Ryzhenkova, K, Baltulionis, G, Hornyak, P, Savva, R. 登録日 2013-06-11 公開日 2013-08-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Architecturally diverse proteins converge on an analogous mechanism to inactivate Uracil-DNA glycosylase. Nucleic Acids Res., 41, 2013

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