3TKB
crystal structure of human uracil-DNA glycosylase D183G/K302R mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Uracil-DNA glycosylase | polymer | 223 | 25514.1 | 1 | UniProt (P13051) Pfam (PF03167) | Homo sapiens (human) | UDG |
| 2 | B, C (A) | IMIDAZOLE | non-polymer | 69.1 | 2 | Chemie (IMD) | |||
| 3 | D (A) | water | water | 18.0 | 343 | Chemie (HOH) |
Sequence modifications
A: 85 - 304 (UniProt: P13051)
| PDB | External Database | Details |
|---|---|---|
| Met 82 | - | expression tag |
| Glu 83 | - | expression tag |
| Phe 84 | - | expression tag |
| Gly 183 | Asp 192 | engineered mutation |
| Arg 302 | Lys 311 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25514.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 138.2 | |
| All* | Total formula weight | 25652.3 |
