3TKB

crystal structure of human uracil-DNA glycosylase D183G/K302R mutant

Summary for 3TKB

Entry DOI	10.2210/pdb3tkb/pdb
Descriptor	Uracil-DNA glycosylase, IMIDAZOLE (3 entities in total)
Functional Keywords	glycosidase, alpha/beta protein, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Isoform 1: Mitochondrion. Isoform 2: Nucleus: P13051
Total number of polymer chains	1
Total formula weight	25652.28
Authors	Assefa, N.G.,Niiranen, L.,Willassen, N.P.,Smalas, A.O.,Moe, E. (deposition date: 2011-08-26, release date: 2011-10-12, Last modification date: 2023-09-13)
Primary citation	Assefa, N.G.,Niiranen, L.,Willassen, N.P.,Smalas, A.,Moe, E. Thermal unfolding studies of cold adapted uracil-DNA N-glycosylase (UNG) from Atlantic cod (Gadus morhua). A comparative study with human UNG. Comp.Biochem.Physiol. B: Biochem.Mol.Biol., 161:60-68, 2012 Cited by PubMed: 21959147 DOI: 10.1016/j.cbpb.2011.09.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation